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Models for dependent data are distinguished by their targets of inference. Marginal models are useful when interest lies in quantifying associations averaged across a population of clusters. When the functional form of a covariate-outcome…

Methodology · Statistics 2022-04-18 Glen McGee , Alex Stringer

The joint analysis of biomedical data in Alzheimer's Disease (AD) is important for better clinical diagnosis and to understand the relationship between biomarkers. However, jointly accounting for heterogeneous measures poses important…

Methodology · Statistics 2018-08-14 Luigi Antelmi , Nicholas Ayache , Philippe Robert , Marco Lorenzi

Normative modelling is an emerging method for understanding the underlying heterogeneity within brain disorders like Alzheimer Disease (AD) by quantifying how each patient deviates from the expected normative pattern that has been learned…

Image and Video Processing · Electrical Eng. & Systems 2026-02-06 Sayantan Kumar , Philip Payne , Aristeidis Sotiras

Federated learning (FL) offers a privacy-centric distributed learning framework, enabling model training on individual clients and central aggregation without necessitating data exchange. Nonetheless, FL implementations often suffer from…

Artificial Intelligence · Computer Science 2024-05-13 Rongyu Zhang , Yun Chen , Chenrui Wu , Fangxin Wang , Bo Li

We propose a model for diagnosing Autism spectrum disorder (ASD) using multimodal magnetic resonance imaging (MRI) data. Our approach integrates brain connectivity data from diffusion tensor imaging (DTI) and functional MRI (fMRI),…

Neurons and Cognition · Quantitative Biology 2024-10-10 Lu Wei , Yi Huang , Guosheng Yin , Fode Zhang , Manxue Zhang , Bin Liu

In neuroimaging data analysis, Gaussian graphical models are often used to model statistical dependencies across spatially remote brain regions known as functional connectivity. Typically, data is collected across a cohort of subjects and…

Machine Learning · Statistics 2015-12-08 Ricardo Pio Monti , Christoforos Anagnostopoulos , Giovanni Montana

The identification of factors associated with mental and behavioral disorders in early childhood is critical both for psychopathology research and the support of primary health care practices. Motivated by the Millennium Cohort Study, in…

Methodology · Statistics 2021-09-15 Luca Merlo , Lea Petrella , Nikos Tzavidis

In this paper, we develop a finite mixture of convolutional distributions, a statistical model to analyze continuous data distributed approximately on a mixture of low-dimensional affine subspaces. The observations are assumed independent…

Statistics Theory · Mathematics 2026-04-21 Sunrit Chakraborty , XuanLong Nguyen

Mixed spatial autoregressive (SAR) models with numerical covariates have been well studied. However, as non-numerical data, such as functional data and compositional data, receive substantial amounts of attention and are applied to…

Applications · Statistics 2018-11-08 Huiwen Wang , Tingting Huang , Shanshan Wang

Covariate adjustment is an approach to improve the precision of trial analyses by adjusting for baseline variables that are prognostic of the primary endpoint. Motivated by the SEARCH Universal HIV Test-and-Treat Trial (2013-2017), we tell…

Methodology · Statistics 2025-12-16 Laura B. Balzer , Mark J. van der Laan , Maya L. Petersen

Federated learning is a distributed paradigm that allows multiple parties to collaboratively train deep models without exchanging the raw data. However, the data distribution among clients is naturally non-i.i.d., which leads to severe…

Machine Learning · Computer Science 2023-01-31 Tianfei Zhou , Ender Konukoglu

Jointly identifying a mixture of discrete and continuous factors of variability without supervision is a key problem in unraveling complex phenomena. Variational inference has emerged as a promising method to learn interpretable mixture…

Machine Learning · Computer Science 2021-04-14 Yeganeh M. Marghi , Rohan Gala , Uygar Sümbül

Autism spectrum disorder (ASD) represents a neurodevelopmental condition characterized by difficulties in expressing emotions and communication, particularly during early childhood. Understanding the affective state of children at an early…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Aura Loredana Dan

Understanding how adult humans learn non-native speech categories such as tone information has shed novel insights into the mechanisms underlying experience-dependent brain plasticity. Scientists have traditionally examined these questions…

Methodology · Statistics 2020-06-16 Giorgio Paulon , Fernando Llanos , Bharath Chandrasekaran , Abhra Sarkar

Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

Neurons and Cognition · Quantitative Biology 2020-03-04 Taban Eslami , Joseph S. Raiker , Fahad Saeed

In this article, we propose a penalized clustering method for large scale data with multiple covariates through a functional data approach. In the proposed method, responses and covariates are linked together through nonparametric…

Methodology · Statistics 2008-01-17 Ping Ma , Wenxuan Zhong

Federated Learning offers a solution for decentralised model training, addressing the difficulties associated with distributed data and privacy in machine learning. However, the fact of data heterogeneity in federated learning frequently…

Machine Learning · Computer Science 2025-09-10 Ozgu Goksu , Nicolas Pugeault

Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…

Neurons and Cognition · Quantitative Biology 2025-12-30 Ashley Chen

Neuroscientific research has revealed that the complex brain network can be organized into distinct functional communities, each characterized by a cohesive group of regions of interest (ROIs) with strong interconnections. These communities…

Neurons and Cognition · Quantitative Biology 2024-03-14 Yanting Yang , Beidi Zhao , Zhuohao Ni , Yize Zhao , Xiaoxiao Li

The joint alignment of multivariate functional data plays an important role in various fields such as signal processing, neuroscience and medicine, including the statistical analysis of data from wearable devices. Traditional methods often…

Signal Processing · Electrical Eng. & Systems 2023-12-18 Vi Thanh Pham , Jonas Bille Nielsen , Klaus Fuglsang Kofoed , Jørgen Tobias Kühl , Andreas Kryger Jensen