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A critical task in systems biology is the identification of genes that interact to control cellular processes by transcriptional activation of a set of target genes. Many methods have been developed to use statistical correlations in…

Quantitative Methods · Quantitative Biology 2010-11-24 Adam A. Margolin , Kai Wang , Andrea Califano , Ilya Nemenman

Understanding the process by which a contagion disseminates throughout a network is of great importance in many real world applications. The required sophistication of the inference approach depends on the type of information we want to…

Social and Information Networks · Computer Science 2017-05-26 Shohreh Shaghaghian , Mark Coates

We observe that the human trajectory is not only forward predictable, but also backward predictable. Both forward and backward trajectories follow the same social norms and obey the same physical constraints with the only difference in…

Computer Vision and Pattern Recognition · Computer Science 2020-04-10 Hao Sun , Zhiqun Zhao , Zhihai He

Network reconstruction is the first step towards understanding, diagnosing and controlling the dynamics of complex networked systems. It allows us to infer properties of the interaction matrix, which characterizes how nodes in a system…

Systems and Control · Computer Science 2016-01-12 Marco Tulio Angulo , Jaime A. Moreno , Albert-László Barabási , Yang-Yu Liu

We consider networks of dynamical units that evolve in time according to different laws, and are coupled to each other in highly irregular ways. Studying how to steer the dynamics of such systems towards a desired evolution is of great…

Physics and Society · Physics 2020-12-01 Ricardo Gutiérrez , Massimo Materassi , Stefano Focardi , Stefano Boccaletti

Networks are models representing relationships between entities. Often these relationships are explicitly given, or we must learn a representation which generalizes and predicts observed behavior in underlying individual data (e.g.…

Social and Information Networks · Computer Science 2017-09-19 Ivan Brugere , Chris Kanich , Tanya Y. Berger-Wolf

Many dynamical processes of complex systems can be understood as the dynamics of a group of nodes interacting on a given network structure. However, finding such interaction structure and node dynamics from time series of node behaviours is…

Physics and Society · Physics 2022-06-28 Yan Zhang , Yu Guo , Zhang Zhang , Mengyuan Chen , Shuo Wang , Jiang Zhang

We study the problem of inferring network topology from information cascades, in which the amount of time taken for information to diffuse across an edge in the network follows an unknown distribution. Unlike previous studies, which assume…

Social and Information Networks · Computer Science 2019-03-05 Feng Ji , Wenchang Tang , Wee Peng Tay , Edwin K. P. Chong

Network embedding has recently emerged as a promising technique to embed nodes of a network into low-dimensional vectors. While fairly successful, most existing works focus on the embedding techniques for static networks. But in practice,…

Social and Information Networks · Computer Science 2020-10-28 Zenan Xu , Zijing Ou , Qinliang Su , Jianxing Yu , Xiaojun Quan , Zhenkun Lin

Network structures in various backgrounds play important roles in social, technological, and biological systems. However, the observable network structures in real cases are often incomplete or unavailable due to measurement errors or…

Machine Learning · Computer Science 2020-01-22 Mengyuan Chen , Jiang Zhang , Zhang Zhang , Lun Du , Qiao Hu , Shuo Wang , Jiaqi Zhu

A crucial challenge in network theory is the study of the robustness of a network after facing a sequence of failures. In this work, we propose a dynamical definition of network's robustness based on Information Theory, that considers…

The well-known issue of reconstructing regulatory networks from gene expression measurements has been somewhat disrupted by the emergence and rapid development of single-cell data. Indeed, the traditional way of seeing a gene regulatory…

Molecular Networks · Quantitative Biology 2021-10-01 Ulysse Herbach

Network science has become an essential interdisciplinary tool for understanding complex biological systems. However, because these systems undergo continuous, often stimulus-driven changes in both structure and function, traditional static…

Molecular Networks · Quantitative Biology 2025-05-19 Abir Khazaal , Fatemeh Vafaee

The dynamics of biological systems, from proteins to cells to organisms, is complex and stochastic. To decipher their physical laws, we need to bridge between experimental observations and theoretical modeling. Thanks to progress in…

Soft Condensed Matter · Physics 2024-06-05 Pierre Ronceray

Transcriptomic data is a treasure-trove in modern molecular biology, as it offers a comprehensive viewpoint into the intricate nuances of gene expression dynamics underlying biological systems. This genetic information must be utilised to…

Molecular Networks · Quantitative Biology 2023-12-13 Vikram Singh , Vikram Singh

Systems consisting of interacting agents are prevalent in the world, ranging from dynamical systems in physics to complex biological networks. To build systems which can interact robustly in the real world, it is thus important to be able…

In a complex system, the interactions between individual agents often lead to emergent collective behavior like spontaneous synchronization, swarming, and pattern formation. The topology of the network of interactions can have a dramatic…

Adaptation and Self-Organizing Systems · Physics 2022-07-25 Mark J Panaggio , Maria-Veronica Ciocanel , Lauren Lazarus , Chad M Topaz , Bin Xu

We consider the problem of inferring the functional connectivity of a large-scale computer network from sparse time series of events emitted by its nodes. We do so under the following three domain-specific constraints: (a) non-stationarity…

Machine Learning · Computer Science 2018-02-13 Antoine Messager , George Parisis , Istvan Z Kiss , Robert Harper , Phil Tee , Luc Berthouze

We propose a conceptually novel method of reconstructing the topology of dynamical networks. By examining the correlation between the variable of one node and the derivative of another node, we derive a simple matrix equation yielding the…

Data Analysis, Statistics and Probability · Physics 2015-06-11 Zoran Levnajić

Inferring the network topology from the dynamics is a fundamental problem with wide applications in geology, biology and even counter-terrorism. Based on the propagation process, we present a simple method to uncover the network topology.…

Physics and Society · Physics 2013-11-21 An Zeng