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We describe two recently proposed machine learning approaches for discovering emerging trends in fatal accidental drug overdoses. The Gaussian Process Subset Scan enables early detection of emerging patterns in spatio-temporal data,…

Opioids are an effective analgesic for acute and chronic pain, but also carry a considerable risk of addiction leading to millions of opioid use disorder (OUD) cases and tens of thousands of premature deaths in the United States yearly.…

COVID-19 has had a large scale negative impact on the health of opioid users exacerbating the health of an already vulnerable population. Critical information on the total impact of COVID-19 on opioid users is unknown due to a lack of…

In the last decade, the United States has lost more than 500,000 people from an overdose involving prescription and illicit opioids making it a national public health emergency (USDHHS, 2017). Medical practitioners require robust and timely…

The opioid epidemic is a crisis that has plagued the United States (US) for decades. One central issue is inequitable access to treatment for opioid use disorder (OUD), which puts certain populations at a higher risk of opioid overdose. We…

In recent years, techniques from Topological Data Analysis (TDA) have proven effective at capturing spatial features of multidimensional data. However, applying TDA to spatiotemporal data remains relatively underexplored. In this work, we…

Opioid and substance misuse is rampant in the United States today, with the phenomenon known as the "opioid crisis". The relationship between substance use and mental health has been extensively studied, with one possible relationship…

Drug overdose is a pressing public health concern in the United States, resulting in a significant number of fatalities each year. In this study, we employ the Journey to Crime (JTC) framework borrowed from the field of environmental…

The synthetic control method is an empirical methodology forcausal inference using observational data. By observing thespread of COVID-19 throughout the world, we analyze the dataon the number of deaths and cases in different regions…

Drug overdose deaths, including those due to prescription opioids, represent a critical public health issue in the United States and worldwide. Artificial intelligence (AI) approaches have been developed and deployed to help prescribers…

The United States (US) opioid crisis contributed to 81,806 fatalities in 2022. It has strained hospitals, treatment facilities, and law enforcement agencies due to the enormous resources and procedures needed to respond to the crisis. As a…

Substance Use Disorders (SUDs) involve the misuse of any or several of a wide array of substances, such as alcohol, opioids, marijuana, and methamphetamine. SUDs are characterized by an inability to decrease use despite severe social,…

Overdose related to prescription opioids have reached an epidemic level in the US, creating an unprecedented national crisis. This has been exacerbated partly due to the lack of tools for physicians to help predict the risk of whether a…

The complex unfolding of the US opioid epidemic in the last 20 years has been the subject of a large body of medical and pharmacological research, and it has sparked a multidisciplinary discussion on how to implement interventions and…

According to the features of drug addiction, this paper constructs an SEIR-based SUC model to describe and predict the spread of drug addiction. Predictions are that the number of drug addictions will continue to fluctuate with reduced…

Opioid overdose rates have increased in the United States over the past decade and reflect a major public health crisis. Modeling and prediction of drug and opioid hotspots, where a high percentage of events fall in a small percentage of…

Drug overdose deaths, including from opioids, remain a significant public health threat to the United States (US). To abate the harms of opioid misuse, understanding its prevalence at the local level is crucial for stakeholders in…

The use of illicit drugs has been on the rise in United States. It is very detrimental on society, as fatal overdose is the fourth leading cause of death in the United States, which is about the same as motor vehicle crashes. Of all illicit…

Graph convolutional neural networks (GCNs) have shown tremendous promise in addressing data-intensive challenges in recent years. In particular, some attempts have been made to improve predictions of Susceptible-Infected-Recovered (SIR)…

Drug overdose has become a public health crisis in the United States with devastating consequences. However, most of the drug overdose incidences are the consequence of recitative polysubstance usage over a defined period of time which can…