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In this paper, we present our submission to the LUMIR25 task of Learn2Reg 2025, which ranked 1st overall on the test set. Extended from LUMIR24, this year's task focuses on zero-shot registration under domain shifts (e.g., high-field MRI,…

Image and Video Processing · Electrical Eng. & Systems 2026-02-24 Hengjie Liu , Yimeng Dou , Di Xu , Xinyi Fu , Dan Ruan , Ke Sheng

Masked image modelling (MIM) is a powerful self-supervised representation learning paradigm, whose potential has not been widely demonstrated in medical image analysis. In this work, we show the capacity of MIM to capture rich semantic…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Piotr Wójcik , Hussein Naji , Adrian Simon , Reinhard Büttner , Katarzyna Bożek

Increased levels of tumor infiltrating lymphocytes (TILs) in cancer tissue indicate favourable outcomes in many types of cancer. Manual quantification of immune cells is inaccurate and time consuming for pathologists. Our aim is to leverage…

Registration of pre-operative and post-recurrence brain images is often needed to evaluate the effectiveness of brain gliomas treatment. While recent deep learning-based deformable registration methods have achieved remarkable success with…

Image and Video Processing · Electrical Eng. & Systems 2022-06-09 Tony C. W. Mok , Albert C. S. Chung

Deep learning has emerged as a strong alternative for classical iterative methods for deformable medical image registration, where the goal is to find a mapping between the coordinate systems of two images. Popular classical image…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Joel Honkamaa , Pekka Marttinen

Retinal image registration plays an important role in the ophthalmological diagnosis process. Since there exist variances in viewing angles and anatomical structures across different retinal images, keypoint-based approaches become the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Yepeng Liu , Baosheng Yu , Tian Chen , Yuliang Gu , Bo Du , Yongchao Xu , Jun Cheng

Multi-instance learning is common for computer vision tasks, especially in biomedical image processing. Traditional methods for multi-instance learning focus on designing feature aggregation methods and multi-instance classifiers, where the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-18 Yanlun Tu , Houchao Lei , Wei Long , Yang Yang

Cell detection, segmentation and classification are essential for analyzing tumor microenvironments (TME) on hematoxylin and eosin (H&E) slides. Existing methods suffer from poor performance on understudied cell types (rare or not present…

Diffeomorphic deformable multi-modal image registration is a challenging task which aims to bring images acquired by different modalities to the same coordinate space and at the same time to preserve the topology and the invertibility of…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Vasiliki Sideri-Lampretsa , Georgios Kaissis , Daniel Rueckert

Image Registration (IR) is the process of aligning two (or more) images of the same scene taken at different times, different viewpoints and/or by different sensors. It is an important, crucial step in various image analysis tasks where…

Computer Vision and Pattern Recognition · Computer Science 2017-11-21 Sarit Chicotay , Eli David , Nathan S. Netanyahu

Image registration is fundamental in medical imaging applications, such as disease progression analysis or radiation therapy planning. The primary objective of image registration is to precisely capture the deformation between two or more…

Image and Video Processing · Electrical Eng. & Systems 2024-12-23 Anna Reithmeir , Veronika Spieker , Vasiliki Sideri-Lampretsa , Daniel Rueckert , Julia A. Schnabel , Veronika A. Zimmer

Registration is widely used in image-guided therapy and image-guided surgery to estimate spatial correspondences between organs of interest between planning and treatment images. However, while high-quality computed tomography (CT) images…

Image and Video Processing · Electrical Eng. & Systems 2022-03-11 Lin Tian , Connor Puett , Peirong Liu , Zhengyang Shen , Stephen R. Aylward , Yueh Z. Lee , Marc Niethammer

Deformable image registration is able to achieve fast and accurate alignment between a pair of images and thus plays an important role in many medical image studies. The current deep learning (DL)-based image registration approaches…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Xinke Ma , Yibo Yang , Yong Xia , Dacheng Tao

Image registration is a widely-used technique in analysing large scale datasets that are captured through various imaging modalities and techniques in biomedical imaging such as MRI, X-Rays, etc. These datasets are typically collected from…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Hassan Mahmood , Asim Iqbal , Syed Mohammed Shamsul Islam

Hyperspectral remote sensing images (HSIs) usually have high spectral resolution and low spatial resolution. Conversely, multispectral images (MSIs) usually have low spectral and high spatial resolutions. The problem of inferring images…

Computer Vision and Pattern Recognition · Computer Science 2015-06-23 Miguel Simões , José Bioucas-Dias , Luis B. Almeida , Jocelyn Chanussot

Image registration is an ill-posed inverse problem which often requires regularisation on the solution space. In contrast to most of the current approaches which impose explicit regularisation terms such as smoothness, in this paper we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-09 Chen Qin , Shuo Wang , Chen Chen , Huaqi Qiu , Wenjia Bai , Daniel Rueckert

Registration of pre-operative and follow-up brain MRI scans is challenging due to the large variation of tissue appearance and missing correspondences in tumour recurrence regions caused by tumour mass effect. Although recent deep…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Tony C. W. Mok , Albert C. S. Chung

Intraoperative registration of real-time ultrasound (iUS) to preoperative Magnetic Resonance Imaging (MRI) remains an unsolved problem due to severe modality-specific differences in appearance, resolution, and field-of-view. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Daniil Morozov , Reuben Dorent , Nazim Haouchine

We propose a semantic similarity metric for image registration. Existing metrics like euclidean distance or normalized cross-correlation focus on aligning intensity values, giving difficulties with low intensity contrast or noise. Our…

Computer Vision and Pattern Recognition · Computer Science 2020-11-12 Steffen Czolbe , Oswin Krause , Aasa Feragen

Historical Ca II K spectroheliograms (SHG) are unique in representing long-term variations of the solar chromospheric magnetic field. They usually suffer from numerous problems and lack photometric calibration. Thus accurate processing of…

Solar and Stellar Astrophysics · Physics 2018-01-24 Theodosios Chatzistergos , Ilaria Ermolli , Sami K. Solanki , Natalie A. Krivova