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Ultrasound is a widely accessible and cost-effective medical imaging tool commonly used for prenatal evaluation of the fetal brain. However, it has limitations, particularly in the third trimester, where the complexity of the fetal brain…
Background and Objectives: Cardiovascular magnetic resonance (CMR) imaging is a powerful modality in functional and anatomical assessment for various cardiovascular diseases. Sufficient image quality is essential to achieve proper diagnosis…
Most advanced unsupervised anomaly detection (UAD) methods rely on modeling feature representations of frozen encoder networks pre-trained on large-scale datasets, e.g. ImageNet. However, the features extracted from the encoders that are…
Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to…
Anomaly detection in multivariate time series (MTS) is hindered by dynamic inter-variable dependencies and feature entanglement under spectral noise, and in practice, is further complicated by the absence of anomaly labels. Existing…
The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…
Prototype-based reconstruction methods for unsupervised anomaly detection utilize a limited set of learnable prototypes which only aggregates insufficient normal information, resulting in undesirable reconstruction. However, increasing the…
In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…
The widespread availability of publicly accessible medical images has significantly propelled advancements in various research and clinical fields. Nonetheless, concerns regarding unauthorized training of AI systems for commercial purposes…
High-sensitivity clutter filtering is a fundamental step in ultrasound microvascular imaging. Singular value decomposition (SVD) and robust principal component analysis (rPCA) are the main clutter filtering strategies. However, both…
Ultrasound imaging is challenging to interpret due to non-uniform intensities, low contrast, and inherent artifacts, necessitating extensive training for non-specialists. Advanced representation with clear tissue structure separation could…
Current state-of-the-art multi-class unsupervised anomaly detection (MUAD) methods rely on training encoder-decoder models to reconstruct anomaly-free features. We first show these approaches have an inherent fidelity-stability dilemma in…
Magnetic Resonance Imaging (MRI) offers unparalleled soft-tissue contrast but is fundamentally limited by long acquisition times. While deep learning-based accelerated MRI can dramatically shorten scan times, the reconstruction from…
Unsupervised anomaly detection and segmentation methods train a model to learn the training distribution as `normal'. In the testing phase, they identify patterns that deviate from this normal distribution as `anomalies'. To learn the…
To develop a domain-agnostic, semi-supervised anomaly detection framework that integrates deep reinforcement learning (DRL) to address challenges such as large-scale data, overfitting, and class imbalance, focusing on brain MRI volumes.…
Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…
Cine cardiac magnetic resonance imaging (MRI) is widely used for diagnosis of cardiac diseases thanks to its ability to present cardiovascular features in excellent contrast. As compared to computed tomography (CT), MRI, however, requires a…
Many successful methods developed for medical image analysis that are based on machine learning use supervised learning approaches, which often require large datasets annotated by experts to achieve high accuracy. However, medical data…
Magnetic Resonance Imaging (MRI) has become an important technique in the clinic for the visualization, detection, and diagnosis of various diseases. However, one bottleneck limitation of MRI is the relatively slow data acquisition process.…
Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which pathological changes begin many years before the onset of clinical symptoms, making early detection essential for timely intervention. T1-weighted (T1w) Magnetic…