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The Segment Anything Model (SAM) has garnered significant attention for its versatile segmentation abilities and intuitive prompt-based interface. However, its application in medical imaging presents challenges, requiring either substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Zhiheng Cheng , Qingyue Wei , Hongru Zhu , Yan Wang , Liangqiong Qu , Wei Shao , Yuyin Zhou

Deep learning (DL) has shown remarkable success in various medical imaging data analysis applications. However, it remains challenging for DL models to achieve good generalization, especially when the training and testing datasets are…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Yuemeng Li , Yong Fan

We propose a segmentation framework that uses deep neural networks and introduce two innovations. First, we describe a biophysics-based domain adaptation method. Second, we propose an automatic method to segment white and gray matter, and…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Amir Gholami , Shashank Subramanian , Varun Shenoy , Naveen Himthani , Xiangyu Yue , Sicheng Zhao , Peter Jin , George Biros , Kurt Keutzer

Vision Foundation Models (VFMs) have demonstrated impressive representational capabilities. However, adapting them to downstream tasks via full fine-tuning incurs prohibitive computational and storage overhead. Parameter-Efficient…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Lingyu Xiong , Jinjin Shi , Xuran Xu , Cong Luo , Runyu Shi , Ying Huang

Diffusion models have achieved significant success in both natural image and medical image domains, encompassing a wide range of applications. Previous investigations in medical images have often been constrained to specific anatomical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Yongrui Yu , Yannian Gu , Shaoting Zhang , Xiaofan Zhang

Vision Foundation Models (VFMs) have become a de facto choice for many downstream vision tasks, like image classification, image segmentation, and object localization. However, they can also provide significant utility for downstream 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Johannes Spoecklberger , Wei Lin , Pedro Hermosilla , Sivan Doveh , Horst Possegger , M. Jehanzeb Mirza

Graph foundation models (GFM) aim to acquire transferable knowledge by pre-training on diverse graphs, which can be adapted to various downstream tasks. However, domain shift in graphs is inherently two-dimensional: graphs differ not only…

Computation and Language · Computer Science 2026-03-12 Xingtong Yu , Shenghua Ye , Ruijuan Liang , Chang Zhou , Hong Cheng , Xinming Zhang , Yuan Fang

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

Deep learning has substantially advanced medical image segmentation, yet achieving robust generalization across diverse imaging modalities and anatomical structures remains a major challenge. A key contributor to this limitation lies in how…

Image and Video Processing · Electrical Eng. & Systems 2026-01-23 Shams Nafisa Ali , Taufiq Hasan

Robustness and generalizability in medical image segmentation are often hindered by scarcity and limited diversity of training data, which stands in contrast to the variability encountered during inference. While conventional strategies --…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Yimu Pan , Sitao Zhang , Alison D. Gernand , Jeffery A. Goldstein , James Z. Wang

While foundation models (FMs) offer strong potential for AI-based dementia diagnosis, their integration into federated learning (FL) systems remains underexplored. In this benchmarking study, we systematically evaluate the impact of key…

Graph-structured data pervades domains such as social networks, biological systems, knowledge graphs, and recommender systems. While foundation models have transformed natural language processing, vision, and multimodal learning through…

Vision foundation models (FMs) have become the predominant architecture in computer vision, providing highly transferable representations learned from large-scale, multimodal corpora. Nonetheless, they exhibit persistent limitations on…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Fatemeh Ziaeetabar

Recent advancements in foundation models, typically trained with self-supervised learning on large-scale and diverse datasets, have shown great potential in medical image analysis. However, due to the significant spatial heterogeneity of…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Lingxiao Luo , Xuanzhong Chen , Bingda Tang , Xinsheng Chen , Rong Han , Chengpeng Hu , Yujiang Li , Ting Chen

Foundation models pre-trained on large-scale data have been widely witnessed to achieve success in various natural imaging downstream tasks. Parameter-efficient fine-tuning (PEFT) methods aim to adapt foundation models to new domains by…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Wenqiang Zu , Shenghao Xie , Qing Zhao , Guoqi Li , Lei Ma

Efficient medical image segmentation aims to provide accurate pixel-wise predictions for medical images with a lightweight implementation framework. However, lightweight frameworks generally fail to achieve superior performance and suffer…

Computer Vision and Pattern Recognition · Computer Science 2023-02-21 Xingqun Qi , Zhuojie Wu , Min Ren , Muyi Sun , Caifeng Shan , Zhenan Sun

This work introduces a new framework, ProtoSAM, for one-shot medical image segmentation. It combines the use of prototypical networks, known for few-shot segmentation, with SAM - a natural image foundation model. The method proposed creates…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Lev Ayzenberg , Raja Giryes , Hayit Greenspan

Deep networks are now ubiquitous in large-scale multi-center imaging studies. However, the direct aggregation of images across sites is contraindicated for downstream statistical and deep learning-based image analysis due to inconsistent…

Image and Video Processing · Electrical Eng. & Systems 2021-04-16 Mengwei Ren , Neel Dey , James Fishbaugh , Guido Gerig

Accurate segmentation of organs and lesions in medical images is essential for clinical applications including diagnosis, prognosis, and treatment planning. While Vision Transformers (ViTs) have shown impressive segmentation performance,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Jin Yang , Xiaobing Yu , Peijie Qiu

Foundation segmentation models such as SAM and SAM-2 perform well on natural images but struggle with brain MRIs where structures like the caudate and thalamus lack sharp boundaries and have low contrast. Rather than fine tune these models…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Keith Moore
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