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Integrating information from multiple data sources can enable more precise, timely, and generalizable decisions. However, it is challenging to make valid causal inferences using observational data from multiple data sources. For example, in…

Methodology · Statistics 2023-02-08 Larry Han , Yige Li , Bijan A. Niknam , Jose R. Zubizarreta

The amount of biomedical data continues to grow rapidly. However, the ability to analyze these data is limited due to privacy and regulatory concerns. Machine learning approaches that require data to be copied to a single location are…

Machine Learning · Computer Science 2021-02-18 Dimitris Stripelis , Jose Luis Ambite , Pradeep Lam , Paul Thompson

A patient-centric approach to healthcare leads to an informal social network among medical professionals. This chapter presents a research framework to: identify the collaboration structure among physicians that is effective and efficient…

Social and Information Networks · Computer Science 2015-09-28 Uma Srinivasan , Shahadat Uddin

The use of collaborative and decentralized machine learning techniques such as federated learning have the potential to enable the development and deployment of clinical risk predictions models in low-resource settings without requiring…

Machine Learning · Computer Science 2019-11-15 Stephen R. Pfohl , Andrew M. Dai , Katherine Heller

There is a compelling demand for the data integration and exploitation of heterogeneous biomedical information for improved clinical practice, medical research, and personalised healthcare across the EU. The area of paediatric information…

Databases · Computer Science 2014-02-25 Richard McClatchey

Scientific data management is at a critical juncture, driven by exponential data growth, increasing cross-domain dependencies, and a severe reproducibility crisis in modern research. Traditional centralized data management approaches are…

Databases · Computer Science 2025-04-30 Sebastian Beyvers , Jannis Hochmuth , Lukas Brehm , Maria Hansen , Alexander Goesmann , Frank Förster

Integrating Electronic Health Records (EHR) and the application of machine learning present opportunities for enhancing the accuracy and accessibility of data-driven diabetes prediction. In particular, developing data-driven machine…

Computational Engineering, Finance, and Science · Computer Science 2024-08-23 Guojun Tang , Jason E. Black , Tyler S. Williamson , Steve H. Drew

The real-world implementation of federated learning is complex and requires research and development actions at the crossroad between different domains ranging from data science, to software programming, networking, and security. While…

With the rapid development of computing technology, wearable devices such as smart phones and wristbands make it easy to get access to people's health information including activities, sleep, sports, etc. Smart healthcare achieves great…

Machine Learning · Computer Science 2021-05-12 Yiqiang Chen , Jindong Wang , Chaohui Yu , Wen Gao , Xin Qin

The use of multi-centric analyses is crucial for obtaining sufficient sample sizes and representative clinical populations in experimental studies. In this setting, data harmonization techniques are typically employed to address systematic…

Quantitative Methods · Quantitative Biology 2026-01-22 Santiago Silva , Ghiles Reguig , Neil P Oxtoby , Andre Altmann , Marco Lorenzi

Personalized medication aims to tailor healthcare to individual patient characteristics. However, the heterogeneity of patient data across healthcare systems presents significant challenges to achieving accurate and effective personalized…

Artificial Intelligence · Computer Science 2024-12-10 Jiechao Gao , Yuangang Li

This paper presents a perspective on the Healthgrid initiative which involves European projects deploying pioneering applications of grid technology in the health sector. In the last couple of years, several grid projects have been funded…

Databases · Computer Science 2016-11-18 V. Breton , A. E. Solomonides , R. H. McClatchey

Protecting patient privacy remains a fundamental barrier to scaling machine learning across healthcare institutions, where centralizing sensitive data is often infeasible due to ethical, legal, and regulatory constraints. Federated learning…

Machine Learning · Computer Science 2026-03-24 Vagish Kumar , Syed Bahauddin Alam , Souvik Chakraborty

Record linkage means linking data from multiple sources. This approach enables the answering of scientific questions that cannot be addressed using single data sources due to limited variables. The potential of linked data for health…

Digitized, networked healthcare promises earlier detection, precision therapeutics, and continuous care; yet, it also expands the surface for privacy loss and compliance risk. We argue for a shift from siloed, application-specific…

Cryptography and Security · Computer Science 2026-01-09 M. Amin Rahimian , Benjamin Panny , James Joshi

Modern Internet of Things (IoT) applications generate enormous amounts of data, making data-driven machine learning essential for developing precise and reliable statistical models. However, data is often stored in silos, and strict…

Cryptography and Security · Computer Science 2024-06-11 Shinu M. Rajagopal , Supriya M. , Rajkumar Buyya

This paper presents a sandbox study proposal focused on the distributed processing of personal health data within the Vinnova-funded SARDIN project. The project aims to develop the Health Data Bank (H\"alsodatabanken in Swedish), a secure…

Cryptography and Security · Computer Science 2025-01-27 Rickard Brännvall , Hanna Svensson , Kannaki Kaliyaperumal , Håkan Burden , Susanne Stenberg

The rapid growth of data from edge devices has catalyzed the performance of machine learning algorithms. However, the data generated resides at client devices thus there are majorly two challenge faced by traditional machine learning…

Machine Learning · Computer Science 2024-07-15 Shivam Gupta , Tarushi , Tsering Wangzes , Shweta Jain

Managing personal health data is a challenge in today's fragmented and institution-centric healthcare ecosystem. Individuals often lack meaningful control over their medical records, which are scattered across incompatible systems and…

Multimedia · Computer Science 2026-02-24 Sujaya Maiyya , Shantanu Sharma , Avinash Kumar

This paper proposes a data privacy protection framework based on federated learning, which aims to realize effective cross-domain data collaboration under the premise of ensuring data privacy through distributed learning. Federated learning…

Machine Learning · Computer Science 2025-04-02 Yiwei Zhang , Jie Liu , Jiawei Wang , Lu Dai , Fan Guo , Guohui Cai