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Background and Objective: Radiomics of knee MRI requires robust, anatomically meaningful regions of interest (ROIs) that jointly capture cartilage and subchondral bone. Most existing work relies on manual ROIs and rarely reports quality…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Tongxu Zhang , Zongpan Li , Aaron Kam Lun Leung , Siu Ngor Fu

Dynamic radiographic measurement of 3D TKA kinematics has provided important information for implant design and surgical technique for over 30 years. However, current methods of measuring TKA kinematics are too cumbersome or time-consuming…

Quantitative Methods · Quantitative Biology 2022-05-03 Andrew Jensen , Paris Flood , Lindsey Palm-Vlasak , Will Burton , Paul Rullkoetter , Scott Banks

T1rho imaging is a promising non-invasive diagnostic tool for early detection of articular cartilage degeneration. A mono-exponential model is normally used to describe the T1rho relaxation process. However, mono-exponentials may not…

The integrity of articular cartilage is a crucial aspect in the early diagnosis of osteoarthritis (OA). Many novel MRI techniques have the potential to assess compositional changes of the cartilage extracellular matrix. Among these…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Alejandra Duarte , Chaitra V. Hegde , Aakash Kaku , Sreyas Mohan , José G. Raya

Osteoporosis is a skeletal disorder that leads to increased fracture risk due to decreased strength of cortical and trabecular bone. Even with state-of-the-art non-invasive assessment methods there is still a high underdiagnosis rate.…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Stefan Reinhold , Timo Damm , Sebastian Büsse , Stanislav N. Gorb , Claus-C. Glüer , Reinhard Koch

Background: MRI is the modality of choice for cartilage imaging; however, its diagnostic performance is variable and significantly lower than the gold standard diagnostic knee arthroscopy. In recent years, deep learning has been used to…

Computer Vision and Pattern Recognition · Computer Science 2021-06-24 Gergo Merkely , Alireza Borjali , Molly Zgoda , Evan M. Farina , Simon Gortz , Orhun Muratoglu , Christian Lattermann , Kartik M. Varadarajan

Vertebrae localization, segmentation and identification in CT images is key to numerous clinical applications. While deep learning strategies have brought to this field significant improvements over recent years, transitional and…

Image and Video Processing · Electrical Eng. & Systems 2022-06-27 Di Meng , Edmond Boyer , Sergi Pujades

Quantitative T1rho mapping has shown promise in clinical and research studies. However, it suffers from long scan times. Deep learning-based techniques have been successfully applied in accelerated quantitative MR parameter mapping.…

Image and Video Processing · Electrical Eng. & Systems 2024-07-25 Yuanyuan Liu , Jinwen Xie , Zhuo-Xu Cui , Qingyong Zhu , Jing Cheng , Dong Liang , Yanjie Zhu

Purpose: To demonstrate the feasibility of performing in vivo imaging and quantitative relaxation mapping of soft and hard tissues using a low-cost, portable MRI scanner, and to establish the methodological foundations for zero echo time…

Aortic shape analysis plays a key role in cardiovascular diagnostics, treatment planning, and understanding disease progression. We present a robust, fully automated pipeline for aortic shape analysis from cardiac MRI, combining deep…

Tissues and Organs · Quantitative Biology 2025-09-15 Nairouz Shehata , Amr Elsawy , Mohamed Nagy , Muhammad ElMahdy , Mariam Ali , Soha Romeih , Heba Aguib , Magdi Yacoub , Ben Glocker

A fully automated knee MRI segmentation method to study osteoarthritis (OA) was developed using a novel hierarchical set of random forests (RF) classifiers to learn the appearance of cartilage regions and their boundaries. A neighborhood…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Satyananda Kashyap , Honghai Zhang , Karan Rao , Milan Sonka

Generating calibrated and sharp neural network predictive distributions for regression problems is essential for optimal decision-making in many real-world applications. To address the miscalibration issue of neural networks, various…

Machine Learning · Computer Science 2024-03-19 Victor Dheur , Souhaib Ben Taieb

The automatic segmentation of human knee cartilage from 3D MR images is a useful yet challenging task due to the thin sheet structure of the cartilage with diffuse boundaries and inhomogeneous intensities. In this paper, we present an…

Computer Vision and Pattern Recognition · Computer Science 2017-11-07 Quan Wang , Dijia Wu , Le Lu , Meizhu Liu , Kim L. Boyer , Shaohua Kevin Zhou

The 3D morphology and quantitative assessment of knee articular cartilages (i.e., femoral, tibial, and patellar cartilage) in magnetic resonance (MR) imaging is of great importance for knee radiographic osteoarthritis (OA) diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Chaowei Tan , Zhennan Yan , Shaoting Zhang , Kang Li , Dimitris N. Metaxas

Background: MR-based subchondral bone effectively predicts knee osteoarthritis. However, its clinical application is limited by the cost and time of MR. Purpose: We aim to develop a novel distillation-learning-based method named SRRD for…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Yuqi Hu , Xiangyu Zhao , Gaowei Qing , Kai Xie , Chenglei Liu , Lichi Zhang

In total hip arthroplasty, analysis of postoperative medical images is important to evaluate surgical outcome. Since Computed Tomography (CT) is most prevalent modality in orthopedic surgery, we aimed at the analysis of CT image. In this…

Image and Video Processing · Electrical Eng. & Systems 2019-06-28 Mitsuki Sakamoto , Yuta Hiasa , Yoshito Otake , Masaki Takao , Yuki Suzuki , Nobuhiko Sugano , Yoshinobu Sato

Image segmentation in total knee arthroplasty is crucial for precise preoperative planning and accurate implant positioning, leading to improved surgical outcomes and patient satisfaction. The biggest challenges of image segmentation in…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Viet Dung Nguyen , Michael T. LaCour , Richard D. Komistek

Knee Osteoarthritis (OA) is a common musculoskeletal disorder in the United States. When diagnosed at early stages, lifestyle interventions such as exercise and weight loss can slow OA progression, but at later stages, only an invasive…

Image and Video Processing · Electrical Eng. & Systems 2020-02-26 Aniket A. Tolpadi , Jinhee J. Lee , Valentina Pedoia , Sharmila Majumdar

Purpose: To develop and evaluate an end-to-end deep learning pipeline for segmentation and analysis of cardiac magnetic resonance images to provide core-lab processing for a multi-centre registry of Fontan patients. Materials and Methods:…

Introduction: Quantitative MRI techniques such as T2 and T1\r{ho} mapping are beneficial in evaluating knee joint pathologies; however, long acquisition times limit their clinical adoption. MIXTURE (Multi-Interleaved X-prepared Turbo-Spin…