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Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

Computation and Language · Computer Science 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

Mental health resources available via websites and mobile apps provide support such as advice, journaling, and elements from cognitive behavioral therapy. The proliferation of spoken conversational agents, such as Alexa, Siri, and Google…

Human-Computer Interaction · Computer Science 2020-08-11 Juan C. Quiroz , Tristan Bongolan , Kiran Ijaz

We employ a Large Language Model (LLM) to convert unstructured psychological interviews into structured questionnaires spanning various psychiatric and personality domains. The LLM is prompted to answer these questionnaires by impersonating…

Computation and Language · Computer Science 2024-06-12 Gony Rosenman , Lior Wolf , Talma Hendler

Online health resources and large language models (LLMs) are increasingly used as a first point of contact for medical decision-making, yet their reliability in healthcare remains limited by low accuracy, lack of transparency, and…

Artificial Intelligence · Computer Science 2026-04-22 Yujia Liu , Sophia Yu , Hongyue Jin , Jessica Wen , Alexander Qian , Terrence Lee , Mattheus Ramsis , Gi Won Choi , Lianhui Qin , Xin Liu , Edward J. Wang

Patients with diabetes are at increased risk of comorbid depression or anxiety, complicating their management. This study evaluated the performance of large language models (LLMs) in detecting these symptoms from secure patient messages. We…

We study the emergence of agency from scratch by using Large Language Model (LLM)-based agents. In previous studies of LLM-based agents, each agent's characteristics, including personality and memory, have traditionally been predefined. We…

Artificial Intelligence · Computer Science 2024-11-06 Ryosuke Takata , Atsushi Masumori , Takashi Ikegami

The global mental health crisis is looming with a rapid increase in mental disorders, limited resources, and the social stigma of seeking treatment. As the field of artificial intelligence (AI) has witnessed significant advancements in…

Computation and Language · Computer Science 2023-11-27 Neo Christopher Chung , George Dyer , Lennart Brocki

The development of intelligent agents, particularly those powered by language models (LMs), has shown a critical role in various environments that require intelligent and autonomous decision-making. Environments are not passive testing…

Artificial Intelligence · Computer Science 2025-10-21 Antonin Sulc , Thorsten Hellert

Mental health has attracted substantial attention in recent years and LLM can be an effective technology for alleviating this problem owing to its capability in text understanding and dialogue. However, existing research in this domain…

Computation and Language · Computer Science 2024-12-09 Jinpeng Hu , Tengteng Dong , Luo Gang , Hui Ma , Peng Zou , Xiao Sun , Dan Guo , Xun Yang , Meng Wang

Automatic speech recognition (ASR) technology can aid in the detection, monitoring, and assessment of depressive symptoms in individuals. ASR systems have been used as a tool to analyze speech patterns and characteristics that are…

Human-Computer Interaction · Computer Science 2023-08-17 Alice Othmani , Muhammad Muzammel

LLMs promise to overcome limitations of rule-based mental health chatbots through improved natural language capabilities, yet their ability to deliver evidence-based psychological interventions remains largely unverified because evaluations…

Human-Computer Interaction · Computer Science 2025-12-22 Florian Onur Kuhlmeier , Leon Hanschmann , Melina Rabe , Stefan Luettke , Eva-Lotta Brakemeier , Alexander Maedche

Large Language Models (LLMs) have been increasingly adopted for health-related tasks, yet their performance in depression detection remains limited when relying solely on text input. While Retrieval-Augmented Generation (RAG) typically…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-26 Xiangyu Zhang , Hexin Liu , Qiquan Zhang , Beena Ahmed , Julien Epps

Psychological support hotlines provide critical support for individuals experiencing mental health emergencies, yet current assessments largely rely on human operators whose judgments may vary with professional experience and are…

Computation and Language · Computer Science 2026-05-12 Terumi Chiba , Yang Luo , Ziyun Cui , Yongsheng Tong , Chao Zhang

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient…

Computation and Language · Computer Science 2025-01-03 Kaushik Roy , Harshul Surana , Darssan Eswaramoorthi , Yuxin Zi , Vedant Palit , Ritvik Garimella , Amit Sheth

Individuals with Alzheimer's disease (AD) and Alzheimer's disease-related dementia (ADRD) experience memory and thinking changes that impact their ability to use digital daily management tools. For example, adding an event to a digital…

Artificial Intelligence · Computer Science 2026-05-12 Preyash Yadav , Michelle Cohn , Priyanka Koppolu , Hritvik Agarwal , Amey Gohil , Tejas Patil , Sasha Pimento , Alyssa Weakley

Large Language Models (LLMs) have made significant progress in open-ended dialogue, yet their inability to retain and retrieve relevant information from long-term interactions limits their effectiveness in applications requiring sustained…

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

Despite the impressive capabilities of Large Language Models (LLMs), existing Conversational Health Agents (CHAs) remain static and brittle, incapable of adaptive multi-turn reasoning, symptom clarification, or transparent decision-making.…

Computation and Language · Computer Science 2025-07-11 Xinyi Liu , Dachun Sun , Yi R. Fung , Dilek Hakkani-Tür , Tarek Abdelzaher

Automated depression diagnosis aims to analyze multimodal information from interview videos to predict participants' depression scores. Previous studies often lack clear explanations of how these scores were determined, limiting their…

Artificial Intelligence · Computer Science 2026-03-19 Wei Zhang , Juan Chen , En Zhu , Wenhong Cheng , YunPeng Li , Yanbo J. Wang

Agentic memory systems enable large language model (LLM) agents to maintain state across long interactions, supporting long-horizon reasoning and personalization beyond fixed context windows. Despite rapid architectural development, the…

Computation and Language · Computer Science 2026-05-21 Dongming Jiang , Yi Li , Songtao Wei , Jinxin Yang , Ayushi Kishore , Alysa Zhao , Dingyi Kang , Xu Hu , Feng Chen , Qiannan Li , Bingzhe Li
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