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Related papers: Speech as a Biomarker for Disease Detection

200 papers

Alzheimer's Dementia (AD) is an incurable, debilitating, and progressive neurodegenerative condition that affects cognitive function. Early diagnosis is important as therapeutics can delay progression and give those diagnosed vital time.…

Machine Learning · Computer Science 2023-02-28 Thomas Searle , Zina Ibrahim , Richard Dobson

The development of statistical approaches for the joint modelling of the temporal changes of imaging, biochemical, and clinical biomarkers is of paramount importance for improving the understanding of neurodegenerative disorders, and for…

Applications · Statistics 2018-02-16 Marco Lorenzi , Maurizio Filippone , Daniel C. Alexander , Sebastien Ourselin

The growing demand for home healthcare calls for tools that can support care delivery. In this study, we explore automatic health assessment from voice using real-world home care visit data, leveraging the diverse patient information it…

Audio and Speech Processing · Electrical Eng. & Systems 2025-10-22 Yu-Wen Chen , William Ho , Sasha M. Vergez , Grace Flaherty , Pallavi Gupta , Zhihong Zhang , Maryam Zolnoori , Margaret V. McDonald , Maxim Topaz , Zoran Kostic , Julia Hirschberg

Alzheimers disease is a fatal progressive brain disorder that worsens with time. It is high time we have inexpensive and quick clinical diagnostic techniques for early detection and care. In previous studies, various Machine Learning…

Computation and Language · Computer Science 2021-09-27 Akshay Valsaraj , Ithihas Madala , Nikhil Garg , Veeky Baths

This study presents the development and testing of a conversational speech system designed for robots to detect speech biomarkers indicative of cognitive impairments in people living with dementia (PLwD). The system integrates a backend…

Computation and Language · Computer Science 2025-02-18 Rohith Perumandla , Young-Ho Bae , Diego Izaguirre , Esther Hwang , Andrew Murphy , Long-Jing Hsu , Selma Sabanovic , Casey C. Bennett

Alzheimer's disease (AD) is a common form of dementia that severely impacts patient health. As AD impairs the patient's language understanding and expression ability, the speech of AD patients can serve as an indicator of this disease. This…

Audio and Speech Processing · Electrical Eng. & Systems 2023-07-07 Hongmin Cai , Xiaoke Huang , Zhengliang Liu , Wenxiong Liao , Haixing Dai , Zihao Wu , Dajiang Zhu , Hui Ren , Quanzheng Li , Tianming Liu , Xiang Li

Health acoustic sounds such as coughs and breaths are known to contain useful health signals with significant potential for monitoring health and disease, yet are underexplored in the medical machine learning community. The existing deep…

This study investigates whether speech-based depression detection models learn depression-related acoustic biomarkers or instead rely on speaker identity cues. Using the DAIC-WOZ dataset, we propose a data-splitting strategy that controls…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-17 Hsiang-Chen Yeh , Luqi Sun , Aurosweta Mahapatra , Shreeram Suresh Chandra , Emily Mower Provost , Berrak Sisman

Depression is the most common psychological disorder and is considered as a leading cause of disability and suicide worldwide. An automated system capable of detecting signs of depression in human speech can contribute to ensuring timely…

Sound · Computer Science 2023-02-21 Mashrura Tasnim , Jekaterina Novikova

This study introduces Reverse-Speech-Finder (RSF), a groundbreaking neural network backtracking architecture designed to enhance Alzheimer's Disease (AD) diagnosis through speech analysis. Leveraging the power of pre-trained large language…

Machine Learning · Computer Science 2025-05-26 Victor OK Li , Yang Han , Jacqueline CK Lam , Lawrence YL Cheung

Speaker individuality information is among the most critical elements within speech signals. By thoroughly and accurately modeling this information, it can be utilized in various intelligent speech applications, such as speaker recognition,…

Audio and Speech Processing · Electrical Eng. & Systems 2024-11-05 Shuai Wang , Zhengyang Chen , Kong Aik Lee , Yanmin Qian , Haizhou Li

In this study, we executed a genomic analysis with the objective of selecting a set of genes (possibly small) that would help in the detection and classification of samples from patients affected by Parkinson Disease. We performed a…

Machine Learning · Computer Science 2016-02-24 Giancarlo Crocetti , Michael Coakley , Phil Dressner , Wanda Kellum , Tamba Lamin

The use of photoplethysmogram signal (PPG) for heart and sleep monitoring is commonly found nowadays in smartphones and wrist wearables. Besides common usages, it has been proposed and reported that person information can be extracted from…

Audio and Speech Processing · Electrical Eng. & Systems 2019-11-13 Guillermo Cámbara , Jordi Luque , Mireia Farrús

Background: Alzheimer's disease and related dementias (ADRD) are progressive neurodegenerative conditions where early detection is vital for timely intervention and care. Spontaneous speech contains rich acoustic and linguistic markers that…

Computation and Language · Computer Science 2025-06-16 Jingyu Li , Lingchao Mao , Hairong Wang , Zhendong Wang , Xi Mao , Xuelei Sherry Ni

Understanding the relationship between tongue motion patterns during speech and their resulting speech acoustic outcomes -- i.e., articulatory-acoustic relation -- is of great importance in assessing speech quality and developing innovative…

This paper presents a brief survey on Automatic Speech Recognition and discusses the major themes and advances made in the past 60 years of research, so as to provide a technological perspective and an appreciation of the fundamental…

Computation and Language · Computer Science 2010-01-14 M. A. Anusuya , S. K. Katti

We introduce a novel audio processing architecture, the Open Voice Brain Model (OVBM), improving detection accuracy for Alzheimer's (AD) longitudinal discrimination from spontaneous speech. We also outline the OVBM design methodology…

Sound · Computer Science 2021-11-24 Jordi Laguarta Soler , Brian Subirana

Speaker embeddings represent a means to extract representative vectorial representations from a speech signal such that the representation pertains to the speaker identity alone. The embeddings are commonly used to classify and discriminate…

Audio and Speech Processing · Electrical Eng. & Systems 2023-02-07 Adriana Stan

Audio is a rich sensing modality that is useful for a variety of human activity recognition tasks. However, the ubiquitous nature of smartphones and smart speakers with always-on microphones has led to numerous privacy concerns and a lack…

We introduce EmphAssess, a prosodic benchmark designed to evaluate the capability of speech-to-speech models to encode and reproduce prosodic emphasis. We apply this to two tasks: speech resynthesis and speech-to-speech translation. In both…

Computation and Language · Computer Science 2024-10-15 Maureen de Seyssel , Antony D'Avirro , Adina Williams , Emmanuel Dupoux