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The therapeutic working alliance is a critical predictor of psychotherapy success. Traditionally, working alliance assessment relies on questionnaires completed by both therapists and patients. In this paper, we present COMPASS, a novel…

Computation and Language · Computer Science 2025-08-12 Baihan Lin , Djallel Bouneffouf , Yulia Landa , Rachel Jespersen , Cheryl Corcoran , Guillermo Cecchi

Timely identification and accurate risk stratification of cardiovascular disease (CVD) remain essential for reducing global mortality. While existing prediction models primarily leverage structured data, unstructured clinical notes contain…

Computation and Language · Computer Science 2025-07-16 Haowei Yang , Ziyu Shen , Junli Shao , Luyao Men , Xinyue Han , Jing Dong

Alzheimer's disease and related dementias(ADRD) affect nearly five million older adults in the United States, yet more than half remain undiagnosed. Speech-based natural language processing(NLP) offers a scalable approach for detecting…

Depression is one of the most prevalent mental health disorders globally. In recent years, multi-modal data, such as speech, video, and transcripts, has been increasingly used to develop AI-assisted depression assessment systems. Large…

Recently, large language models have shown great potential to transform online medical consultation. Despite this, most research targets improving diagnostic accuracy with ample information, often overlooking the inquiry phase. Some studies…

Computation and Language · Computer Science 2025-03-12 Zhaocheng Liu , Quan Tu , Wen Ye , Yu Xiao , Zhishou Zhang , Hengfu Cui , Yalun Zhu , Qiang Ju , Shizheng Li , Jian Xie

Banks receive millions of reports of fraud, scams, and disputed transactions every year, making it challenging to accurately direct customers to the appropriate specialist teams for assistance. The existing manual process driven by humans…

The high prevalence of depression in society has given rise to the need for new digital tools to assist in its early detection. To this end, existing research has mainly focused on detecting depression in the domain of social media, where…

Computation and Language · Computer Science 2022-04-25 Petr Lorenc , Ana-Sabina Uban , Paolo Rosso , Jan Šedivý

Traditional in-person psychological counseling remains primarily niche, often chosen by individuals with psychological issues, while online automated counseling offers a potential solution for those hesitant to seek help due to feelings of…

Depression is a critical concern in global mental health, prompting extensive research into AI-based detection methods. Among various AI technologies, Large Language Models (LLMs) stand out for their versatility in mental healthcare…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-25 Xiangyu Zhang , Hexin Liu , Kaishuai Xu , Qiquan Zhang , Daijiao Liu , Beena Ahmed , Julien Epps

Evaluating large language models (LLMs) has recently emerged as a critical issue for safe and trustworthy application of LLMs in the medical domain. Although a variety of static medical question-answering (QA) benchmarks have been proposed,…

Computation and Language · Computer Science 2025-12-12 Gyutaek Oh , Sangjoon Park , Byung-Hoon Kim

The application of large language models (LLMs) in clinical decision support faces significant challenges of "tunnel vision" and diagnostic hallucinations present in their processing unstructured electronic health records (EHRs). To address…

Artificial Intelligence · Computer Science 2026-04-28 Zhiqi Lv , Duofan Tu , Jun Li , Mingyue Zhao , Heqin Zhu , Wenliang Li , Shaohua Kevin Zhou

Large, publicly available clinical datasets have emerged as a novel resource for understanding disease heterogeneity and to explore personalization of therapy. These datasets are derived from data not originally collected for research…

Machine Learning · Computer Science 2025-08-14 Anish Narain , Ritam Majumdar , Nikita Narayanan , Dominic Marshall , Sonali Parbhoo

Recent progress on large language models (LLMs) has enabled dialogue agents to generate highly naturalistic and plausible text. However, current LLM language generation focuses on responding accurately to questions and requests with a…

Machine Learning · Computer Science 2024-11-11 Joey Hong , Jessica Lin , Anca Dragan , Sergey Levine

Large language model (LLM) agents have evolved to intelligently process information, make decisions, and interact with users or tools. A key capability is the integration of long-term memory capabilities, enabling these agents to draw upon…

Computation and Language · Computer Science 2025-08-04 Rana Salama , Jason Cai , Michelle Yuan , Anna Currey , Monica Sunkara , Yi Zhang , Yassine Benajiba

It may be difficult for some individuals to open up and share their thoughts and feelings in front of a mental health expert. For those who are more at ease with a virtual agent, conversational agents can serve as an intermediate step in…

Computation and Language · Computer Science 2021-11-17 Harsh Sakhrani , Saloni Parekh , Shubham Mahajan

Depressive and anxiety disorders are widespread, necessitating timely identification and management. Recent advances in Large Language Models (LLMs) offer potential solutions, yet high costs and ethical concerns about training data remain…

Computation and Language · Computer Science 2025-01-28 June M. Liu , Mengxia Gao , Sahand Sabour , Zhuang Chen , Minlie Huang , Tatia M. C. Lee

With the acceleration of the pace of work and life, people have to face more and more pressure, which increases the possibility of suffering from depression. However, many patients may fail to get a timely diagnosis due to the serious…

Signal Processing · Electrical Eng. & Systems 2021-06-02 Lang He , Mingyue Niu , Prayag Tiwari , Pekka Marttinen , Rui Su , Jiewei Jiang , Chenguang Guo , Hongyu Wang , Songtao Ding , Zhongmin Wang , Wei Dang , Xiaoying Pan

Recently introduced dialogue systems have demonstrated high usability. However, they still fall short of reflecting real-world conversation scenarios. Current dialogue systems exhibit an inability to replicate the dynamic, continuous,…

Computation and Language · Computer Science 2024-10-04 Jihyoung Jang , Taeyoung Kim , Hyounghun Kim

The application of AI in psychiatric diagnosis faces significant challenges, including the subjective nature of mental health assessments, symptom overlap across disorders, and privacy constraints limiting data availability. To address…

Social and Information Networks · Computer Science 2025-10-14 Mengxi Xiao , Ben Liu , He Li , Jimin Huang , Qianqian Xie , Xiaofen Zong , Mang Ye , Min Peng

Traditional screening practices for anxiety and depression pose an impediment to monitoring and treating these conditions effectively. However, recent advances in NLP and speech modelling allow textual, acoustic, and hand-crafted…

Sound · Computer Science 2023-01-02 Brian Diep , Marija Stanojevic , Jekaterina Novikova