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Related papers: Confocal Raman Microscopy with Adaptive Optics

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The capability of the adaptive optics to correct for the segmentation error is analyzed in terms of the residual wavefront RMS and the power spectral density of the phase. The analytical model and the end-to-end simulation give…

Astrophysics · Physics 2009-11-11 Natalia Yaitskova , Christophe Verinaud

End-to-end optimization, which simultaneously optimizes optics and algorithms, has emerged as a powerful data-driven method for computational imaging system design. This method achieves joint optimization through backpropagation by…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Chi-Jui Ho , Yash Belhe , Steve Rotenberg , Ravi Ramamoorthi , Tzu-Mao Li , Nicholas Antipa

Label-Free Multiphoton Microscopy is a very powerful optical microscopy that can be applied to study samples with no need for exogenous fluorescent probes, keeping the main benefits of a Multiphoton approach, like longer penetration depths…

Ultra-fine-grained image recognition (UFGIR) categorizes objects with extremely small differences between classes, such as distinguishing between cultivars within the same species, as opposed to species-level classification in fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Edwin Arkel Rios , Femiloye Oyerinde , Min-Chun Hu , Bo-Cheng Lai

Recent advancements in large-scale visual-language pre-trained models have led to significant progress in zero-/few-shot anomaly detection within natural image domains. However, the substantial domain divergence between natural and medical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Chaoqin Huang , Aofan Jiang , Jinghao Feng , Ya Zhang , Xinchao Wang , Yanfeng Wang

Deep-tissue optical imaging suffers from the reduction of resolving power due to tissue-induced optical aberrations and multiple scattering noise. Reflection matrix approaches recording the maps of backscattered waves for all the possible…

Large annotated datasets are crucial for the success of deep neural networks, but labeling data can be prohibitively expensive in domains such as medical imaging. This work tackles the subset selection problem: selecting a small set of the…

Machine Learning · Computer Science 2025-09-29 Noga Bar , Raja Giryes

Raman spectroscopy is one of the most extended experimental techniques to investigate thin-layered 2D materials. For a complete understanding and modeling of the Raman spectrum of a novel 2D material, it is often necessary to combine the…

Correlated rotational alignment spectroscopy correlates observables of ultrafast gas-phase spectroscopy with high-resolution, broad-band rotational Raman spectra. This article reviews the measurement principle of CRASY, existing…

Chemical Physics · Physics 2024-03-07 Thomas Schultz

In optical imaging, light propagation is affected by the inhomogeneities of the medium. Sample-induced aberrations and multiple scattering can strongly degrade the image resolution and contrast. Based on a dynamic correction of the incident…

Imaging through opaque, highly scattering walls is a long sought after capability with potential applications in a variety of fields. The use of wavefront shaping to compensate for scattering has brought a renewed interest as a potential…

Fiber-based micro-endoscopes are a critically important tool for minimally-invasive deep-tissue imaging. However, the state-of-the-art micro-endoscopes cannot perform three-dimensional imaging through dynamically-bent fibers without the use…

Optics · Physics 2022-11-09 Noam Badt , Ori Katz

Label-free optical absorption microscopy techniques continue to evolve as promising tools for label-free histopathological imaging of cells and tissues. However, critical challenges relating to specificity and contrast, as compared to…

Fundus image classification is crucial in the computer aided diagnosis tasks, but label noise significantly impairs the performance of deep neural networks. To address this challenge, we propose a robust framework, Self-Supervised…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Mengwen Ye , Yingzi Huangfu , You Li , Zekuan Yu

Light scattering and aberrations limit optical microscopy in biological tissue, which motivates the development of adaptive optics techniques. Here, we develop a method for adaptive optics with reflected light and deep neural networks…

Optics · Physics 2020-07-28 Ivan Vishniakou , Johannes D. Seelig

Confocal and multiphoton microscopy are effective techniques to obtain high-contrast images of 2-D sections within bulk tissue. However, scattering limits their application to depths only up to ~1 millimeter. Multimode fibers make excellent…

Optics · Physics 2022-02-23 Sakshi Singh , Simon Labouesse , Rafael Piestun

Nonlinear, i.e., multi-photon microscopy is a powerful technique for imaging deep into biological tissues. Its penetration depth can be increased further using adaptive optics. In this work, we present a fast, feedback-based adaptive-optics…

Recently, Visual Foundation Models (VFMs) have shown a remarkable generalization performance in 3D perception tasks. However, their effectiveness in large-scale outdoor datasets remains constrained by the scarcity of accurate supervision…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Pufan Zou , Shijia Zhao , Weijie Huang , Qiming Xia , Chenglu Wen , Wei Li , Cheng Wang

Raman spectroscopy in combination with machine learning has significant promise for applications in clinical settings as a rapid, sensitive, and label-free identification method. These approaches perform well in classifying data that…

Machine Learning · Computer Science 2021-11-12 Yaroslav Balytskyi , Justin Bendesky , Tristan Paul , Guy Hagen , Kelly McNear

We consider the numerical optimization of performance for a computational extension of a confocal microscope. Using a system where the pinhole detector is replaced with a detector array, we seek to exploit this additional information for…

Signal Processing · Electrical Eng. & Systems 2020-12-15 Keith Dillon