Related papers: Size-dependent self-avoidance enables superdiffusi…
Groups of cells, including clusters of cancerous cells, multicellular organisms, and developing organs, may both grow and break apart. What physical factors control these fractures? In these processes, what sets the eventual size of…
This paper presents a detailed characterization of the trajectory of a single housefly with free range of a square cage. The trajectory of the fly was recorded and transformed into a time series, which was fully analyzed using an…
Growth patterns generated by filamentous organisms (e.g. actinomycetes and fungi) involve spatial and temporal dynamics at different length scales. Several mathematical models have been proposed in the last thirty years to address these…
Reaction-diffusion equations describe various spatially extended processes that unfold as traveling fronts moving at constant velocity. We introduce and solve analytically a model that, besides such fronts, supports solutions advancing as…
The so-called Filament Based Lamellipodium Model is a complex modeling framework for a very heterogeneous chemo-mechanical system of cell biology. It contains a model for Coulomb repulsion between filaments, whose effect on the stability of…
Gene expression is inherently noisy, posing a challenge to understanding how precise and reproducible patterns of gene expression emerge in mammals. We investigate this phenomenon using gastruloids, an in vitro model for early mammalian…
Scale-free foraging patterns are widespread among animals. These may be the outcome of an optimal searching strategy to find scarce randomly distributed resources, but a less explored alternative is that this behaviour may result from the…
A system far from equilibrium is characterized by unconventional many-body dynamical effects, which can lead to anomalous density fluctuations and mass transport. Interestingly, these structural and dynamic features often emerge…
How do the topology and geometry of a tubular network affect the spread of particles within fluid flows? We investigate patterns of effective dispersion in the hierarchical, biological transport network formed by Physarum polycephalum. We…
Collective migration -- the directed, coordinated motion of many self-propelled agents -- is a fascinating emergent behavior exhibited by active matter that has key functional implications for biological systems. Extensive studies have…
The formation of a collectively moving group benefits individuals within a population in a variety of ways such as ultra-sensitivity to perturbation, collective modes of feeding, and protection from environmental stress. While some…
Recent research has shown that motile cells can adapt their mode of propulsion depending on the environment in which they find themselves. One mode is swimming by blebbing or other shape changes, and in this paper we analyze a class of…
We experimentally derived a unique one-to-one mapping between a range of selected bioactive chemicals and patterns of oscillations of the slime mould's extacellular electrical potential.
How multicellular life forms evolved out from unicellular ones constitutes a major problem in our understanding of the evolution of our biosphere. A recent set of experiments involving yeast cell populations has shown that selection for…
In a prototypical mode of single-cell migration, retrograde cytoskeletal flow is mechanically coupled to the environment, propels the cell, and is sustained by an anterograde cytosolic flow of disassembled cytoskeletal components.…
Subdiffusive motion of tracer particles in complex crowded environments, such as biological cells, has been shown to be widepsread. This deviation from brownian motion is usually characterized by a sublinear time dependence of the mean…
Cell invasion and spatial pattern formation are two distinct manifestations of cellular self-organisation in development, regeneration, and disease. Here, we develop and analyse a unified theoretical framework that links these two seemingly…
We consider the passage of long polymers of length N through a hole in a membrane. If the process is slow, it is in principle possible to focus on the dynamics of the number of monomers s on one side of the membrane, assuming that the two…
Organisms show a remarkable range of sizes, yet the dimensions of a single cell rarely exceed $100$ $\mu$m. While the physical and biological origins of this constraint remain poorly understood, exceptions to this rule give valuable…
A macroscopic theory for describing cellular states during steady-growth is presented, which is based on the consistency between cellular growth and molecular replication, as well as the robustness of phenotypes against perturbations.…