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Related papers: Speech as a Biomarker for Disease Detection

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Recent years has witnessed an increase in technologies that use speech for the sensing of the health of the talker. This survey paper proposes a general taxonomy of the technologies and a broad overview of current progress and challenges.…

Neurons and Cognition · Quantitative Biology 2024-08-12 Aki Härmä , Bert den Brinker , Ulf Grossekathofer , Okke Ouweltjes , Srikanth Nallanthighal , Sidharth Abrol , Vibhu Sharma

In the past decade, there has been a surge in research examining the use of voice and speech analysis as a means of detecting neurodegenerative diseases such as Alzheimer's. Many studies have shown that certain acoustic features can be used…

Audio and Speech Processing · Electrical Eng. & Systems 2023-07-20 Vrindha M. K. , Geethu V. , Anurenjan P. R. , Deepak S. , Sreeni K. G.

The automatic identification of medication states of Parkinson's disease (PD) patients can assist clinicians in monitoring and scheduling personalized treatments, as well as studying the effects of medication in alleviating the motor…

Parkinson's disease is a progressive neurodegenerative disorder affecting motor and non-motor functions, with speech impairments among its earliest symptoms. Speech impairments offer a valuable diagnostic opportunity, with machine learning…

Machine Learning · Computer Science 2025-04-25 Lorenzo Simone , Mauro Giuseppe Camporeale , Vito Marco Rubino , Vincenzo Gervasi , Giovanni Dimauro

Using speech samples as a biomarker is a promising avenue for detecting and monitoring the progression of Parkinson's disease (PD), but there is considerable disagreement in the literature about how best to collect and analyze such data.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-24 Peter Plantinga , Briac Cordelle , Dominique Louër , Mirco Ravanelli , Denise Klein

Speech and language biomarkers have the potential to be regular, objective assessments of symptom severity in several health conditions, both in-clinic and remotely using mobile devices. However, the complex nature of speech and often…

Speech is a critical biomarker for Huntington Disease (HD), with changes in speech increasing in severity as the disease progresses. Speech analyses are currently conducted using either transcriptions created manually by trained…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-11 Matthew Perez , Wenyu Jin , Duc Le , Noelle Carlozzi , Praveen Dayalu , Angela Roberts , Emily Mower Provost

Early-stage Parkinson's disease (EarlyPD) detection from speech is clinically meaningful yet underexplored, and published results are hard to compare because studies differ in datasets, languages, tasks, evaluation protocols, and EarlyPD…

Audio and Speech Processing · Electrical Eng. & Systems 2026-05-15 Terry Yi Zhong , Cristian Tejedor-Garcia , Khiet P. Truong , Janna Maas , Louis ten Bosch , Bastiaan R. Bloem

Dementia is a syndrome, generally of a chronic nature characterized by a deterioration in cognitive function, especially in the geriatric population and is severe enough to impact their daily activities. Early diagnosis of dementia is…

Audio and Speech Processing · Electrical Eng. & Systems 2020-07-21 Rupayan Chakraborty , Meghna Pandharipande , Chitralekha Bhat , Sunil Kumar Kopparapu

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor symptoms, including altered voice production in the early stages. Early diagnosis is crucial not only to improve PD patients' quality of life but also to…

Audio and Speech Processing · Electrical Eng. & Systems 2025-01-15 Maksim Siniukov , Ellie Xing , Sanaz Attaripour Isfahani , Mohammad Soleymani

Speech holds promise as a cost-effective and non-invasive biomarker for neurological conditions such as Parkinson's disease (PD). While deep learning systems trained on raw audio can find subtle signals not available from hand-crafted…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-24 Peter Plantinga , Jen-Kai Chen , Roozbeh Sattari , Mirco Ravanelli , Denise Klein

Background:Speech patterns have emerged as potential diagnostic markers for conditions with varying etiologies. Machine learning (ML) presents an opportunity to harness these patterns for accurate disease diagnosis. Objective: This review…

Computation and Language · Computer Science 2025-03-10 Birger Moell , Fredrik Sand Aronsson , Per Östberg , Jonas Beskow

The speech of people with Parkinson's Disease (PD) has been shown to hold important clues about the presence and progression of the disease. We investigate the factors based on which humans experts make judgments of the presence of disease…

Timely and accurate assessment of cognitive impairment remains a major unmet need. Speech biomarkers offer a scalable, non-invasive, cost-effective solution for automated screening. However, the clinical utility of machine learning (ML)…

Speech pauses, alongside content and structure, offer a valuable and non-invasive biomarker for detecting dementia. This work investigates the use of pause-enriched transcripts in transformer-based language models to differentiate the…

Audio and Speech Processing · Electrical Eng. & Systems 2024-08-28 Franziska Braun , Sebastian P. Bayerl , Florian Hönig , Hartmut Lehfeld , Thomas Hillemacher , Tobias Bocklet , Korbinian Riedhammer

The detection of pathologies from speech features is usually defined as a binary classification task with one class representing a specific pathology and the other class representing healthy speech. In this work, we train neural networks,…

Audio and Speech Processing · Electrical Eng. & Systems 2023-08-02 Dominik Wagner , Ilja Baumann , Franziska Braun , Sebastian P. Bayerl , Elmar Nöth , Korbinian Riedhammer , Tobias Bocklet

As the aging of society continues to accelerate, Alzheimer's Disease (AD) has received more and more attention from not only medical but also other fields, such as computer science, over the past decade. Since speech is considered one of…

Robotics · Computer Science 2022-11-17 Yuanchao Li , Catherine Lai , Divesh Lala , Koji Inoue , Tatsuya Kawahara

Speech impairments in Parkinson's disease (PD) provide significant early indicators for diagnosis. While models for speech-based PD detection have shown strong performance, their interpretability remains underexplored. This study…

Sound · Computer Science 2024-11-14 Eleonora Mancini , Francesco Paissan , Paolo Torroni , Mirco Ravanelli , Cem Subakan

Alzheimer's disease (AD) is a neurodegenerative disease that affects nearly 50 million individuals across the globe and is one of the leading causes of deaths globally. It is projected that by 2050, the number of people affected by the…

Machine Learning · Computer Science 2021-10-26 Yash Kumar , Piyush Maheshwari , Shreyansh Joshi , Veeky Baths

Parkinsons disease is the second most prevalent neurodegenerative disorder with over ten million active cases worldwide and one million new diagnoses per year. Detecting and subsequently diagnosing the disease is challenging because of…

Computation and Language · Computer Science 2024-04-09 Jonathan Crawford
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