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Multi-dimensional functional data arises in numerous modern scientific experimental and observational studies. In this paper we focus on longitudinal functional data, a structured form of multidimensional functional data. Operating within a…

Methodology · Statistics 2019-09-20 John Shamshoian , Damla Senturk , Shafali Jeste , Donatello Telesca

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by complex physiological processes. Previous research has predominantly focused on static cerebral interactions, often neglecting the brain's dynamic nature and…

Machine Learning · Computer Science 2024-09-11 Peng Wang , Xin Wen , Ruochen Cao , Chengxin Gao , Yanrong Hao , Rui Cao

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition marked by disruptions in brain connectivity. Functional MRI (fMRI) offers a non-invasive window into large-scale neural dynamics by measuring…

Machine Learning · Computer Science 2025-08-20 Mohammad Izadi , Mehran Safayani

Researchers continue to be interested in exploring the effects that covariates have on the heterogeneity in trajectories. The inclusion of covariates associated with latent classes allows for a more clear understanding of individual…

Methodology · Statistics 2022-05-10 Jin Liu , Robert A. Perera

Autism Spectrum Disorder (ASD) is a neuro-developmental syndrome resulting from alterations in the embryological brain before birth. This disorder distinguishes its patients by special socially restricted and repetitive behavior in addition…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Hala Shamseddine , Safa Otoum , Azzam Mourad

Objective. The paper investigates the presence of autism using the functional brain connectivity measures derived from electro-encephalogram (EEG) of children during face perception tasks. Approach. Phase synchronized patterns from…

Early identification of Autism Spectrum Disorder (ASD) is considered critical for effective intervention to mitigate emotional, financial and societal burdens. Although ASD belongs to a group of neurodevelopmental disabilities that are not…

Autism Spectrum Disorder (ASD) is a complex neuro-developmental challenge, presenting a spectrum of difficulties in social interaction, communication, and the expression of repetitive behaviors in different situations. This increasing…

Machine Learning · Computer Science 2025-06-16 Mohd Mujtaba Akhtar , Girish , Muskaan Singh , Orchid Chetia Phukan

Autism spectrum disorder (ASD) is a highly disabling mental disease that brings significant impairments of social interaction ability to the patients, making early screening and intervention of ASD critical. With the development of the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Ruimin Ma , Ruitao Xie , Yanlin Wang , Jintao Meng , Yanjie Wei , Wenhui Xi , Yi Pan

Mixed Membership Models (MMMs) are a popular family of latent structure models for complex multivariate data. Instead of forcing each subject to belong to a single cluster, MMMs incorporate a vector of subject-specific weights…

Methodology · Statistics 2023-02-16 Yuqi Gu , Elena A. Erosheva , Gongjun Xu , David B. Dunson

Additive models form a widely popular class of regression models which represent the relation between covariates and response variables as the sum of low-dimensional transfer functions. Besides flexibility and accuracy, a key benefit of…

Machine Learning · Statistics 2015-05-20 Alhussein Fawzi , Mathieu Sinn , Pascal Frossard

Integrating high-dimensional, heterogeneous data from multi-site cohort studies with complex hierarchical structures poses significant feature selection and prediction challenges. We extend the Bayesian Integrative Analysis and Prediction…

Methodology · Statistics 2025-01-30 Aidan Neher , Apostolos Stamenos , Mark Fiecas , Sandra Safo , Thierry Chekouo

This paper develops a novel statistical approach to characterize temporally localised cross-oscillatory interactions between channels in a functional brain network. Brain signals are generally nonstationary and the proposed framework uses…

Methodology · Statistics 2026-02-10 Haibo Wu , Marina I. Knight , Hernando Ombao

The multifactorial etiology of autism spectrum disorder (ASD) suggests that its study would benefit greatly from multimodal approaches that combine data from widely varying platforms, e.g., neuroimaging, genetics, and clinical…

Quantitative Methods · Quantitative Biology 2023-08-11 Nicha C. Dvornek , Catherine Sullivan , James S. Duncan , Abha R. Gupta

The primary goal of this paper is to develop a method that quantifies how activity in one brain region can explain future activity in another region. Here, we propose the mixed effects spectral vector-autoregressive (ME-SpecVar) model to…

Applications · Statistics 2022-10-07 Anastasiia Malinovskaia

In many applications, data can be heterogeneous in the sense of spanning latent groups with different underlying distributions. When predictive models are applied to such data the heterogeneity can affect both predictive performance and…

Machine Learning · Statistics 2022-05-04 Thomas Lartigue , Sach Mukherjee

Over the last years, increasing evidence has fuelled the hypothesis that Autism Spectrum Disorder (ASD) is a condition of altered brain functional connectivity. The great majority of these empirical studies rely on functional magnetic…

Neurons and Cognition · Quantitative Biology 2010-08-02 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Mariano Sigman

Multivariate functional data present theoretical and practical complications which are not found in univariate functional data. One of these is a situation where the component functions of multivariate functional data are positive and are…

Methodology · Statistics 2023-03-09 Cody Carroll , Hans-Georg Müller

The application of machine learning (ML) to electroencephalography (EEG) has great potential to advance both neuroscientific research and clinical applications. However, the generalisability and robustness of EEG-based ML models often hinge…

Signal Processing · Electrical Eng. & Systems 2025-11-03 Philipp Bomatter , Henry Gouk

Depression and Attention Deficit Hyperactivity Disorder (ADHD) stand out as the common mental health challenges today. In affective computing, speech signals serve as effective biomarkers for mental disorder assessment. Current research,…

Audio and Speech Processing · Electrical Eng. & Systems 2025-03-05 Shuanglin Li , Siyang Song , Rajesh Nair , Syed Mohsen Naqvi