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Given the remarkable capabilities of large language models (LLMs), there has been a growing interest in evaluating their similarity to the human brain. One approach towards quantifying this similarity is by measuring how well a model…

Computation and Language · Computer Science 2024-06-24 Ebrahim Feghhi , Nima Hadidi , Bryan Song , Idan A. Blank , Jonathan C. Kao

Large language models (LLMs) can generate natural language texts for various domains and tasks, but their potential for clinical text mining, a domain with scarce, sensitive, and imbalanced medical data, is underexplored. We investigate…

Computation and Language · Computer Science 2024-02-23 Rumeng Li , Xun Wang , Hong Yu

Large Language Models (LLMs) such as GPT, LLaMA, and Claude achieve remarkable performance in text generation but remain opaque in their decision-making processes, limiting trust and accountability in high-stakes applications. We present…

Computation and Language · Computer Science 2025-10-22 Zeinab Dehghani , Mohammed Naveed Akram , Koorosh Aslansefat , Adil Khan , Yiannis Papadopoulos

The clinical utility of deep learning models for medical image segmentation is severely constrained by their inability to generalize to unseen domains. This failure is often rooted in the models learning spurious correlations between…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Tao Tang , Shijie Xu , Jionglong Su , Zhixiang Lu

Depression poses significant challenges to patients and healthcare organizations, necessitating efficient assessment methods. Existing paradigms typically focus on a patient-doctor way that overlooks multi-role interactions, such as family…

Human-Computer Interaction · Computer Science 2026-03-10 Zhiyuan Zhou , Jilong Liu , Sanwang Wang , Shijie Hao , Yanrong Guo , Richang Hong

Alzheimer's disease (AD) is the fifth-leading cause of death among Americans aged 65 and older. Screening and early detection of AD and related dementias (ADRD) are critical for timely intervention and for identifying clinical trial…

Artificial Intelligence · Computer Science 2024-05-29 Jiankun Wang , Sumyeong Ahn , Taykhoom Dalal , Xiaodan Zhang , Weishen Pan , Qiannan Zhang , Bin Chen , Hiroko H. Dodge , Fei Wang , Jiayu Zhou

Structured representations, exemplified by Abstract Meaning Representation (AMR), have long been pivotal in computational linguistics. However, their role remains ambiguous in the Large Language Models (LLMs) era. Initial attempts to…

Computation and Language · Computer Science 2025-02-21 Jiahuan Zhang , Tianheng Wang , Hanqing Wu , Ziyi Huang , Yulong Wu , Dongbai Chen , Linfeng Song , Yue Zhang , Guozheng Rao , Kaicheng Yu

Understanding the decision-making processes of neural networks is a central goal of mechanistic interpretability. In the context of Large Language Models (LLMs), this involves uncovering the underlying mechanisms and identifying the roles…

Computation and Language · Computer Science 2026-04-21 Nils Feldhus , Laura Kopf

Molecular property prediction has gained significant attention due to its transformative potential in multiple scientific disciplines. Conventionally, a molecule graph can be represented either as a graph-structured data or a SMILES text.…

Machine Learning · Computer Science 2023-07-17 Chen Qian , Huayi Tang , Zhirui Yang , Hong Liang , Yong Liu

Large language Models (LLMs), though growing exceedingly powerful, comprises of orders of magnitude less neurons and synapses than the human brain. However, it requires significantly more power/energy to operate. In this work, we propose a…

Neural and Evolutionary Computing · Computer Science 2024-02-20 Malyaban Bal , Abhronil Sengupta

This paper compares the effectiveness of traditional machine learning methods, encoder-based models, and large language models (LLMs) on the task of detecting depression and anxiety. Five Russian-language datasets were considered, each…

Computation and Language · Computer Science 2025-11-04 Gleb Kuzmin , Petr Strepetov , Maksim Stankevich , Natalia Chudova , Artem Shelmanov , Ivan Smirnov

Large Language Models (LLMs) offer a lucrative promise for scalable content moderation, including hate speech detection. However, they are also known to be brittle and biased against marginalised communities and dialects. This requires…

Computation and Language · Computer Science 2025-10-14 Ananya Malik , Kartik Sharma , Shaily Bhatt , Lynnette Hui Xian Ng

In this work we explore how language models can be employed to analyze language and discriminate between mentally impaired and healthy subjects through the perplexity metric. Perplexity was originally conceived as an information-theoretic…

Computation and Language · Computer Science 2023-02-03 Davide Colla , Matteo Delsanto , Marco Agosto , Benedetto Vitiello , Daniele Paolo Radicioni

With the rapid development of artificial intelligence, large language models (LLMs) have shown promising capabilities in mimicking human-level language comprehension and reasoning. This has sparked significant interest in applying LLMs to…

Computation and Language · Computer Science 2023-11-06 Mingze Yuan , Peng Bao , Jiajia Yuan , Yunhao Shen , Zifan Chen , Yi Xie , Jie Zhao , Yang Chen , Li Zhang , Lin Shen , Bin Dong

Large language models (LLMs) have immense potential to make information more accessible, particularly in medicine, where complex medical jargon can hinder patient comprehension of clinical notes. We developed a patient-facing tool using…

Alzheimer's disease (AD) is one the main causes of dementia in the world and the patients develop severe disability and sometime full dependence. In previous stages Mild Cognitive Impairment (MCI) produces cognitive loss but not severe…

Large language models (LLMs) are a promising venue for natural language understanding and generation. However, current LLMs are far from reliable: they are prone to generating non-factual information and, more crucially, to contradicting…

Computation and Language · Computer Science 2024-09-24 Diego Calanzone , Stefano Teso , Antonio Vergari

Over half of US adults with Alzheimer disease and related dementias remain undiagnosed, and speech-based screening offers a scalable detection approach. We compared large language model adaptation strategies for dementia detection using the…

Associative learning--forming links between co-occurring items--is fundamental to human cognition, reshaping internal representations in complex ways. Testing hypotheses on how representational changes occur in biological systems is…

Machine Learning · Computer Science 2025-10-27 Camila Kolling , Vy Ai Vo , Mariya Toneva

Fine-tuned Bidirectional Encoder Representations from Transformers (BERT)-based sequence classification models have proven to be effective for detecting Alzheimer's Disease (AD) from transcripts of human speech. However, previous research…

Computation and Language · Computer Science 2020-11-13 Aparna Balagopalan , Jekaterina Novikova