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Related papers: Mobility-GCN: a human mobility-based graph convolu…

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Human mobility is crucial to understand the transmission pattern of COVID-19 on spatially embedded geographic networks. This pattern seems unpredictable, and the propagation appears unstoppable, resulting in over 350,000 death tolls in the…

Physics and Society · Physics 2022-01-19 Hengfang Deng , Jianxi Gao , Qi Wang

Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the opioid crisis. The relationship between substance use and mental health has been extensively studied, with one possible relationship being…

Artificial Intelligence · Computer Science 2021-03-30 Usha Lokala , Francois Lamy , Triyasha Ghosh Dastidar , Kaushik Roy , Raminta Daniulaityte , Srinivasan Parthasarathy , Amit Sheth

The United States is experiencing an opioid epidemic, and there were more than 10 million opioid misusers aged 12 or older each year. Identifying patients at high risk of Opioid Use Disorder (OUD) can help to make early clinical…

The United States is currently experiencing an unprecedented opioid crisis, and opioid overdose has become a leading cause of injury and death. Effective opioid addiction recovery calls for not only medical treatments, but also behavioral…

Social and Information Networks · Computer Science 2019-12-04 Zhou Yang , Spencer Bradshaw , Rattikorn Hewett , Fang Jin

Motivation: Opioid use disorder (OUD) often arises after prescription opioid exposure and follows transitions among onset, remission, and relapse. Linked EHR-survey resources such as the All of Us Research Program enable stage-specific risk…

Quantitative Methods · Quantitative Biology 2026-01-23 Mengman Wei , Stanislav Listopad , Qian Peng

Drug synergy arises when the combined impact of two drugs exceeds the sum of their individual effects. While single-drug effects on cell lines are well-documented, the scarcity of data on drug synergy, considering the vast array of…

Quantitative Methods · Quantitative Biology 2024-04-29 Kyriakos Schwarz , Alicia Pliego-Mendieta , Amina Mollaysa , Lara Planas-Paz , Chantal Pauli , Ahmed Allam , Michael Krauthammer

Understanding how urban socio-demographic and environmental factors relate with health is essential for public health and urban planning. However, traditional statistical methods struggle with nonlinear effects, while machine learning…

Machine Learning · Computer Science 2025-08-05 Minwei Zhao , Sanja Scepanovic , Stephen Law , Ivica Obadic , Cai Wu , Daniele Quercia

Responding to the U.S. opioid crisis requires a holistic approach supported by evidence from linking and analyzing multiple data sources. This paper discusses how 20 available resources can be combined to answer pressing public health…

Econometrics · Economics 2021-02-11 Olga Scrivner , Elizabeth McAvoy , Thuy Nguyen , Tenzin Choeden , Kosali Simon , Katy Börner

Addiction epidemiology has been an active area of mathematical research in recent years. However, the social and mental processes involved in substance use disorders versus contraction of a pathogenic disease have presented challenges to…

Physics and Society · Physics 2022-02-25 Owen Queen , Vincent Jodoin , Leigh B. Pearcy , W. Christopher Strickland

Opioid addiction is a severe public health threat in the U.S, causing massive deaths and many social problems. Accurate relapse prediction is of practical importance for recovering patients since relapse prediction promotes timely relapse…

Social and Information Networks · Computer Science 2018-11-30 Zhou Yang , Long Nguyen , Fang Jin

Opiates are some of the most effective pain relief medications available for patients suffering from cancer and surgery-related pain. Despite the affordability and effectiveness of these medications, access to opiates is highly…

Applications · Statistics 2016-12-05 Kris Sankaran , Suzanne Tamang , Ami Bhatt

Understanding dynamic human mobility changes and spatial interaction patterns at different geographic scales is crucial for assessing the impacts of non-pharmaceutical interventions (such as stay-at-home orders) during the COVID-19…

Social and Information Networks · Computer Science 2020-11-03 Yuhao Kang , Song Gao , Yunlei Liang , Mingxiao Li , Jinmeng Rao , Jake Kruse

Drug combinations are frequently used for the treatment of cancer patients in order to increase efficacy, decrease adverse side effects, or overcome drug resistance. Given the enormous number of drug combinations, it is cost- and…

Molecular Networks · Quantitative Biology 2021-02-18 Peiran Jiang , Shujun Huang , Zhenyuan Fu , Zexuan Sun , Ted M. Lakowski , Pingzhao Hu

Vicodin is the most commonly prescribed pain reliever in the United States. Research indicates that there are two million people who are currently abusing Vicodin, and the majority of those who abuse Vicodin were initially exposed to it via…

Other Quantitative Biology · Quantitative Biology 2013-08-19 Wendy K. Caldwell , Benjamin Freedman , Luke Settles , Michael M. Thomas , Anarina Murillo , Erika Camacho , Stephen Wirkus

The opioid epidemic continues to ravage communities worldwide, straining healthcare systems, disrupting families, and demanding urgent computational solutions. To combat this lethal opioid crisis, graph learning methods have emerged as a…

Machine Learning · Computer Science 2026-02-17 Tianyi Ma , Yiyang Li , Yiyue Qian , Zheyuan Zhang , Zehong Wang , Chuxu Zhang , Yanfang Ye

Ischaemic heart disease (IHD) remains the primary cause of mortality in the US. This study focuses on using spatio-temporal disease mapping models to explore the temporal trends of IHD at the county level from 1999 to 2021. To manage the…

Applications · Statistics 2024-12-10 A. Urdangarin , T. Goicoa , P. Congdon , MD. Ugarte

Introduction: Chronic pain patients are at increased risk of opioid-misuse. Less is known about the unique risk conferred by each pain-management treatment, as treatments are typically implemented together, confounding their independent…

The opioid epidemic began with prescription pain relievers. In 2010 Purdue Pharma reformulated OxyContin to make it more difficult to abuse. OxyContin misuse fell dramatically, and concurrently heroin deaths began to rise. Previous research…

General Economics · Economics 2021-01-28 Shiyu Zhang , Daniel Guth

Drug-induced parkinsonism affects many older adults with dementia, often causing gait disturbances. New advances in vision-based human pose-estimation have opened possibilities for frequent and unobtrusive analysis of gait in residential…

Computer Vision and Pattern Recognition · Computer Science 2021-10-05 Andrea Sabo , Sina Mehdizadeh , Andrea Iaboni , Babak Taati

The opioid epidemic remains a major public health challenge in the United States, requiring a multi-pronged intervention approach to mitigate harms to communities. Given the heterogeneity of the epidemic across the country, it is crucial…

Applications · Statistics 2026-04-13 Abdulrahman A. Ahmed , M. Amin Rahimian , Qiushi Chen , Praveen Kumar