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Protein language models (PLMs) learn contextual representations from protein sequences and are profoundly impacting various scientific disciplines spanning protein design, drug discovery, and structural predictions. One particular research…

Quantitative Methods · Quantitative Biology 2024-02-07 Andreas Dounas , Tudor-Stefan Cotet , Alexander Yermanos

Natural language processing (NLP) aims at investigating the interactions between agents and humans, processing and analyzing large amounts of natural language data. Large-scale language models play an important role in current natural…

Artificial Intelligence · Computer Science 2023-04-14 Kebing Jin , Hankz Hankui Zhuo

This paper shows how one can directly apply natural language processing (NLP) methods to classification problems in cheminformatics. Connection between these seemingly separate fields is shown by considering standard textual representation…

Computation and Language · Computer Science 2018-03-09 Stanisław Jastrzębski , Damian Leśniak , Wojciech Marian Czarnecki

Cardiovascular diseases are becoming increasingly prevalent in modern society, with a profound impact on global health and well-being. These Cardiovascular disorders are complex and multifactorial, influenced by genetic predispositions,…

Computation and Language · Computer Science 2025-10-23 Kailai Yang , Yan Leng , Xin Zhang , Tianlin Zhang , Paul Thompson , Bernard Keavney , Maciej Tomaszewski , Sophia Ananiadou

Prediction of protein-ligand interactions (PLI) plays a crucial role in drug discovery as it guides the identification and optimization of molecules that effectively bind to target proteins. Despite remarkable advances in deep…

Biomolecules · Quantitative Biology 2023-07-18 Seokhyun Moon , Sang-Yeon Hwang , Jaechang Lim , Woo Youn Kim

Large Language Models (LLMs) stand at the forefront of a number of Natural Language Processing (NLP) tasks. Despite the widespread adoption of LLMs in NLP, much of their potential in broader fields remains largely unexplored, and…

Machine Learning · Computer Science 2024-03-11 Zhiqiang Zhong , Kuangyu Zhou , Davide Mottin

Recent work in natural language processing (NLP) has yielded appealing results from scaling model parameters and training data; however, using only scale to improve performance means that resource consumption also grows. Such resources…

Objective: This review aims to analyze the application of natural language processing (NLP) techniques in cancer research using electronic health records (EHRs) and clinical notes. This review addresses gaps in the existing literature by…

Computation and Language · Computer Science 2025-02-05 Muhammad Bilal , Ameer Hamza , Nadia Malik

Background:Typically, proteins perform key biological functions by interacting with each other. As a consequence, predicting which protein pairs interact is a fundamental problem. Experimental methods are slow, expensive, and may be error…

Biomolecules · Quantitative Biology 2022-02-08 Leonardo Martini , Adriano Fazzone , Luca Becchetti

Significant advancements have been made in one of the most critical branches of artificial intelligence: natural language processing (NLP). These advancements are exemplified by the remarkable success of OpenAI's GPT-3.5/4 and the recent…

Materials Science · Physics 2025-04-22 Zongrui Pei , Junqi Yin , Jiaxin Zhang

Natural language is one of the most fundamental features that distinguish people from other living things and enable people to communicate each other. Language is a tool that enables people to express their feelings and thoughts and to…

Computation and Language · Computer Science 2019-05-15 Baris Baburoglu , Adem Tekerek , Mehmet Tekerek

In the NLP community, recent years have seen a surge of research activities that address machines' ability to perform deep language understanding which goes beyond what is explicitly stated in text, rather relying on reasoning and knowledge…

Computation and Language · Computer Science 2020-02-27 Shane Storks , Qiaozi Gao , Joyce Y. Chai

Signed languages are the primary means of communication for many deaf and hard of hearing individuals. Since signed languages exhibit all the fundamental linguistic properties of natural language, we believe that tools and theories of…

Computation and Language · Computer Science 2021-07-26 Kayo Yin , Amit Moryossef , Julie Hochgesang , Yoav Goldberg , Malihe Alikhani

Interactive Natural Language Processing (iNLP) has emerged as a novel paradigm within the field of NLP, aimed at addressing limitations in existing frameworks while aligning with the ultimate goals of artificial intelligence. This paradigm…

Proteins are fundamental biological entities that play a key role in life activities. The amino acid sequences of proteins can be folded into stable 3D structures in the real physicochemical world, forming a special kind of…

Machine Learning · Computer Science 2023-01-04 Lirong Wu , Yufei Huang , Haitao Lin , Stan Z. Li

With the growing capabilities of large language models (LLMs), they are increasingly applied in areas like intelligent customer service, code generation, and knowledge management. Natural language (NL) prompts act as the ``APIs'' for…

Software Engineering · Computer Science 2025-08-12 Zhenchang Xing , Yang Liu , Zhuo Cheng , Qing Huang , Dehai Zhao , Daniel Sun , Chenhua Liu

The exponential increase in scientific literature and online information necessitates efficient methods for extracting knowledge from textual data. Natural language processing (NLP) plays a crucial role in addressing this challenge,…

Computation and Language · Computer Science 2025-10-22 Zhyar Rzgar K. Rostam , Gábor Kertész

Protein-specific large language models (Protein LLMs) are revolutionizing protein science by enabling more efficient protein structure prediction, function annotation, and design. While existing surveys focus on specific aspects or…

Protein sequences are abundant in repeating segments, both as exact copies and as approximate segments with mutations. These repeats are important for protein structure and function, motivating decades of algorithmic work on repeat…

Machine Learning · Computer Science 2026-05-26 Gal Pomerants , Yaniv Nikankin , Anja Reusch , Tomer Tsaban , Ora Schueler-Furman , Yonatan Belinkov

Multi-task learning (MTL) has become increasingly popular in natural language processing (NLP) because it improves the performance of related tasks by exploiting their commonalities and differences. Nevertheless, it is still not understood…

Computation and Language · Computer Science 2023-02-16 Zhihan Zhang , Wenhao Yu , Mengxia Yu , Zhichun Guo , Meng Jiang