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Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

Background: Thyroid ultrasound is commonly performed using a combination of static images and cine clips (video recordings). However, the exact utility and impact of cine images remains unknown. This study aimed to evaluate the impact of…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Jichen Yang , Brian C. Allen , Kirti Magudia , Lisa M. Ho , Chad M. Miller , Maciej A. Mazurowski , Benjamin Wildman-Tobriner

In the field of computational pathology, the use of decision support systems powered by state-of-the-art deep learning solutions has been hampered by the lack of large labeled datasets. Until recently, studies relied on datasets in the…

Computer Vision and Pattern Recognition · Computer Science 2018-10-01 Gabriele Campanella , Vitor Werneck Krauss Silva , Thomas J. Fuchs

Accurate detection of ultrasound nodules is essential for the early diagnosis and treatment of thyroid and breast cancers. However, this task remains challenging due to irregular nodule shapes, indistinct boundaries, substantial scale…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Jingjing Wang , Zhuo Xiao , Xinning Yao , Bo Liu , Lijuan Niu , Xiangzhi Bai , Fugen Zhou

Multiple instance learning (MIL) is an effective and widely used approach for weakly supervised machine learning. In histopathology, MIL models have achieved remarkable success in tasks like tumor detection, biomarker prediction, and…

The growing interest in developing smart diagnostic systems to help medical experts process extensive data for treating incurable diseases has been notable. In particular, the challenge of identifying thyroid cancer (TC) has seen progress…

Machine Learning · Computer Science 2025-12-19 Yassine Habchi , Hamza Kheddar , Yassine Himeur , Mohamed Chahine Ghanem

Multimodal deep learning (MDL) has emerged as a transformative approach in computational pathology. By integrating complementary information from multiple data sources, MDL models have demonstrated superior predictive performance across…

Quantitative Methods · Quantitative Biology 2025-11-17 Seth Alain Chang , Muhammad Mueez Amjad , Noorul Wahab , Ethar Alzaid , Nasir Rajpoot , Adam Shephard

We present a mechanistic biomathematical model of molecular radiotherapy of thyroid disease. The general model consists of a set of differential equations describing the dynamics of different populations of thyroid cells with varying…

Medical Physics · Physics 2021-10-15 Araceli Gago-Arias , Sara Neira , Filippo Terragni , Juan Pardo-Montero

In the treatment of ovarian cancer, precise residual disease prediction is significant for clinical and surgical decision-making. However, traditional methods are either invasive (e.g., laparoscopy) or time-consuming (e.g., manual…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Xiangneng Gao , Shulan Ruan , Jun Shi , Guoqing Hu , Wei Wei

A new paradigm is beginning to emerge in Radiology with the advent of increased computational capabilities and algorithms. This has led to the ability of real time learning by computer systems of different lesion types to help the…

Multimodal deep learning has improved prognostic accuracy for brain tumours by integrating histopathology and genomic data, yet the contribution of volumetric MRI within unified survival frameworks remains unexplored. This pilot study…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Iain Swift , JingHua Ye

Prostate cancer diagnosis through MR imaging have currently relied on radiologists' interpretation, whilst modern AI-based methods have been developed to detect clinically significant cancers independent of radiologists. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2026-01-09 Xiangcen Wu , Yipei Wang , Qianye Yang , Natasha Thorley , Shonit Punwani , Veeru Kasivisvanathan , Ester Bonmati , Yipeng Hu

Ovarian tumor, as a common gynecological disease, can rapidly deteriorate into serious health crises when undetected early, thus posing significant threats to the health of women. Deep neural networks have the potential to identify ovarian…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 You Zhou , Lijiang Chen , Guangxia Cui , Wenpei Bai , Yu Guo , Shuchang Lyu , Guangliang Cheng , Qi Zhao

Liver cancer is one of the most common cancers worldwide. Due to inconspicuous texture changes of liver tumor, contrast-enhanced computed tomography (CT) imaging is effective for the diagnosis of liver cancer. In this paper, we focus on…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Yao Zhang , Jiawei Yang , Jiang Tian , Zhongchao Shi , Cheng Zhong , Yang Zhang , Zhiqiang He

Objectives We aimed to evaluate the diagnostic performance of deep learning (DL)-based radiomics models for the noninvasive prediction of isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion status in glioma patients using MRI…

Quantitative Methods · Quantitative Biology 2025-08-19 Somayeh Farahani , Marjaneh Hejazi , Mehnaz Tabassum , Antonio Di Ieva , Neda Mahdavifar , Sidong Liu

Thyroid cancer is common worldwide, with a rapid increase in prevalence across North America in recent years. While most patients present with palpable nodules through physical examination, a large number of small and medium-sized nodules…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Fatemeh Abdolali , Atefeh Shahroudnejad , Abhilash Rakkunedeth Hareendranathan , Jacob L Jaremko , Michelle Noga , Kumaradevan Punithakumar

Discriminating lung nodules as malignant or benign is still an underlying challenge. To address this challenge, radiologists need computer aided diagnosis (CAD) systems which can assist in learning discriminative imaging features…

Computer Vision and Pattern Recognition · Computer Science 2018-10-15 Maria J. M. Chuquicusma , Sarfaraz Hussein , Jeremy Burt , Ulas Bagci

Accurate detection of pulmonary nodules with high sensitivity and specificity is essential for automatic lung cancer diagnosis from CT scans. Although many deep learning-based algorithms make great progress for improving the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Jingya Liu , Liangliang Cao , Oguz Akin , Yingli Tian

The presence of MGMT promoter methylation significantly affects how well chemotherapy works for patients with Glioblastoma Multiforme (GBM). Currently, confirmation of MGMT promoter methylation relies on invasive brain tumor tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Rawan Alyahya , Asrar Alruwayqi , Atheer Alqarni , Asma Alkhaldi , Metab Alkubeyyer , Xin Gao , Mona Alshahrani