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Simulation studies like finite element (FE) modeling provide insight into knee joint mechanics without patient experimentation. Generic FE models represent biomechanical behavior of the tissue by overlooking variations in geometry, loading,…
Scanner drift is a well-known magnetic resonance imaging (MRI) artifact characterized by gradual signal degradation and scan intensity changes over time. In addition, hardware and software updates may imply abrupt changes in signal. The…
In sports analytics, an understanding of accurate on-field 3D knee joint moments (KJM) could provide an early warning system for athlete workload exposure and knee injury risk. Traditionally, this analysis has relied on captive laboratory…
Magnetic resonance imaging (MRI) is a cornerstone of modern medical imaging. However, long image acquisition times, the need for qualitative expert analysis, and the lack of (and difficulty extracting) quantitative indicators that are…
Osteoarthritis (OA) is one of the major health issues among the elderly population. MRI is the most popular technology to observe and evaluate the progress of OA course. However, the extreme labor cost of MRI analysis makes the process…
The latest advances in computer-assisted precision medicine are making it feasible to move from population-wide models that are useful to discover aggregate patterns that hold for group-based analysis to patient-specific models that can…
Bone segmentation from CT images is a task that has been worked on for decades. It is an important ingredient to several diagnostics or treatment planning approaches and relevant to various diseases. As high-quality manual and…
Quantitative MRI is highly desirable in terms of intrinsic tissue parameters such as T1, T2 and proton density. This approach promises to minimize diagnostic variability and differentiate normal and pathological tissues by comparing tissue…
Medical image classification is a critical task in healthcare, enabling accurate and timely diagnosis. However, deploying deep learning models on resource-constrained edge devices presents significant challenges due to computational and…
Body composition assessment using CT images can potentially be used for a number of clinical applications, including the prognostication of cardiovascular outcomes, evaluation of metabolic health, monitoring of disease progression,…
Computational pathology models that use digitized histopathology whole-slide images have the potential to become a cost-effective and scalable alternative to molecular assays for the prediction of genomic biomarkers, a key task in precision…
Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…
Recent advancements in computer vision promise to automate medical image analysis. Rheumatoid arthritis is an autoimmune disease that would profit from computer-based diagnosis, as there are no direct markers known, and doctors have to rely…
Involuntary subject motion is the main source of artifacts in weight-bearing cone-beam CT of the knee. To achieve image quality for clinical diagnosis, the motion needs to be compensated. We propose to use inertial measurement units (IMUs)…
Cardiac Magnetic Resonance Imaging (MRI) plays an important role in the analysis of cardiac function. However, the acquisition is often accompanied by motion artefacts because of the difficulty of breath-hold, especially for acute symptoms…
Spine-related diseases have high morbidity and cause a huge burden of social cost. Spine imaging is an essential tool for noninvasively visualizing and assessing spinal pathology. Segmenting vertebrae in computed tomography (CT) images is…
Robotic-assisted orthopaedic surgeries demand accurate, automated leg manipulation for improved spatial accuracy to reduce iatrogenic damage. In this study, we propose novel rigid body designs and an optical tracking volume setup for…
CT and MRI are two of the most informative modalities in spinal diagnostics and treatment planning. CT is useful when analysing bony structures, while MRI gives information about the soft tissue. Thus, fusing the information of both…
Knee osteoarthritis (KOA) is a prevalent musculoskeletal disorder, often diagnosed using X-rays due to its cost-effectiveness. While Magnetic Resonance Imaging (MRI) provides superior soft tissue visualization and serves as a valuable…
This chapter presents the investigations and the results of feature learning using convolutional neural networks to automatically assess knee osteoarthritis (OA) severity and the associated clinical and diagnostic features of knee OA from…