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We introduce $\textit{scadnano}$ (https://scadnano.org) (short for "scriptable cadnano"), a computational tool for designing synthetic DNA structures. Its design is based heavily on cadnano, the most widely-used software for designing DNA…

Emerging Technologies · Computer Science 2020-07-20 David Doty , Benjamin L Lee , Tristan Stérin

Coordinating functional parts to operate in concert is essential for machinery. In gear trains, meshed gears are compactly interlocked, working together to impose rotation or translation. In photosynthetic systems, a variety of biological…

Biological Physics · Physics 2021-05-10 Pengfei Zhan , Maximilian J. Urban , Steffen Both , Xiaoyang Duan , Anton Kuzyk , Thomas Weiss , Na Liu

We present a new, nucleotide-level model for RNA, oxRNA, based on the coarse-graining methodology recently developed for the oxDNA model of DNA. The model is designed to reproduce structural, mechanical and thermodynamic properties of RNA,…

Biological Physics · Physics 2014-06-18 Petr Šulc , Flavio Romano , Thomas E. Ouldridge , Jonathan P. K. Doye , Ard A. Louis

Switchable elements are key components of dynamic technological and biological systems, enabling reversible transitions between well-defined states. Here, we present a DNA origami-based, mechanically bistable snap-through mechanism that can…

To study the elastic properties of rod-like DNA nanostructures, we perform long simulations of these structure using the oxDNA coarse-grained model. By analysing the fluctuations in these trajectories we obtain estimates of the bend and…

Nearly thirty years after its inception, the field of DNA-programmed colloidal self-assembly has begun to realize its initial promise. In this review, we summarize recent developments in designing effective interactions and understanding…

Soft Condensed Matter · Physics 2025-05-08 William M. Jacobs , W. Benjamin Rogers

DNA origami nanostructures provide programmable control over nanoscale geometry but remain challenging to image due to their low atomic number. Here, we systematically evaluate imaging strategies for both stained and unstained DNA origami…

Short, partially complementary, single-stranded (ss)DNA strands can form nanostructures with a wide variety of shapes and mechanical properties. It is well known that semiflexible, linear dsDNA can undergo an isotropic to nematic (IN) phase…

Soft Condensed Matter · Physics 2024-03-07 Kit Gallagher , Jiaming Yu , David A. King , Ren Liu , Erika Eiser

An ideal point light source is as small and as bright as possible. For fluorescent point light sources, homogeneity of the light sources is important as well as that the fluorescent units inside the light source maintain their photophysical…

Chemical Physics · Physics 2019-12-12 Tim Schröder , Max B. Scheible , Florian Steiner , Jan Vogelsang , Philip Tinnefeld

We propose a novel computational framework for modeling and simulating origami structures. In this framework, bilinear solid-shell elements are employed to model the origami panels while crease folding is considered through the angle…

Graphics · Computer Science 2026-01-05 Qixin Liang

We propose an algorithmic framework of a pluripotent structure evolving from a simple compact structure into diverse complex 3-D structures for designing the shape transformable, reconfigurable, and deployable structures and robots. Our…

Computational Engineering, Finance, and Science · Computer Science 2022-08-09 Yu-Ki Lee , Yue Hao , Zhonghua Xi , Woongbae Kim , Youngmin Park , Kyu-Jin Cho , Jyh-Ming Lien , In-Suk Choi

The interaction between light and matter can be controlled efficiently by structuring materials at a length scale shorter than the wavelength of interest. With the goal to build optical devices that operate at the nanoscale, plasmonics has…

Optics · Physics 2021-05-06 Na Liu , Tim Liedl

DNA monolayers with inherent chirality play a pivotal role across various domains, including biosensors, DNA chips, and bioelectronics. Nonetheless, conventional DNA chiral monolayers, typically constructed from single-stranded DNA (ssDNA)…

Membrane morphology and its dynamic adaptation regulate many cellular functions, which are often mediated by membrane proteins. Advances in DNA nanotechnology have enabled the realization of various protein-inspired structures and functions…

One of the frontiers of nanotechnology is advancing beyond the periodic self-assembly of materials. Icosahedral quasicrystals, aperiodic in all directions, represent one of the most challenging targets that have yet to be experimentally…

Soft Condensed Matter · Physics 2024-07-30 Diogo E. P. Pinto , Petr Šulc , Francesco Sciortino , John Russo

Surface plasmon resonances generated in metallic nanostructures can be utilized to tailor electromagnetic fields. The precise spatial arrangement of such structures can result in surprising optical properties that are not found in any…

Nucleic acids, like DNA and RNA, are molecules that are present in any life form. Their most notable function is to encode biological information. Why then would a physicist be interested in these molecules? As we will see, DNA is an…

Biological Physics · Physics 2013-11-12 Alireza Mashaghi , Allard Katan

Origami, the ancient art of folding thin sheets, has attracted increasing attention for its practical value in diverse fields: architectural design, therapeutics, deployable space structures, medical stent design, antenna design and…

Soft Condensed Matter · Physics 2021-06-09 Huan Liu , Paul Plucinsky , Fan Feng , Richard D. James

Shape-morphing finds widespread utility, from the deployment of small stents and large solar sails to actuation and propulsion in soft robotics. Origami structures provide a template for shape-morphing, but rules for designing and folding…

Soft Condensed Matter · Physics 2021-10-25 Xiangxin Dang , Fan Feng , Paul Plucinsky , Richard D. James , Huiling Duan , Jianxiang Wang

The design space for a self-assembled multicomponent objects ranges from a solution in which every building block is unique to one with the minimum number of distinct building blocks that unambiguously define the target structure. Using a…

Soft Condensed Matter · Physics 2023-03-13 Joakim Bohlin , Andrew J. Turberfield , Ard A. Louis , Petr Šulc