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The problem of domain generalization is to learn from multiple training domains, and extract a domain-agnostic model that can then be applied to an unseen domain. Domain generalization (DG) has a clear motivation in contexts where there are…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 Da Li , Yongxin Yang , Yi-Zhe Song , Timothy M. Hospedales

Deep Learning (DL) approaches have been providing state-of-the-art performance in different modalities in the field of medical imagining including Digital Pathology Image Analysis (DPIA). Out of many different DL approaches, Deep…

Computer Vision and Pattern Recognition · Computer Science 2019-04-22 Md Zahangir Alom , Theus Aspiras , Tarek M. Taha , Vijayan K. Asari , TJ Bowen , Dave Billiter , Simon Arkell

Deep learning is expected to aid pathologists by automating tasks such as tumour segmentation. We aimed to develop one universal tumour segmentation model for histopathological images and examine its performance in different cancer types.…

The generalization of deep neural networks to unknown domains is a major challenge despite their tremendous progress in recent years. For this reason, the dynamic area of domain generalization (DG) has emerged. In contrast to unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Manuel Schwonberg , Hanno Gottschalk

Deep learning techniques have proven high accuracy for identifying melanoma in digitised dermoscopic images. A strength is that these methods are not constrained by features that are pre-defined by human semantics. A down-side is that it is…

Machine Learning · Computer Science 2019-11-13 Kyle Young , Gareth Booth , Becks Simpson , Reuben Dutton , Sally Shrapnel

The emergence of pathology foundation models has revolutionized computational histopathology, enabling highly accurate, generalized whole-slide image analysis for improved cancer diagnosis, and prognosis assessment. While these models show…

Computational pathology can lead to saving human lives, but models are annotation hungry and pathology images are notoriously expensive to annotate. Self-supervised learning has shown to be an effective method for utilizing unlabeled data,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Mingu Kang , Heon Song , Seonwook Park , Donggeun Yoo , Sérgio Pereira

Skin cancer can be life-threatening if not diagnosed early, a prevalent yet preventable disease. Globally, skin cancer is perceived among the finest prevailing cancers and millions of people are diagnosed each year. For the allotment of…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Mohammad Tahmid Noor , B. M. Shahria Alam , Tasmiah Rahman Orpa , Shaila Afroz Anika , Mahjabin Tasnim Samiha , Fahad Ahammed

Skin cancer is one of the most prevalent and deadly forms of cancer worldwide, highlighting the critical importance of early detection and diagnosis in improving patient outcomes. Deep learning (DL) has shown significant promise in…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Runhao Liu , Ziming Chen , Guangzhen Yao , Peng Zhang

With the rapid development of computational pathology, many AI-assisted diagnostic tasks have emerged. Cellular nuclei segmentation can segment various types of cells for downstream analysis, but it relies on predefined categories and lacks…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Chunlin Zhong , Shuang Hao , Junhua Wu , Xiaona Chang , Jiwei Jiang , Xiu Nie , He Tang , Xiang Bai

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Computer-aided detection systems based on deep learning have shown great potential in breast cancer detection. However, the lack of domain generalization of artificial neural networks is an important obstacle to their deployment in changing…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Lidia Garrucho , Kaisar Kushibar , Socayna Jouide , Oliver Diaz , Laura Igual , Karim Lekadir

During the past decade, deep neural networks have led to fast-paced progress and significant achievements in computer vision problems, for both academia and industry. Yet despite their success, state-of-the-art image classification…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Aristotelis Ballas , Christos Diou

Deep learning has been increasingly incorporated into various computational pathology applications to improve its efficiency, accuracy, and robustness. Although successful, most previous approaches for image classification have crucial…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Anh Tien Nguyen , Jin Tae Kwak

Ki67 is a significant biomarker in the diagnosis and prognosis of cancer, whose index can be evaluated by quantifying its expression in Ki67 immunohistochemistry (IHC) stained images. However, quantitative analysis on multi-source Ki67…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Jiatong Cai , Chenglu Zhu , Can Cui , Honglin Li , Tong Wu , Shichuan Zhang , Lin Yang

Deep learning (DL) models have received particular attention in medical imaging due to their promising pattern recognition capabilities. However, Deep Neural Networks (DNNs) require a huge amount of data, and because of the lack of…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Donya Khaledyan , AmirReza Tajally , Ali Sarkhosh , Afshar Shamsi , Hamzeh Asgharnezhad , Abbas Khosravi , Saeid Nahavandi

Despite the ever-increasing interest in applying deep learning (DL) models to medical imaging, the typical scarcity and imbalance of medical datasets can severely impact the performance of DL models. The generation of synthetic data that…

Image and Video Processing · Electrical Eng. & Systems 2023-04-03 Pouria Rouzrokh , Bardia Khosravi , Shahriar Faghani , Mana Moassefi , Sanaz Vahdati , Bradley J. Erickson

The escalating global cancer burden underscores the critical need for precise diagnostic tools in oncology. This research employs deep learning to enhance lesion segmentation in PET/CT imaging, utilizing a dataset of 900 whole-body…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Jiayi Liu , Qiaoyi Xue , Youdan Feng , Tianming Xu , Kaixin Shen , Chuyun Shen , Yuhang Shi

In search of robust and generalizable machine learning models, Domain Generalization (DG) has gained significant traction during the past few years. The goal in DG is to produce models which continue to perform well when presented with data…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Aristotelis Ballas , Christos Diou