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Background: More than 80% of U.S. cancer care is delivered in community settings, where survival remains worse than at academic centers. Clinicians must integrate genomics, staging, radiology, pathology, and changing guidelines, creating…

Beyond 5G networks provide solutions for next-generation communications, especially digital twins networks (DTNs) have gained increasing popularity for bridging physical space and digital space. However, current DTNs networking frameworks…

Networking and Internet Architecture · Computer Science 2023-12-19 Yang Hong , Jun Wu , Rosario Morello

Digital twin (DT) techniques have been proposed for the autonomous operation and lifecycle management of next-generation optical networks. To fully utilize potential capacity and accommodate dynamic services, the DT must dynamically update…

Digital Twin was introduced over a decade ago, as an innovative all-encompassing tool, with perceived benefits including real-time monitoring, simulation and forecasting. However, the theoretical framework and practical implementations of…

Machine Learning · Computer Science 2020-12-07 Angira Sharma , Edward Kosasih , Jie Zhang , Alexandra Brintrup , Anisoara Calinescu

The report describes the discussions from the Workshop on Mathematical Opportunities in Digital Twins (MATH-DT) from December 11-13, 2023, George Mason University. It illustrates that foundational Mathematical advances are required for…

Optimization and Control · Mathematics 2024-03-25 Harbir Antil

With the fast evolving of cloud computing and artificial intelligence (AI), the concept of digital twin (DT) has recently been proposed and finds broad applications in industrial Internet, IoT, smart city, etc. The DT builds a mirror…

Networking and Internet Architecture · Computer Science 2021-05-18 Tom H. Luan , Ruhan Liu , Longxiang Gao , Rui Li , Haibo Zhou

This paper presents a novel design of a multi-agent system framework that applies large language models (LLMs) to automate the parametrization of simulation models in digital twins. This framework features specialized LLM agents tasked with…

Artificial Intelligence · Computer Science 2024-07-23 Yuchen Xia , Daniel Dittler , Nasser Jazdi , Haonan Chen , Michael Weyrich

The digital transformation of modern cities by integrating advanced information, communication, and computing technologies has marked the epoch of data-driven smart city applications for efficient and sustainable urban management. Despite…

Artificial Intelligence · Computer Science 2024-08-08 Haowen Xu , Femi Omitaomu , Soheil Sabri , Sisi Zlatanova , Xiao Li , Yongze Song

Cancer has relational information residing at varying scales, modalities, and resolutions of the acquired data, such as radiology, pathology, genomics, proteomics, and clinical records. Integrating diverse data types can improve the…

Machine Learning · Computer Science 2024-07-29 Asim Waqas , Aakash Tripathi , Ravi P. Ramachandran , Paul Stewart , Ghulam Rasool

A digital twin is a surrogate model that has the main feature to mirror the original process behavior. Associating the dynamical process with a digital twin model of reduced complexity has the significant advantage to map the dynamics with…

Numerical Analysis · Mathematics 2024-03-19 Diana Alina Bistrian , Omer San , Ionel Michael Navon

This paper presents the first probabilistic Digital Twin of operational en route airspace, developed for the London Area Control Centre. The Digital Twin is intended to support the development and rigorous human-in-the-loop evaluation of AI…

In the era of Internet of Things (IoT), Digital Twin (DT) is envisioned to empower various areas as a bridge between physical objects and the digital world. Through virtualization and simulation techniques, multiple functions can be…

Machine Learning · Computer Science 2023-07-14 Ziru Zhang , Xuling Zhang , Guangzhi Zhu , Yuyang Wang , Pan Hui

Digital Twins (DT) facilitate monitoring and reasoning processes in cyber-physical systems. They have progressively gained popularity over the past years because of intense research activity and industrial advancements. Cognitive Twins is a…

Artificial Intelligence · Computer Science 2023-12-22 Erkan Karabulut , Salvatore F. Pileggi , Paul Groth , Victoria Degeler

Digital twins (DT) are increasingly used in healthcare to model patients, processes, and physiological systems. While recent solutions leverage visualization, visual analytics, and user interaction, these systems rarely incorporate…

Human-Computer Interaction · Computer Science 2025-09-09 Mariia Ershova , Graziano Blasilli

This paper introduces a novel approach to integrating large language model (LLM) agents into automated production systems, aimed at enhancing task automation and flexibility. We organize production operations within a hierarchical framework…

Artificial Intelligence · Computer Science 2024-07-12 Yuchen Xia , Jize Zhang , Nasser Jazdi , Michael Weyrich

Lung cancer remains one of the most prevalent and fatal diseases worldwide, demanding accurate and timely diagnosis and treatment. Recent advancements in large AI models have significantly enhanced medical image understanding and clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Jiachen Zhong , Yiting Wang , Di Zhu , Ziwei Wang

Digital Twins (DTs) are becoming increasingly vital for future industrial applications, enhancing monitoring, control, and optimization of physical assets. This enhancement is made possible by integrating various Digital Models (DMs) within…

Generative AI (GenAI), exemplified by Large Language Models (LLMs) such as OpenAI's ChatGPT, is revolutionizing various fields. Central to this transformation is Data Center Networking (DCN), which not only provides the computational power…

Networking and Internet Architecture · Computer Science 2024-09-17 Yinqiu Liu , Hongyang Du , Dusit Niyato , Jiawen Kang , Zehui Xiong , Yonggang Wen , Dong In Kim

6G networks are envisioned to enable a wide range of applications, such as autonomous vehicles and smart cities. However, this rapid expansion of network topologies makes the management of 6G wireless networks more complex and leads to…

Networking and Internet Architecture · Computer Science 2024-11-22 Kubra Duran , Lal Verda Cakir , Mehmet Ozdem , Kerem Gursu , Berk Canberk

Current neural interfaces such as brain-computer interfaces (BCIs) face several fundamental challenges, including frequent recalibration due to neuroplasticity and session-to-session variability, real-time processing latency, limited…

Human-Computer Interaction · Computer Science 2026-01-06 Mohammad Mahdi Habibi Bina , Sepideh Baghernezhad , Mohammad Reza Daliri , Mohammad Hassan Moradi