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Foundation models (FMs) promise to generalize medical imaging, but their effectiveness varies. It remains unclear how pre-training domain (medical vs. general), paradigm (e.g., text-guided), and architecture influence embedding quality,…

The rapid development of Vision Foundation Models (VFMs), particularly Vision Transformers (ViT) and Segment Anything Model (SAM), has sparked significant advances in the field of medical image analysis. These models have demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2025-02-24 Pengchen Liang , Bin Pu , Haishan Huang , Yiwei Li , Hualiang Wang , Weibo Ma , Qing Chang

Although vision foundation models (VFMs) are increasingly reused for biomedical image analysis, it remains unclear whether the latent representations they provide are general enough to support effective transfer and reuse across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Caterina Fuster-Barceló , Virginie Uhlmann

Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot performance across diverse medical imaging tasks, from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Praveenbalaji Rajendran , Mojtaba Safari , Wenfeng He , Mingzhe Hu , Shansong Wang , Jun Zhou , Xiaofeng Yang

Deformable registration is a fundamental task in medical image processing, aiming to achieve precise alignment by establishing nonlinear correspondences between images. Traditional methods offer good adaptability and interpretability but…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Jing Hu , Kaiwei Yu , Hongjiang Xian , Shu Hu , Xin Wang

Image segmentation is a long-standing challenge in computer vision, studied continuously over several decades, as evidenced by seminal algorithms such as N-Cut, FCN, and MaskFormer. With the advent of foundation models (FMs), contemporary…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Tianfei Zhou , Wang Xia , Fei Zhang , Boyu Chang , Wenguan Wang , Ye Yuan , Ender Konukoglu , Daniel Cremers

Foundation models (FMs) have emerged as a transformative paradigm in medical image analysis, offering the potential to provide generalizable, task-agnostic solutions across a wide range of clinical tasks and imaging modalities. Their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

The deep learning field is converging towards the use of general foundation models that can be easily adapted for diverse tasks. While this paradigm shift has become common practice within the field of natural language processing, progress…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Joana Palés Huix , Adithya Raju Ganeshan , Johan Fredin Haslum , Magnus Söderberg , Christos Matsoukas , Kevin Smith

Medical image segmentation plays an important role in many image-guided clinical approaches. However, existing segmentation algorithms mostly rely on the availability of fully annotated images with pixel-wise annotations for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-04-23 Yuyan Shi , Jialu Ma , Jin Yang , Shasha Wang , Yichi Zhang

Automated segmentation is a fundamental medical image analysis task, which enjoys significant advances due to the advent of deep learning. While foundation models have been useful in natural language processing and some vision tasks for…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Hanxue Gu , Haoyu Dong , Jichen Yang , Maciej A. Mazurowski

Medical image segmentation plays a crucial role in clinical workflows, but domain shift often leads to performance degradation when models are applied to unseen clinical domains. This challenge arises due to variations in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Yingkai Wang , Yaoyao Zhu , Xiuding Cai , Yuhao Xiao , Haotian Wu , Yu Yao

Deep learning underlies most modern approaches and tools in computer vision, including biomedical imaging. However, for interactive semantic segmentation (often called pixel classification in this context) and interactive object-level…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Carolin Teuber , Anwai Archit , Tobias Boothe , Peter Ditte , Jochen Rink , Constantin Pape

Using massive datasets, foundation models are large-scale, pre-trained models that perform a wide range of tasks. These models have shown consistently improved results with the introduction of new methods. It is crucial to analyze how these…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Mobina Mansoori , Sajjad Shahabodini , Farnoush Bayatmakou , Jamshid Abouei , Konstantinos N. Plataniotis , Arash Mohammadi

Domain shift, caused by variations in imaging modalities and acquisition protocols, limits model generalization in medical image segmentation. While foundation models (FMs) trained on diverse large-scale data hold promise for zero-shot…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Soumitri Chattopadhyay , Basar Demir , Marc Niethammer

Large-scale pre-trained models, such as Vision Foundation Models (VFMs), have demonstrated impressive performance across various downstream tasks by transferring generalized knowledge, especially when target data is limited. However, their…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Pengchen Liang , Haishan Huang , Bin Pu , Jianguo Chen , Xiang Hua , Jing Zhang , Weibo Ma , Zhuangzhuang Chen , Yiwei Li , Qing Chang

Foundation models leverage large-scale pretraining to capture extensive knowledge, demonstrating generalization in a wide range of language tasks. By comparison, vision foundation models (VFMs) often exhibit uneven improvements across…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shiqi Huang , Yipei Wang , Natasha Thorley , Alexander Ng , Shaheer Saeed , Mark Emberton , Shonit Punwani , Veeru Kasivisvanathan , Dean Barratt , Daniel Alexander , Yipeng Hu

The deployment of foundation models for medical imaging has demonstrated considerable success. However, their training overheads associated with downstream tasks remain substantial due to the size of the image encoders employed, and the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Chengxi Zeng , Yuxuan Jiang , Fan Zhang , Alberto Gambaruto , Tilo Burghardt

Segmentation of medical images constitutes an essential component of medical image analysis, providing the foundation for precise diagnosis and efficient therapeutic interventions in clinical practices. Despite substantial progress, most…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Muzammal Shafique , Nasir Rahim , Jamil Ahmad , Mohammad Siadat , Khalid Malik , Ghaus Malik

Segmentation is an important analysis task for biomedical images, enabling the study of individual organelles, cells or organs. Deep learning has massively improved segmentation methods, but challenges remain in generalization to new…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Carolin Teuber , Anwai Archit , Constantin Pape

Recently, foundation models have been introduced demonstrating various tasks in the field of computer vision. These models such as Segment Anything Model (SAM) are generalized models trained using huge datasets. Currently, ongoing research…

Computer Vision and Pattern Recognition · Computer Science 2023-06-23 Shurong Chai , Rahul Kumar Jain , Shiyu Teng , Jiaqing Liu , Yinhao Li , Tomoko Tateyama , Yen-wei Chen
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