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In the past years, deep learning has seen an increase in usage in the domain of histopathological applications. However, while these approaches have shown great potential, in high-risk environments deep learning models need to be able to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Hendrik A. Mehrtens , Alexander Kurz , Tabea-Clara Bucher , Titus J. Brinker

Unsupervised anomaly detection (AD) is a challenging task in realistic applications. Recently, there is an increasing trend to detect anomalies with deep neural networks (DNN). However, most popular deep AD detectors cannot protect the…

Machine Learning · Computer Science 2022-05-31 Shaoshen Wang , Yanbin Liu , Ling Chen , Chengqi Zhang

Unsupervised Anomaly Detection (UAD) techniques aim to identify and localize anomalies without relying on annotations, only leveraging a model trained on a dataset known to be free of anomalies. Diffusion models learn to modify inputs $x$…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Sergio Naval Marimont , Matthew Baugh , Vasilis Siomos , Christos Tzelepis , Bernhard Kainz , Giacomo Tarroni

Known for their impressive performance in generative modeling, diffusion models are attractive candidates for density-based anomaly detection. This paper investigates different variations of diffusion modeling for unsupervised and…

Machine Learning · Computer Science 2026-05-11 Victor Livernoche , Vineet Jain , Yashar Hezaveh , Siamak Ravanbakhsh

In recent years, deep learning has rapidly become a method of choice for the segmentation of medical images. Deep Neural Network (DNN) architectures such as UNet have achieved state-of-the-art results on many medical datasets. To further…

Computer Vision and Pattern Recognition · Computer Science 2021-04-13 Truong Dang , Tien Thanh Nguyen , John McCall , Eyad Elyan , Carlos Francisco Moreno-García

In a given classification task, the accuracy of the learner is often hampered by finiteness of the training set, high-dimensionality of the feature space and severe overlap between classes. In the context of interpretable learners, with…

Machine Learning · Computer Science 2025-04-03 Marco Canducci , Lida Abdi , Alessandro Prete , Roland J. Veen , Michael Biehl , Wiebke Arlt , Peter Tino

Diffusion models (DMs) have emerged as a powerful class of generative AI models, showing remarkable potential in anomaly detection (AD) tasks across various domains, such as cybersecurity, fraud detection, healthcare, and manufacturing. The…

Machine Learning · Computer Science 2025-02-28 Jing Liu , Zhenchao Ma , Zepu Wang , Chenxuanyin Zou , Jiayang Ren , Zehua Wang , Liang Song , Bo Hu , Yang Liu , Victor C. M. Leung

Detecting anomalies in multivariate time series is essential for monitoring complex industrial systems, where high dimensionality, limited labeled data, and subtle dependencies between sensors cause significant challenges. This paper…

Machine Learning · Computer Science 2025-11-18 Bahareh Golchin , Banafsheh Rekabdar

Deformable medical image registration is a fundamental task in medical image analysis. While deep learning-based methods have demonstrated superior accuracy and computational efficiency compared to traditional techniques, they often…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Ahsan Raza Siyal , Markus Haltmeier , Ruth Steiger , Malik Galijasevic , Elke Ruth Gizewski , Astrid Ellen Grams

Early detection of anomalies in medical images such as brain MRI is highly relevant for diagnosis and treatment of many conditions. Supervised machine learning methods are limited to a small number of pathologies where there is good…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Alexander Frotscher , Jaivardhan Kapoor , Thomas Wolfers , Christian F. Baumgartner

Automated visual inspection in medical-device manufacturing faces unique challenges, including extremely low defect rates, limited annotated data, hardware restrictions on production lines, and the need for validated, explainable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Julio Zanon Diaz , Georgios Siogkas , Peter Corcoran

Learning discriminative features for effectively separating abnormal events from normality is crucial for weakly supervised video anomaly detection (WS-VAD) tasks. Existing approaches, both video and segment-level label oriented, mainly…

Computer Vision and Pattern Recognition · Computer Science 2023-02-13 Hang Zhou , Junqing Yu , Wei Yang

Deep neural networks lack interpretability and tend to be overconfident, which poses a serious problem in safety-critical applications like autonomous driving, medical imaging, or machine vision tasks with high demands on reliability.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Steven Landgraf , Kira Wursthorn , Markus Hillemann , Markus Ulrich

Generative models have demonstrated significant success in anomaly detection and segmentation over the past decade. Recently, diffusion models have emerged as a powerful alternative, outperforming previous approaches such as GANs and VAEs.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Mehrdad Moradi , Marco Grasso , Bianca Maria Colosimo , Kamran Paynabar

Medical image segmentation is an actively studied task in medical imaging, where the precision of the annotations is of utter importance towards accurate diagnosis and treatment. In recent years, the task has been approached with various…

Image and Video Processing · Electrical Eng. & Systems 2022-12-22 Mariana-Iuliana Georgescu , Radu Tudor Ionescu , Andreea-Iuliana Miron

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Many anomaly detection approaches, especially deep learning methods, have been recently developed to identify abnormal image morphology by only employing normal images during training. Unfortunately, many prior anomaly detection methods…

This paper presents a fast, principled approach for detecting anomalous and out-of-distribution (OOD) samples in deep neural networks (DNN). We propose the application of linear statistical dimensionality reduction techniques on the…

Machine Learning · Computer Science 2022-03-22 Ibrahima J. Ndiour , Nilesh A. Ahuja , Omesh Tickoo

Reconstruction-based approaches have achieved remarkable outcomes in anomaly detection. The exceptional image reconstruction capabilities of recently popular diffusion models have sparked research efforts to utilize them for enhanced…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Haoyang He , Jiangning Zhang , Hongxu Chen , Xuhai Chen , Zhishan Li , Xu Chen , Yabiao Wang , Chengjie Wang , Lei Xie

Assessing the quality of aleatoric uncertainty estimates from uncertainty quantification (UQ) deep learning methods is important in scientific contexts, where uncertainty is physically meaningful and important to characterize and interpret…

Machine Learning · Computer Science 2024-11-14 Rebecca Nevin , Aleksandra Ćiprijanović , Brian D. Nord
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