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Related papers: Controllable Synthetic Clinical Note Generation wi…

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This study examines integrating EHRs and NLP with large language models (LLMs) to improve healthcare data management and patient care. It focuses on using advanced models to create secure, HIPAA-compliant synthetic patient notes for…

Computation and Language · Computer Science 2025-06-03 Yao-Shun Chuang , Atiquer Rahman Sarkar , Yu-Chun Hsu , Noman Mohammed , Xiaoqian Jiang

Large-scale clinical data is invaluable to driving many computational scientific advances today. However, understandable concerns regarding patient privacy hinder the open dissemination of such data and give rise to suboptimal siloed…

Computation and Language · Computer Science 2019-05-23 Oren Melamud , Chaitanya Shivade

Deep learning models have demonstrated superior performance in several application problems, such as image classification and speech processing. However, creating a deep learning model using health record data requires addressing certain…

Machine Learning · Computer Science 2021-12-14 Amirsina Torfi , Edward A. Fox , Chandan K. Reddy

Sharing medical data for machine learning model training purposes is often impossible due to the risk of disclosing identifying information about individual patients. Synthetic data produced by generative artificial intelligence (genAI)…

Machine Learning · Computer Science 2026-02-12 Rustam Zhumagambetov , Niklas Giesa , Sebastian D. Boie , Stefan Haufe

De-identification is the task of detecting protected health information (PHI) in medical text. It is a critical step in sanitizing electronic health records (EHRs) to be shared for research. Automatic de-identification classifierscan…

Computation and Language · Computer Science 2019-06-13 Max Friedrich , Arne Köhn , Gregor Wiedemann , Chris Biemann

This paper takes on the problem of automatically identifying clinically-relevant patterns in medical datasets without compromising patient privacy. To achieve this goal, we treat datasets as a black box for both internal and external users…

Software Engineering · Computer Science 2015-01-26 Nafees Qamar , Yilong Yang , Andras Nadas , Zhiming Liu , Janos Sztipanovits

In the era of big data, there is an increasing need for healthcare providers, communities, and researchers to share data and collaborate to improve health outcomes, generate valuable insights, and advance research. The Health Insurance…

Cryptography and Security · Computer Science 2023-05-23 Kai Zhang , Xiaoqian Jiang

Objective: To enable privacy-preserving learning of high quality generative and discriminative machine learning models from distributed electronic health records. Methods and Results: We describe general and scalable strategy to build…

Cryptography and Security · Computer Science 2018-06-19 Marina Blanton , Ah Reum Kang , Subhadeep Karan , Jaroslaw Zola

Data privacy is a critical challenge in modern medical workflows as the adoption of electronic patient records has grown rapidly. Stringent data protection regulations limit access to clinical records for training and integrating machine…

Patient notes contain a wealth of information of potentially great interest to medical investigators. However, to protect patients' privacy, Protected Health Information (PHI) must be removed from the patient notes before they can be…

Computation and Language · Computer Science 2016-11-01 Ji Young Lee , Franck Dernoncourt , Ozlem Uzuner , Peter Szolovits

Clinical notes often describe the most important aspects of a patient's physiology and are therefore critical to medical research. However, these notes are typically inaccessible to researchers without prior removal of sensitive protected…

Computation and Language · Computer Science 2018-03-08 Willie Boag , Tristan Naumann , Peter Szolovits

Federated Learning (FL) offers a promising approach for training clinical AI models without centralizing sensitive patient data. However, its real-world adoption is hindered by challenges related to privacy, resource constraints, and…

For sharing privacy-sensitive data, de-identification is commonly regarded as adequate for safeguarding privacy. Synthetic data is also being considered as a privacy-preserving alternative. Recent successes with numerical and tabular data…

Computation and Language · Computer Science 2025-03-05 Atiquer Rahman Sarkar , Yao-Shun Chuang , Noman Mohammed , Xiaoqian Jiang

Training data is fundamental to the success of modern machine learning models, yet in high-stakes domains such as healthcare, the use of real-world training data is severely constrained by concerns over privacy leakage. A promising solution…

Deep learning continues to rapidly evolve and is now demonstrating remarkable potential for numerous medical prediction tasks. However, realizing deep learning models that generalize across healthcare organizations is challenging. This is…

Machine Learning · Computer Science 2023-08-23 Zhuohang Li , Chao Yan , Xinmeng Zhang , Gharib Gharibi , Zhijun Yin , Xiaoqian Jiang , Bradley A. Malin

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

Machine Learning (ML) has achieved enormous success in solving a variety of problems in computer vision, speech recognition, object detection, to name a few. The principal reason for this success is the availability of huge datasets for…

Cryptography and Security · Computer Science 2023-02-14 Efstathia Soufleri , Gobinda Saha , Kaushik Roy

Access to genomic data is highly regulated due to its sensitive nature. While safeguards are essential, cumbersome data access processes pose a significant barrier to the development of AI methods for genomics. Synthetic data generation can…

Cryptography and Security · Computer Science 2026-05-01 Daniil Filienko , Martine De Cock , Sikha Pentyala

Federated learning enables training a global machine learning model from data distributed across multiple sites, without having to move the data. This is particularly relevant in healthcare applications, where data is rife with personal,…

Cryptography and Security · Computer Science 2020-02-24 Olivia Choudhury , Aris Gkoulalas-Divanis , Theodoros Salonidis , Issa Sylla , Yoonyoung Park , Grace Hsu , Amar Das

The generation of privacy-preserving synthetic datasets is a promising avenue for overcoming data scarcity in medical AI research. Post-hoc privacy filtering techniques, designed to remove samples containing personally identifiable…

Machine Learning · Computer Science 2025-10-03 Adil Koeken , Alexander Ziller , Moritz Knolle , Daniel Rueckert
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