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A plasmodium of Physarum polycephalum is a very large cell visible by unaided eye. The plasmodium is capable for distributed sensing, parallel information processing, and decentralized optimization. It is an ideal substrate for future and…
Optimization of fluid transport in the slime mold Physarum polycephalum has been the subject of several modeling efforts in recent literature. Existing models assume that the tube adaptation mechanism in P. polycephalum's tubular network is…
Contact inhibition plays a crucial role in the motility of cells, the process of wound healing, and the formation of tumors. By mimicking the mechanical motion of calls crawling on a substrate using a pseudopod, we constructed a minimal…
Network-forming organisms, like fungi and slime molds, dynamically reorganize their networks during foraging. The resulting re-routing of resource flows within the organism's network can significantly impact local ecosystems. In current…
Active fluid transport is a hallmark of many biological transport networks. While animal circulatory systems generally rely on a single heart to drive flows, other organisms employ decentralized local pumps to distribute fluids and…
The plasmodium of the slime mould Physarum polycephalum has recently received significant attention for its value as a highly malleable amorphous computing substrate. In laboratory-based experiments, micro- and nanoscale artificial circuit…
Acellular slime mould Physarum polycephalum is a monstrously large single cell visible by an unaided eye. It shows sophisticated behavioural traits in foraging for nutrients and developing an optimal transport network of protoplasmic tubes…
Plasmodium of \emph{Physarum polycephalum} is a single cell visible by unaided eye. On a non-nutrient substrate the plasmodium propagates as a traveling localization, as a compact wave-fragment of protoplasm. The plasmodium-localization…
A fundamental question in biology is to understand how patterns and shapes emerge from the collective interplay of large numbers of cells. Cells forming two-dimensional epithelial tissues behave as active materials that undergo remodeling…
Very simple organisms, such as the single-celled amoeboid slime mould Physarum polycephalum possess no neural tissue yet, despite this, are known to exhibit complex biological and computational behaviour. Given such limited resources, can…
One of the major characteristics of living organisms is metabolic rate, which is the amount of energy produced per unit of time. When the mass of organisms increases, the metabolic rate also increases (usually as a power function of mass),…
The effects of cell size and deformability on the lateral migration and deformation of living cells flowing through a rectangular microchannel has been numerically investigated and compared with the inertial-microfluidics data on detection…
We consider a partial differential equation model for the growth of heterogeneous cell populations subdivided into multiple distinct discrete phenotypes. In this model, cells preferentially move towards regions where they feel less…
Collective migration dominates many phenomena, from cell movement in living systems to abiotic self-propelling particles. Focusing on the early stages of tumor evolution, we enunciate the principles involved in cell dynamics and highlight…
The slime mould Physarum polycephalum has been used in developing unconventional computing devices for in which the slime mould played a role of a sensing, actuating, and computing device. These devices treated the slime mould rather as an…
Wounding is a severe impairment of function, especially for an exposed organism like the network-forming true slime mould Physarum polycephalum. The tubular network making up the organism's body plan is entirely interconnected and shares a…
In systems as diverse as migrating mammals to road traffic, crowding acts to inhibit efficient collective movement. Bacteria, however, are observed to move in very dense groups containing billions of individuals without causing the gridlock…
Slime mould of Physarum polycephalum is a large cell exhibiting rich spatial non-linear electrical characteristics. We exploit the electrical properties of the slime mould to implement logic gates using a flexible hardware platform designed…
Variations of transport efficiency in structured environments between distinct individuals in actively self-propelled systems is both hard to study and poorly understood. Here, we study the transport of a non-tumbling {\ecoli} strain, an…
One of the essential functions of living organisms is spontaneous migration through the deformation of their body, such as crawling, swimming, and walking. Depending on the size of the object, the efficient migratory mode should be altered…