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Related papers: Speech as a Biomarker for Disease Detection

200 papers

Early detection of Alzheimer's disease from spontaneous speech has emerged as a promising non-invasive screening approach. However, the influence of automatic speech recognition (ASR) quality on downstream clinical language modeling remains…

Quantitative Methods · Quantitative Biology 2026-05-01 Himadri S Samanta

Current approaches to detecting depression and anxiety from speech primarily rely on machine learning techniques that utilize hand-engineered paralinguistic features and related acoustic descriptors derived from time- and frequency-domain…

Machine Learning · Computer Science 2026-05-12 Oleksii Abramenko , Noah D. Stein , Colin Vaz

Detection of subtle deficits in everyday functioning due to cognitive impairment is important for early detection of neurodegenerative diseases, particularly Alzheimer's disease. However, current standards for assessment of everyday…

Audio and Speech Processing · Electrical Eng. & Systems 2023-09-13 Yasunori Yamada , Kaoru Shinkawa , Masatomo Kobayashi , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

In this paper, we propose a multi-label classification framework to detect multiple speaking styles in a speech sample. Unlike previous studies that have primarily focused on identifying a single target style, our framework effectively…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-19 Miseul Kim , Seyun Um , Hyeonjin Cha , Hong-goo Kang

Neurodegeneration characterizes individuals with different dementia subtypes (e.g., individuals with Alzheimer's Disease, Primary Progressive Aphasia, and Parkinson's Disease), leading to progressive decline in cognitive, linguistic, and…

Computation and Language · Computer Science 2022-12-06 Charalambos Themistocleous

Respiratory diseases are among the most common causes of severe illness and death worldwide. Prevention and early diagnosis are essential to limit or even reverse the trend that characterizes the diffusion of such diseases. In this regard,…

Audio and Speech Processing · Electrical Eng. & Systems 2019-07-15 Diego Perna , Andrea Tagarelli

Over half of US adults with Alzheimer disease and related dementias remain undiagnosed, and speech-based screening offers a scalable detection approach. We compared large language model adaptation strategies for dementia detection using the…

Early and accessible detection of Alzheimer's disease (AD) remains a major challenge, as current diagnostic methods often rely on costly and invasive biomarkers. Speech and language analysis has emerged as a promising non-invasive and…

Audio and Speech Processing · Electrical Eng. & Systems 2026-03-06 Franziska Braun , Christopher Witzl , Florian Hönig , Elmar Nöth , Tobias Bocklet , Korbinian Riedhammer

It is widely accepted that information derived from analyzing speech (the acoustic signal) and language production (words and sentences) serves as a useful window into the health of an individual's cognitive ability. In fact, most…

Computation and Language · Computer Science 2019-11-06 Rohit Voleti , Julie M. Liss , Visar Berisha

Parkinson's disease is a neurodegenerative disease that can affect a person's movement, speech, dexterity, and cognition. Clinicians primarily diagnose Parkinson's disease by performing a clinical assessment of symptoms. However,…

Neurons and Cognition · Quantitative Biology 2018-11-16 Patrick Schwab , Walter Karlen

Aphasia is a language disorder that affects the speaking ability of millions of patients. This paper presents a new benchmark for Aphasia speech recognition and detection tasks using state-of-the-art speech recognition techniques with the…

Audio and Speech Processing · Electrical Eng. & Systems 2023-05-24 Jiyang Tang , William Chen , Xuankai Chang , Shinji Watanabe , Brian MacWhinney

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. Early detection of AD is crucial for effective intervention and treatment. In this paper, we propose a novel approach…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-29 Yu Pu , Wei-Qiang Zhang

Dementia diagnosis requires a series of different testing methods, which is complex and time-consuming. Early detection of dementia is crucial as it can prevent further deterioration of the condition. This paper utilizes a speech…

Computation and Language · Computer Science 2023-12-18 Zih-Jyun Lin , Yi-Ju Chen , Po-Chih Kuo , Likai Huang , Chaur-Jong Hu , Cheng-Yu Chen

Parkinson's disease (PD) is a progressive neurodegenerative disorder that impacts motor functions and speech characteristics This study focuses on differentiating individuals with Parkinson's disease from healthy controls through the…

Machine Learning · Computer Science 2025-01-27 Burak Çelik , Ayhan Akbal

Parkinson's Disease (PD) affects over 10 million people globally, with speech impairments often preceding motor symptoms by years, making speech a valuable modality for early, non-invasive detection. While recent deep-learning models…

Sound · Computer Science 2025-08-29 Terry Yi Zhong , Cristian Tejedor-Garcia , Martha Larson , Bastiaan R. Bloem

Advancements in spoken language technologies for neurodegenerative speech disorders are crucial for meeting both clinical and technological needs. This overview paper is vital for advancing the field, as it presents a comprehensive review…

Audio and Speech Processing · Electrical Eng. & Systems 2025-08-08 Shakeel A. Sheikh , Md. Sahidullah , Ina Kodrasi

Using picture description speech for dementia detection has been studied for 30 years. Despite the long history, previous models focus on identifying the differences in speech patterns between healthy subjects and patients with dementia but…

Computation and Language · Computer Science 2023-08-17 Youxiang Zhu , Nana Lin , Xiaohui Liang , John A. Batsis , Robert M. Roth , Brian MacWhinney

Dysarthria is a speech disorder characterized by impaired intelligibility and reduced communicative effectiveness. Automatic dysarthria assessment provides a scalable, cost-effective approach for supporting the diagnosis and treatment of…

Audio and Speech Processing · Electrical Eng. & Systems 2025-11-05 Kaimeng Jia , Minzhu Tu , Zengrui Jin , Siyin Wang , Chao Zhang

There has been a surge of interest in leveraging speech as a marker of health for a wide spectrum of conditions. The underlying premise is that any neurological, mental, or physical deficits that impact speech production can be objectively…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-30 Si-Ioi Ng , Lingfeng Xu , Ingo Siegert , Nicholas Cummins , Nina R. Benway , Julie Liss , Visar Berisha

Speech is known to carry health-related attributes, which has emerged as a novel venue for remote and long-term health monitoring. However, existing models are usually tailored for a specific type of disease, and have been shown to lack…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-11 Yi Zhu , Tiago Falk