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Current clinical practice guidelines for managing Coronary Artery Disease (CAD) account for general cardiovascular risk factors. However, they do not present a framework that considers personalized patient-specific characteristics. Using…
Diagnostic investigation has an important role in risk stratification and clinical decision making of patients with suspected and documented Coronary Artery Disease (CAD). However, the majority of existing tools are primarily focused on the…
Reconstructing a 12-lead electrocardiogram (ECG) from a reduced lead set is an ill-posed inverse problem due to anatomical variability. Standard deep learning methods often ignore underlying cardiac pathology losing vital morphology in…
Diabetes foot ulceration (DFU) and amputation are a cause of significant morbidity. The prevention of DFU may be achieved by the identification of patients at risk of DFU and the institution of preventative measures through education and…
Clinical decision requires reasoning in the presence of imperfect data. DTs are a well-known decision support tool, owing to their interpretability, fundamental in safety-critical contexts such as medical diagnosis. However, learning DTs…
Aortic stenosis (AS) is a common heart valve disease that requires accurate and timely diagnosis for appropriate treatment. Most current automatic AS severity detection methods rely on black-box models with a low level of trustworthiness,…
Vessel stenosis is a major risk factor in cardiovascular diseases (CVD). To analyze the degree of vessel stenosis for supporting the treatment management, extraction of coronary artery area from Computed Tomographic Angiography (CTA) is…
Recent advancements in computer vision promise to automate medical image analysis. Rheumatoid arthritis is an autoimmune disease that would profit from computer-based diagnosis, as there are no direct markers known, and doctors have to rely…
Uncertainty estimation aims to evaluate the confidence of a trained deep neural network. However, existing uncertainty estimation approaches rely on low-dimensional distributional assumptions and thus suffer from the high dimensionality of…
Diabetic Retinopathy (DR) affects individuals with long-term diabetes. Without early diagnosis, DR can lead to vision loss. Fundus photography captures the structure of the retina along with abnormalities indicative of the stage of the…
The determination of a coronary stenosis and its severity in current clinical workflow is typically accomplished manually via physician visual assessment (PVA) during invasive coronary angiography. While PVA has shown large inter-rater…
Deep learning has improved automated electrocardiogram (ECG) classification, but limited insight into prediction reliability hinders its use in safety-critical settings. This paper proposes UCTECG-Net, an uncertainty-aware hybrid…
Knee osteoporosis weakens the bone tissue in the knee joint, increasing fracture risk. Early detection through X-ray images enables timely intervention and improved patient outcomes. While some researchers have focused on diagnosing knee…
Neural networks have recently become popular for a wide variety of uses, but have seen limited application in safety-critical domains such as robotics near and around humans. This is because it remains an open challenge to train a neural…
In recent years, machine learning has witnessed extensive adoption across various sectors, yet its application in medical image-based disease detection and diagnosis remains challenging due to distribution shifts in real-world data. In…
Background. Fully automatic analysis of myocardial perfusion MRI datasets enables rapid and objective reporting of stress/rest studies in patients with suspected ischemic heart disease. Developing deep learning techniques that can analyze…
Deep learning models can enable accurate and efficient disease diagnosis, but have thus far been hampered by the data scarcity present in the medical world. Automated diagnosis studies have been constrained by underpowered single-center…
Ultrasound b-mode imaging is a qualitative approach and diagnostic quality strongly depends on operators' training and experience. Quantitative approaches can provide information about tissue properties; therefore, can be used for…
The ultra-wide optical coherence tomography angiography (OCTA) has become an important imaging modality in diabetic retinopathy (DR) diagnosis. However, there are few researches focusing on automatic DR analysis using ultra-wide OCTA. In…
Diabetic Retinopathy (DR) refers to a barrier that takes place in diabetes mellitus damaging the blood vessel network present in the retina. This may endanger the subjects' vision if they have diabetes. It can take some time to perform a DR…