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We initiate an algebraic approach to study DNA origami structures by associating an element from a monoid to each structure. We identify two types of basic building blocks and describe an DNA origami structure with their composition. These…

Rings and Algebras · Mathematics 2019-01-29 James Garrett , Nataša Jonoska , Hwee Kim , Masahico Saito

This paper describes the model for DNA in MATLAB taking into account all of component atoms. In this model, it is possible to generate sequences with length 10000 basis pairs available for introducing all types of sequences. Once the…

Medical Physics · Physics 2019-05-14 Alexandra Pinto Castellanos

Tile assembly systems in the abstract Tile Assembly Model (aTAM) are computationally universal and capable of building complex shapes, but DNA-based implementations encounter formidable error rates that stifle this theoretical potential.…

Computational Geometry · Computer Science 2024-05-13 Phillip Drake , Daniel Hader , Matthew J. Patitz

In the current world due to the huge demand for storage, DNA-based storage solution sounds quite promising because of their longevity, low power consumption, and high capacity. However in real life storing data in the form of DNA is quite…

Information Theory · Computer Science 2024-04-09 Sanket Doshi , Mihir Gohel , Manish K. Gupta

The flexibility and stiffness of small DNA play a fundamental role ranging from several biophysical processes to nano-technological applications. Here, we estimate the mechanical properties of short double-stranded DNA (dsDNA) having length…

Soft Condensed Matter · Physics 2021-07-09 Supriyo Naskar , Prabal K. Maiti

DNA nanostructures are made using synthetic DNA strands, the sequences of which are designed such that they will self-assemble into the desired form by hybridization of complementary domains. Various structures and devices have been…

Biological Physics · Physics 2015-06-02 Katherine E. Dunn

The Kinetoplast DNA (kDNA) is a two-dimensional Olympic-ring-like network of mutually linked 2.5 kb-long DNA minicircles found in certain parasites called Trypanosomes. Understanding the self-assembly and replication of this structure are…

Soft Condensed Matter · Physics 2022-09-07 Pinyao He , Allard J. Katan , Luca Tubiana , Cees Dekker , Davide Michieletto

We present a theoretical discussion of a self-assembly scheme which makes it possible to use DNA to uniquely encode the composition and structure of micro- and nanoparticle clusters. These anisotropic DNA-decorated clusters can be further…

Soft Condensed Matter · Physics 2009-11-11 Nicholas A. Licata , Alexei V. Tkachenko

In this study, deoxyribonucleic acid (DNA) from bananas was extracted and functionalized and used for the first time as a homeotropic alignment layer for liquid crystals (LCs). Our research was aimed at extracting and investigating DNA from…

Soft Condensed Matter · Physics 2025-04-15 Rafał Węgłowski , Anna Spadło , Dorota Węgłowska

One-dimensional slender bodies can be deformed or shaped into spatially complex curves relatively easily due to their inherent compliance. However, traditional methods of fabricating complex spatial shapes are cumbersome, prone to error…

Applied Physics · Physics 2019-01-30 Soroush Kamrava , Ranajay Ghosh , Yu Yang , Ashkan Vaziri

Self-assembly is a process found everywhere in the Nature. In particular, it is known that DNA self-assembly is Turing universal. Thus one can do arbitrary computations or build nano-structures using DNA self-assembly. In order to…

Emerging Technologies · Computer Science 2016-07-14 Dixita Limbachiya , Dhaval Trivedi , Manish K Gupta

Branched junction molecule assembly of DNA nanostructures, pioneered by Seeman's laboratory in the 1980s, has become increasingly sophisticated, as have the assembly targets. A critical design step is finding minimal sets of branched…

Combinatorics · Mathematics 2021-08-03 Leyda Almodóvar , Jo Ellis-Monaghan , Amanda Harsy , Cory Johnson , Jessica Sorrells

Attaching enzymes to nanostructures has proven useful to the study of enzyme functionality under controlled conditions and has led to new technologies. Often, the utility and interest of enzyme-tethered nanostructures lie in how the…

In component shape optimization, the component properties are often evaluated by computationally expensive simulations. Such optimization becomes unfeasible when it is focused on a global search requiring thousands of simulations to be…

Computational Engineering, Finance, and Science · Computer Science 2025-12-08 Lucie Kubíčková , Onřej Gebouský , Jan Haidl , Martin Isoz

We present a new method for calculating internal forces in DNA structures using coarse-grained models and demonstrate its utility with the oxDNA model. The instantaneous forces on individual nucleotides are explored and related to model…

Soft Condensed Matter · Physics 2021-03-10 Megan C. Engel , Flavio Romano , Ard A. Louis , Jonathan P. K. Doye

Soft robots employing compliant materials and deformable structures offer great potential for wearable devices that are comfortable and safe for human interaction. However, achieving both structural integrity and compliance for comfort…

Robotics · Computer Science 2025-11-04 Sehui Jeong , Magaly C. Aviles , Athena X. Naylor , Cynthia Sung , Allison M. Okamura

Molecular electronics and other technologies whose components comprise individual molecules have been pursued for half a century because the molecular scale represents the limit of miniaturisation of objects whose structure is tuneable for…

In biological cells, DNA replication is carried out by the replisome, a protein complex encompassing multiple DNA polymerases. DNA replication is semi-discontinuous: a DNA polymerase synthesizes one (leading) strand of the DNA continuously,…

Biological Physics · Physics 2025-11-11 Janani G , Deepak Bhat

The study of DNA charge dynamics is a highly interdisciplinary field that bridges physics, chemistry, biology, and medicine, and plays a critical role in processes such as DNA damage detection, protein-DNA interactions, and DNA-based…

Biomolecules · Quantitative Biology 2025-02-12 Dennis Herb , Marco Trenti , Marilena Mantela , Constantinos Simserides , Joachim Ankerhold , Mirko Rossini

Several studies suggest strong correlation between different types of cancer and the relative concentration of short circulating RNA sequences (miRNA). Because of short length and low concentration, miRNA detection is not easy. Standard…

Mesoscale and Nanoscale Physics · Physics 2021-10-25 Luyan Yang , Christophe Cullin , Juan Elezgaray
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