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The digital twin concept represents an appealing opportunity to advance condition-based and predictive maintenance paradigms for civil engineering systems, thus allowing reduced lifecycle costs, increased system safety, and increased system…

Numerical Analysis · Mathematics 2023-11-10 Matteo Torzoni , Marco Tezzele , Stefano Mariani , Andrea Manzoni , Karen E. Willcox

Digital twins are models of real-world systems that can simulate their dynamics in response to potential actions. In complex settings, the state and action variables, and available data and knowledge relevant to a system can constantly…

Computation and Language · Computer Science 2025-07-23 Harry Amad , Nicolás Astorga , Mihaela van der Schaar

Artificial intelligence (AI) has long promised to improve energy management in smart grids by enhancing situational awareness and supporting more effective decision-making. While traditional machine learning has demonstrated notable results…

Machine Learning · Computer Science 2025-06-10 Gabriel Antonesi , Tudor Cioara , Ionut Anghel , Vasilis Michalakopoulos , Elissaios Sarmas , Liana Toderean

A digital twin can be defined as an adaptive model of a complex physical system. Recent advances in computational pipelines, multiphysics solvers, artificial intelligence, big data cybernetics, data processing and management tools bring the…

Signal Processing · Electrical Eng. & Systems 2019-10-07 Adil Rasheed , Omer San , Trond Kvamsdal

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

Modern organizations necessitate continuous business processes improvement to maintain efficiency, adaptability, and competitiveness. In the last few years, the Internet of Things, via the deployment of sensors and actuators, has heavily…

Insufficient data volume and quality are particularly pressing challenges in the adoption of modern subsymbolic AI. To alleviate these challenges, AI simulation uses virtual training environments in which AI agents can be safely and…

Artificial Intelligence · Computer Science 2025-09-01 Xiaoran Liu , Istvan David

Clinical decision-making is inherently complex, often influenced by cognitive biases, incomplete information, and case ambiguity. Large Language Models (LLMs) have shown promise as tools for supporting clinical decision-making, yet their…

Machine Learning · Computer Science 2025-07-10 Burcu Sayin , Ipek Baris Schlicht , Ngoc Vo Hong , Sara Allievi , Jacopo Staiano , Pasquale Minervini , Andrea Passerini

Recently, significant efforts have been made to create Health Digital Twins (HDTs), digital twins for clinical applications. Heart modeling is one of the fastest-growing fields, which favors the effective application of HDTs. The clinical…

Neurons and Cognition · Quantitative Biology 2024-03-21 Zofia Rudnicka , Klaudia Proniewska , Mark Perkins , Agnieszka Pregowska

Although digital twins have recently emerged as a clear alternative for reliable asset representations, most of the solutions and tools available for the development of digital twins are tailored to specific environments. Furthermore,…

Software Engineering · Computer Science 2023-01-16 Julia Robles , Cristian Martín , Manuel Díaz

The application of large language models (LLMs) in clinical decision support faces significant challenges of "tunnel vision" and diagnostic hallucinations present in their processing unstructured electronic health records (EHRs). To address…

Artificial Intelligence · Computer Science 2026-04-28 Zhiqi Lv , Duofan Tu , Jun Li , Mingyue Zhao , Heqin Zhu , Wenliang Li , Shaohua Kevin Zhou

The evolution of network virtualization and native artificial intelligence (AI) paradigms have conceptualized the vision of future wireless networks as a comprehensive entity operating in whole over a digital platform, with smart…

Artificial Intelligence · Computer Science 2023-03-30 Lina Bariah , Merouane Debbah

We articulate the design imperatives for machine-learning based digital twins for nonlinear dynamical systems subject to external driving, which can be used to monitor the ``health'' of the target system and anticipate its future collapse.…

Adaptation and Self-Organizing Systems · Physics 2022-10-13 Ling-Wei Kong , Yang Weng , Bryan Glaz , Mulugeta Haile , Ying-Cheng Lai

Digital Twin, as an emerging technology related to Cyber-Physical Systems (CPS) and Internet of Things (IoT), has attracted increasing attentions during the past decade. Conceptually, a Digital Twin is a digital replica of a physical entity…

Systems and Control · Electrical Eng. & Systems 2021-05-05 Ziran Wang , Kyungtae Han , Prashant Tiwari

The design and operation of systems are conventionally viewed as a sequential decision-making process that is informed by data from physical experiments and simulations. However, the integration of these high-dimensional and heterogeneous…

Applications · Statistics 2025-03-04 Anton van Beek , Vispi Karkaria , Wei Chen

Each year, the lack of efficient data standardization and interoperability in cancer care contributes to the severe lack of timely and effective diagnosis, while constantly adding to the burden of cost, with cancer costs nationally reaching…

Machine Learning · Computer Science 2024-10-29 Aarsh Shekhar , Mincheol Kim

Digital Twin (DT) technology has emerged as a transformative approach in healthcare, but its application in personalized patient care remains limited. This paper aims to present a practical implementation of DT in the management of chronic…

Quantitative Methods · Quantitative Biology 2025-07-17 Javad M Alizadeh , Mukesh K Patel , Huanmei Wu

Large language models (LLMs) have shown remarkable progress in encoding clinical knowledge and responding to complex medical queries with appropriate clinical reasoning. However, their applicability in subspecialist or complex medical…

Digital twins promise a better understanding and use of complex systems. To this end, they represent these systems at their runtime and may interact with them to control their processes. Software engineering is a wicked challenge in which…

Software Engineering · Computer Science 2025-10-08 Robin Kimmel , Judith Michael , Andreas Wortmann , Jingxi Zhang

In today's networked world, Digital Twin Networks (DTNs) are revolutionizing how we understand and optimize physical networks. These networks, also known as 'Digital Twin Networks (DTNs)' or 'Networks Digital Twins (NDTs),' encompass many…

Networking and Internet Architecture · Computer Science 2025-01-28 Sarah Al-Shareeda , Khayal Huseynov , Lal Verda Cakir , Craig Thomson , Mehmet Ozdem , Berk Canberk
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