English
Related papers

Related papers: Reducing Overtreatment of Indeterminate Thyroid No…

200 papers

Lung cancer has the highest mortality rate of deadly cancers in the world. Early detection is essential to treatment of lung cancer. However, detection and accurate diagnosis of pulmonary nodules depend heavily on the experiences of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Chenglong Wang , Yun Liu , Fen Wang , Chengxiu Zhang , Yida Wang , Mei Yuan , Guang Yang

Purpose: Immunotherapies have revolutionized the landscape of cancer treatments. However, our understanding of response patterns in advanced cancers treated with immunotherapy remains limited. By leveraging routinely collected noninvasive…

The widespread adoption of CT has notably increased the number of detected lung nodules. However, current deep learning methods for classifying benign and malignant nodules often fail to comprehensively integrate global and local features,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Zhenchen Zhu , Ge Hu , Weixiong Tan , Kai Gao , Chao Sun , Zhen Zhou , Kepei Xu , Wei Han , Meixia Shang , Xiaoming Qiu , Yiqing Tan , Jinhua Wang , Zhoumeng Ying , Li Peng , Wei Song , Lan Song , Zhengyu Jin , Nan Hong , Yizhou Yu

The problem of recognizing various types of tissues present in multi-gigapixel histology images is an important fundamental pre-requisite for downstream analysis of the tumor microenvironment in a bottom-up analysis paradigm for…

Image and Video Processing · Electrical Eng. & Systems 2021-04-02 Nima Hatami , Mohsin Bilal , Nasir Rajpoot

Data is one of the essential ingredients to power deep learning research. Small datasets, especially specific to medical institutes, bring challenges to deep learning training stage. This work aims to develop a practical deep multimodal…

Machine Learning · Computer Science 2019-02-26 Faik Aydin , Maggie Zhang , Michelle Ananda-Rajah , Gholamreza Haffari

With the increasing demand for histopathological specimen examination and diagnostic reporting, Multiple Instance Learning (MIL) has received heightened research focus as a viable solution for AI-centric diagnostic aid. Recently, to improve…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Sungrae Hong , Sol Lee , Jisu Shin , Jiwon Jeong , Mun Yong Yi

Peptide receptor radionuclide therapy (PRRT) is an established treatment for metastatic neuroendocrine tumors (NETs), yet long-term disease control occurs only in a subset of patients. Predicting progression-free survival (PFS) could…

Weakly-supervised methods typically guided the pixel-wise training by comparing the predictions to single-level labels containing diverse segmentation-related information at once, but struggled to represent delicate feature differences…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Jianning Chi , Zelan Li , Huixuan Wu , Wenjun Zhang , Ying Huang

In this study, we develop a new CAD system for accurate thyroid cancer classification with emphasis on feature extraction. Prior studies have shown that thyroid texture is important for segregating the thyroid ultrasound images into…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Saurabh Saini , Kapil Ahuja , Marc C. Steinbach , Thomas Wick

Purpose: Thyroid scintigraphy plays a vital role in diagnosing a range of thyroid disorders. While deep learning classification models hold significant promise in this domain, their effectiveness is frequently compromised by limited and…

Attention-based multiple instance learning (AMIL) algorithms have proven to be successful in utilizing gigapixel whole-slide images (WSIs) for a variety of different computational pathology tasks such as outcome prediction and cancer…

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Quantitative Methods · Quantitative Biology 2025-03-14 Rajiv Krishnakumar , Julien Baglio , Frederik F. Flöther , Christian Ruiz , Stefan Habringer , Nicole H. Romano

We focus on the problem of training convolutional neural networks on gigapixel histopathology images to predict image-level targets. For this purpose, we extend Neural Image Compression (NIC), an image compression framework that reduces the…

Image and Video Processing · Electrical Eng. & Systems 2020-04-16 David Tellez , Diederik Hoppener , Cornelis Verhoef , Dirk Grunhagen , Pieter Nierop , Michal Drozdzal , Jeroen van der Laak , Francesco Ciompi

Lung cancer is the leading cause of patient mortality in the world. Early diagnosis of malignant pulmonary nodules in CT images can have a significant impact on reducing disease mortality and morbidity. In this work, we propose LMLCC-Net, a…

Image and Video Processing · Electrical Eng. & Systems 2025-11-27 Tasnia Binte Mamun , Adhora Madhuri , Nusaiba Sobir , Taufiq Hasan

Thyroid nodule segmentation is a crucial step in the diagnostic procedure of physicians and computer-aided diagnosis systems. Mostly, current studies treat segmentation and diagnosis as independent tasks without considering the correlation…

Image and Video Processing · Electrical Eng. & Systems 2023-08-30 Weihua Liu , Chaochao Lin

The rich chemical information from tissue metabolomics provides a powerful means to elaborate tissue physiology or tumor characteristics at cellular and tumor microenvironment levels. However, the process of obtaining such information…

Breast cancer is a major concern for women's health globally, with axillary lymph node (ALN) metastasis identification being critical for prognosis evaluation and treatment guidance. This paper presents a deep learning (DL) classification…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Glejdis Shkëmbi , Johanna P. Müller , Zhe Li , Katharina Breininger , Peter Schüffler , Bernhard Kainz

Accurate localization of tumor regions from hematoxylin and eosin-stained whole-slide images is fundamental for translational research including spatial analysis, molecular profiling, and tissue architecture investigation. However, deep…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Brian Isett , Rebekah Dadey , Aofei Li , Ryan C. Augustin , Kate Smith , Aatur D. Singhi , Qiangqiang Gu , Riyue Bao

Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Maryamalsadat Mahootiha , Hemin Ali Qadir , Jacob Bergsland , Ilangko Balasingham

The most prevalent form of bladder cancer is urothelial carcinoma, characterized by a high recurrence rate and substantial lifetime treatment costs for patients. Grading is a prime factor for patient risk stratification, although it suffers…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Saul Fuster , Umay Kiraz , Trygve Eftestøl , Emiel A. M. Janssen , Kjersti Engan