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Using Brownian Dynamics, we study the dynamical behavior of a polymer grafted onto an adhesive surface close to the mechanically induced adsorption-stretching transition. Even though the transition is first order, (in the infinite chain…

We employ 3D Langevin Dynamics simulations to study the dynamics of polymer chains translocating through a nanopore in presence of asymmetric solvent conditions. Initially a large fraction ($>$ 50%) of the chain is placed at the…

Soft Condensed Matter · Physics 2010-06-09 Christopher Lorscher , Tapio Ala-Nissila , Aniket Bhattacharya

We study dynamics of a Rouse polymer chain, which diffuses in a three-dimensional space under the constraint that one of its ends, referred to as the slip-link, may move only along a one-dimensional line containing randomly placed,…

Statistical Mechanics · Physics 2007-05-23 S. Nechaev , G. Oshanin , A. Blumen

The dynamics of a heteropolymer chain in solution is studied in the limit of long chain length. Using functional integral representation we derive an effective equation of motion, in which the heterogeneity of the chain manifests itself as…

Condensed Matter · Physics 2009-10-28 Jiunn-Ren Roan , E. I. Shakhnovich

We investigate the problem of polymer translocation through a nanopore in the absence of an external driving force. To this end, we use the two-dimensional (2D) fluctuating bond model with single-segment Monte Carlo moves. To overcome the…

Computational Physics · Physics 2012-12-06 Kaifu Luo , Tapio Ala-Nissila , See-chen Ying

In this work we study the noise induced effects on the dynamics of short polymers crossing a potential barrier, in the presence of a metastable state. An improved version of the Rouse model for a flexible polymer has been adopted to mimic…

Statistical Mechanics · Physics 2009-11-13 N. Pizzolato , A. Fiasconaro , B. Spagnolo

Polymer translocation in crowded environments is a ubiquitous phenomenon in biological systems. We studied polymer translocation through a pore in free, one-sided (asymmetric), and two-sided (symmetric) crowded environments. Extensive…

Soft Condensed Matter · Physics 2024-03-01 Vrinda Garg , Rejoy Mathew , Riyan Ibrahim , Kulveer Singh , Surya K. Ghosh

We study the dynamics of an ideal polymer chain in a crowded, viscoelastic medium and in the presence of active forces. The motion of the centre of mass and of individual monomers is calculated. On time scales that are comparable to the…

Soft Condensed Matter · Physics 2015-12-23 Hans Vandebroek , Carlo Vanderzande

We present results from our simulations of biopolymer translocation in a solvent which explain the main experimental findings. The forced translocation can be described by simple force balance arguments for the relevant range of pore…

Biological Physics · Physics 2009-05-08 V. V. Lehtola , R. P. Linna , K. Kaski

In this chapter we review the rich behavior of polymer chains embedded in a quenched random environment. We first consider the problem of a Gaussian chain free to move in a random potential with short-ranged correlations. We derive the…

Disordered Systems and Neural Networks · Physics 2007-05-23 Yadin Y. Goldschmidt , Yohannes Shiferaw

We revise the classical problem of characterizing first exit times of a harmonically trapped particle whose motion is described by one- or multi-dimensional Ornstein-Uhlenbeck process. We start by recalling the main derivation steps of a…

Mathematical Physics · Physics 2025-06-24 D. S. Grebenkov

Motivated by the recent experimental observations of the DNA loop extrusion by protein motors, in this paper we investigate the statistical properties of the growing polymer loops within the ideal chain model. The loop conformation is…

Statistical Mechanics · Physics 2021-04-30 Dmitry Starkov , Vladimir Parfenyev , Sergey Belan

We use Monte Carlo simulations to study polymer melts consisting of fully flexible and moderately stiff chains in the bond fluctuation model at a volume fraction $0.5$. In order to reduce the local density fluctuations, we test a…

Soft Condensed Matter · Physics 2015-06-24 Hsiao-Ping Hsu

The tumbling dynamics of individual polymers in semidilute solution is studied by large-scale non-equilibrium mesoscale hydrodynamic simulations. We find that the tumbling time is equal to the non-equilibrium relaxation time of the polymer…

Soft Condensed Matter · Physics 2011-03-21 C. -C. Huang , G. Sutmann , G. Gompper , R. G. Winkler

The motion involved in barrier crossing for protein folding are investigated in terms of the chain dynamics of the polymer backbone, completing the microscopic description of protein folding presented in the previous paper. Local reaction…

Soft Condensed Matter · Physics 2009-10-31 John J. Portman , Shoji Takada , Peter G. Wolynes

We use an off - lattice bead - spring model of a self - avoiding polymer chain immersed in a 3-dimensional quenched random medium to study chain dynamics by means of a Monte - Carlo (MC) simulation. The chain center of mass mean-squared…

Soft Condensed Matter · Physics 2007-05-23 A. Milchev , V. G. Rostiashvili , T. A. Vilgis

The thermal activation process by which a system passes from one local energy minimum to another is a recurring motif in physics, chemistry, and biology. For instance, biopolymer chains are typically modeled in terms of energy landscapes,…

Statistical Mechanics · Physics 2024-10-01 Sudeep Adhikari , K. S. D. Beach

In this paper, we investigate the use of relaxed logarithmic barrier functions in the context of linear model predictive control. We present results that allow to guarantee asymptotic stability of the corresponding closed-loop system, and…

Optimization and Control · Mathematics 2015-03-12 Christian Feller , Christian Ebenbauer

We present a loop-opening model that accounts for the molecular details of the intrinsic fracture energy for fracturing polymer networks. This model includes not only the energy released from the scission of bridging chains but also the…

Materials Science · Physics 2024-01-31 Shu Wang , Chase M. Hartquist , Bolei Deng , Xuanhe Zhao

We study a one-dimensional run-and-tumble particle (RTP), which is a prototypical model for active system, moving within an arbitrary external potential. Using backward Fokker-Planck equations, we derive the differential equation satisfied…

Statistical Mechanics · Physics 2025-01-27 Mathis Guéneau , Satya N. Majumdar , Gregory Schehr