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The widespread adoption of electronic health records has created new opportunities for translational clinical research, yet this promise remains constrained by fragmented data across privacy-siloed institutions and substantial heterogeneity…

With increasing concerns over privacy in healthcare, especially for sensitive medical data, this research introduces a federated learning framework that combines local differential privacy and secure aggregation using Secure Multi-Party…

Machine Learning · Computer Science 2024-12-03 Mohamad Haj Fares , Ahmed Mohamed Saad Emam Saad

Digital twin (DT) technology holds immense potential for transforming healthcare systems through real-time monitoring, predictive analysis, and agile interventions to support various decision-making needs. However, its successful…

Computers and Society · Computer Science 2025-08-05 Md Doulotuzzaman Xames , Taylan G. Topcu

There has been much research activity in recent times about providing the data infrastructures needed for the provision of personalised healthcare. In particular the requirement of integrating multiple, potentially distributed,…

Databases · Computer Science 2008-12-16 Andrew Branson , Tamas Hauer , Richard McClatchey , Dmitry Rogulin , Jetendr Shamdasani

Privacy data protection in the medical field poses challenges to data sharing, limiting the ability to integrate data across hospitals for training high-precision auxiliary diagnostic models. Traditional centralized training methods are…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Tian Bowen , Xu Zhengyang , Yin Zhihao , Wang Jingying , Yue Yutao

The increased availability of medical data has significantly impacted healthcare by enabling the application of machine / deep learning approaches in various instances. However, medical datasets are usually small and scattered across…

Capabilities to exchange health information are critical to accelerate discovery and its diffusion to healthcare practice. However, the same ethical and legal policies that protect privacy hinder these data exchanges, and the issues…

Computers and Society · Computer Science 2016-12-16 Hanna Suominen , Henning Müller , Lucila Ohno-Machado , Sanna Salanterä , Günter Schreier , Leif Hanlen

Collaboration across institutional boundaries is widespread and increasing today. It depends on federations sharing data that often have governance rules or external regulations restricting their use. However, the handling of data…

Databases · Computer Science 2021-10-05 Rui Zhao , Malcolm Atkinson , Petros Papapanagiotou , Federica Magnoni , Jacques Fleuriot

At this moment, databanks worldwide contain brain images of previously unimaginable numbers. Combined with developments in data science, these massive data provide the potential to better understand the genetic underpinnings of brain…

Machine Learning · Statistics 2025-01-30 Santiago Silva , Boris Gutman , Eduardo Romero , Paul M Thompson , Andre Altmann , Marco Lorenzi

Health information is generally fragmented across silos. Though it is technically feasible to unite data for analysis in a manner that underpins a rapid learning healthcare system, privacy concerns and regulatory barriers limit data…

Machine Learning · Computer Science 2020-12-10 Dianbo Liu , Kathe Fox , Griffin Weber , Tim Miller

With the growth of machine learning techniques, privacy of data of users has become a major concern. Most of the machine learning algorithms rely heavily on large amount of data which may be collected from various sources. Collecting these…

Machine Learning · Computer Science 2023-11-17 Mahfuzur Rahman Chowdhury , Muhammad Ibrahim

To address the multidimensional nature of health-related questions, advances in health research often require integrating information from various data sources within statistical analyses. When complementary information pertaining to the…

The healthcare system collects extensive data, encompassing patient administrative information, clinical measurements, and home-monitored health metrics. To support informed decision-making in patient care and treatment management, it is…

Human-Computer Interaction · Computer Science 2024-09-18 Faisal Zaki Roshan , Abhishek Ahuja , Fateme Rajabiyazdi

The age of big data has fueled expectations for accelerating learning. The availability of large data sets enables researchers to achieve more powerful statistical analyses and enhances the reliability of conclusions, which can be based on…

Methodology · Statistics 2023-08-22 Ori Becher , Mira Marcus-Kalish , David M. Steinberg

Federated Learning (FL) offers a promising approach for training clinical AI models without centralizing sensitive patient data. However, its real-world adoption is hindered by challenges related to privacy, resource constraints, and…

The growing availability of clinical data has increased the use of machine learning, yet centralized data aggregation is often infeasible for sensitive health information. Federated Learning (FL) offers a distributed alternative, but its…

Machine Learning · Computer Science 2026-05-26 Anisa Halimi , Liubov Nedoshivina , Kieran Fraser , Stefano Braghin

As deep learning have been applied in a clinical context, privacy concerns have increased because of the collection and processing of a large amount of personal data. Recently, federated learning (FL) has been suggested to protect personal…

Machine Learning · Computer Science 2020-05-26 GeunHyeong Lee , Soo-Yong Shin

Clinicians are interested in better understanding complex diseases, such as cancer or rare diseases, so they need to produce and exchange data to mutualize sources and join forces. To do so and ensure privacy, a natural way consists in…

Databases · Computer Science 2025-09-29 Nelly Barret , Anna Bernasconi , Boris Bikbov , Pietro Pinoli

Recently, many innovations have been experienced in healthcare by rapidly growing Internet-of-Things (IoT) technology that provides significant developments and facilities in the health sector and improves daily human life. The IoT bridges…

Cryptography and Security · Computer Science 2021-09-30 Kevser Şahinbaş , Ferhat Ozgur Catak

The rapid evolution of artificial intelligence (AI) technologies holds transformative potential for the healthcare sector. In critical situations requiring immediate decision-making, healthcare professionals can leverage machine learning…