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Total knee arthroplasty (TKA) and total hip arthroplasty (THA) improve symptoms in end-stage osteoarthritis, yet long-term objective characterization of perioperative physical activity trajectories remains limited. We conducted a…

Upper extremity motor impairment affects about 80\% of persons after strokes. For stroke rehabilitation, upper limb kinematic assessments have increasingly been used as primary or secondary outcome measures. Studying the upper extremity…

Quantitative Methods · Quantitative Biology 2023-05-18 Khadija F. Zaidi , Michelle Harris-Love

Knowledge of the mechanical properties of the aorta is essential as important concerns regarding the treatment of aortic pathologies, such as atherosclerosis, aneurysms and dissections, are fundamentally mechanobiological. A comprehensive…

Medical Physics · Physics 2019-12-16 Stéphane Avril

In medical applications, deep learning methods are built to automate diagnostic tasks. However, a clinically relevant question that practitioners usually face, is how to predict the future trajectory of a disease (prognosis). Current…

Machine Learning · Computer Science 2021-12-08 Huy Hoang Nguyen , Simo Saarakkala , Matthew B. Blaschko , Aleksei Tiulpin

The objective assessment of gait kinematics is crucial in evaluating human movement, informing clinical decisions, and advancing rehabilitation and assistive technologies. Assessing gait symmetry, in particular, holds significant importance…

Human-Computer Interaction · Computer Science 2024-11-19 Hanieh Moradi , Yas Vaseghi , Arash Abbasi Larki , Akram Shojaei , Mehdi Delrobaei

Knee osteoarthritis (KOA) affects more than 600 million individuals globally and is associated with significant pain, functional impairment, and disability. While personalized multidisciplinary interventions have the potential to slow…

Artificial Intelligence · Computer Science 2025-11-26 Weizhi Liu , Xi Chen , Zekun Jiang , Liang Zhao , Kunyuan Jiang , Ruisi Tang , Li Wang , Mingke You , Hanyu Zhou , Hongyu Chen , Qiankun Xiong , Yong Nie , Kang Li , Jian Li

Disease-modifying management aims to prevent deterioration and progression of the disease, not just relieve symptoms. Unfortunately, the development of necessary therapies is often hampered by the failure to recognize the presymptomatic…

Obstacle crossing is an essential component of human locomotion, particularly for individuals with lower limb amputations who face elevated risks of imbalance and falls. While prior studies have explored this task, they often lack a…

Medical Physics · Physics 2025-09-24 Jingwen Huang , Shucong Yin , Zhaokai Chen , Hanyang Xu , Chenglong Fu

Understanding internal joint loading is critical for diagnosing gait-related diseases such as knee osteoarthritis; however, current methods of measuring joint risk factors are time-consuming, expensive, and restricted to lab settings. In…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Archit Kambhamettu , Samantha Snyder , Maliheh Fakhar , Samuel Audia , Ross Miller , Jae Kun Shim , Aniket Bera

Osteoarthritis (OA) is a pathology that ultimately causes joint destruction. The cartilage is one of the principal affected tissues. Alterations in the lipid mediators and an imbalance in the metabolism of cells that form the cartilage…

Biological Physics · Physics 2013-06-18 Berta Cillero-Pastor , Gert Eijkel , Andras Kiss , Francisco J. Blanco , Ron M. A. Heeren

Imaging features of knee articular cartilage have been shown to be potential imaging biomarkers for knee osteoarthritis. Despite recent methodological advancements in image analysis techniques like image segmentation, registration, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Yongcheng Yao , Weitian Chen

Muscle forces and joint kinematics estimated with musculoskeletal (MSK) modeling techniques offer useful metrics describing movement quality. Model-based computational MSK models can interpret the dynamic interaction between the neural…

Machine Learning · Computer Science 2023-09-13 Yue Shi , Shuhao Ma , Yihui Zhao

Functional data analysis is an important area in modern statistics and has been successfully applied in many fields. Although many scientific studies aim to find causations, a predominant majority of functional data analysis approaches can…

Applications · Statistics 2020-07-13 Rui Miao , Wu Xue , Xiaoke Zhang

This study addresses the critical need for diverse and comprehensive data focused on human arm joint torques while performing activities of daily living (ADL). Previous studies have often overlooked the influence of objects on joint torques…

Robotics · Computer Science 2024-11-26 Christopher Herneth , Junnan Li , Muhammad Hilman Fatoni , Amartya Ganguly , Sami Haddadin

Plain radiography is the most common modality to assess the stage of osteoarthritis. Our aims were to assess the relationship of radiography-based bone density and texture between radiographs with minimal and clinical post-processing, and…

Medical Physics · Physics 2019-02-07 Jukka Hirvasniemi , Jaakko Niinimäki , Jérôme Thevenot , Simo Saarakkala

Knee osteoarthritis (KOA), a common form of arthritis that causes physical disability, has become increasingly prevalent in society. Employing computer-aided techniques to automatically assess the severity and progression of KOA can greatly…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 Wenhua Wu , Kun Hu , Wenxi Yue , Wei Li , Milena Simic , Changyang Li , Wei Xiang , Zhiyong Wang

Progression of hip osteoarthritis (hip OA) leads to pain and disability, likely leading to surgical treatment such as hip arthroplasty at the terminal stage. The severity of hip OA is often classified using the Crowe and Kellgren-Lawrence…

Knee Osteoarthritis (OA) is a debilitating disease affecting over 250 million people worldwide. Currently, radiologists grade the severity of OA on an ordinal scale from zero to four using the Kellgren-Lawrence (KL) system. Recent studies…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Niamh Belton , Misgina Tsighe Hagos , Aonghus Lawlor , Kathleen M. Curran

Knee osteoporosis weakens the bone tissue in the knee joint, increasing fracture risk. Early detection through X-ray images enables timely intervention and improved patient outcomes. While some researchers have focused on diagnosing knee…

Image and Video Processing · Electrical Eng. & Systems 2024-12-13 Ayesha Siddiqua , Rakibul Hasan , Anichur Rahman , Abu Saleh Musa Miah

Biomechanics and human movement research often involves measuring multiple kinematic or kinetic variables regularly throughout a movement, yielding data that present as smooth, multivariate, time-varying curves and are naturally amenable to…