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Motivation: Inferring the structure of gene regulatory networks from high--throughput datasets remains an important and unsolved problem. Current methods are hampered by problems such as noise, low sample size, and incomplete…

Quantitative Methods · Quantitative Biology 2017-12-04 Phan Nguyen , Rosemary Braun

The \emph{Steiner tree} problem is one of the fundamental and classical problems in combinatorial optimization. In this paper, we study this problem in the $\mathcal{CONGESTED}$ $\mathcal{CLIQUE}$ model of distributed computing and present…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-07-31 Parikshit Saikia , Sushanta Karmakar

We give an $m^{1+o(1)}\beta^{o(1)}$-time algorithm for generating a uniformly random spanning tree in an undirected, weighted graph with max-to-min weight ratio $\beta$. We also give an $m^{1+o(1)}\epsilon^{-o(1)}$-time algorithm for…

Data Structures and Algorithms · Computer Science 2017-11-20 Aaron Schild

We give the first O(m polylog(n)) time algorithms for approximating maximum flows in undirected graphs and constructing polylog(n) -quality cut-approximating hierarchical tree decompositions. Our algorithm invokes existing algorithms for…

Data Structures and Algorithms · Computer Science 2015-11-18 Richard Peng

Let $G$ be an $n$-node simple directed planar graph with nonnegative edge weights. We study the fundamental problems of computing (1) a global cut of $G$ with minimum weight and (2) a~cycle of $G$ with minimum weight. The best previously…

Data Structures and Algorithms · Computer Science 2017-03-24 Hung-Chun Liang , Hsueh-I Lu

Phylogenetic (evolutionary) trees and networks are leaf-labeled graphs that are widely used to represent the evolutionary relationships between entities such as species, languages, cancer cells, and viruses. To reconstruct and analyze…

Data Structures and Algorithms · Computer Science 2023-08-21 Michael J. Dinneen , Pankaj S. Ghodla , Simone Linz

In the context of reconstructing phylogenetic networks from a collection of phylogenetic trees, several characterisations and subsequently algorithms have been established to reconstruct a phylogenetic network that collectively embeds all…

Combinatorics · Mathematics 2023-08-21 Janosch Döcker , Simone Linz , Charles Semple

We present the first sublinear-in-$n$ round algorithm for sampling an approximately uniform spanning tree of an $n$-vertex graph in the CongestedClique model of distributed computing. In particular, our algorithm requires…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-12 Sriram V. Pemmaraju , Sourya Roy , Joshua Z. Sobel

Phylogenetic networks are useful in representing the evolutionary history of taxa. In certain scenarios, one requires a way to compare different networks. In practice, this can be rather difficult, except within specific classes of…

Populations and Evolution · Quantitative Biology 2025-07-30 Christopher Reichling , Leo van Iersel , Yukihiro Murakami

In this paper, we study the problem of constructing a network by observing ordered connectivity constraints, which we define herein. These ordered constraints are made to capture realistic properties of real-world problems that are not…

Data Structures and Algorithms · Computer Science 2017-02-24 Yi Huang , Mano Vikash Janardhanan , Lev Reyzin

Let G be a directed graph with n vertices and non-negative weights in its directed edges, embedded on a surface of genus g, and let f be an arbitrary face of G. We describe a randomized algorithm to preprocess the graph in O(gn log n) time…

Data Structures and Algorithms · Computer Science 2013-05-13 Sergio Cabello , Erin Wolf Chambers , Jeff Erickson

Phylogenetic networks are notoriously difficult to reconstruct. Here we suggest that it can be useful to view unknown genetic distance along edges in phylogenetic networks as analogous to unknown resistance in electric circuits. This…

Combinatorics · Mathematics 2020-10-01 Stefan Forcey , Drew Scalzo

Quartet Reconstruction, the task of recovering a phylogenetic tree from smaller trees on four species called \textit{quartets}, is a well-studied problem in theoretical computer science with far-reaching connections to statistics, graph…

Data Structures and Algorithms · Computer Science 2026-04-21 Dionysis Arvanitakis , Vaggos Chatziafratis , Yiyuan Luo , Konstantin Makarychev

Phylogenetic networks are rooted directed acyclic graphs that represent evolutionary relationships between species whose past includes reticulation events such as hybridisation and horizontal gene transfer. To search the space of…

Combinatorics · Mathematics 2019-04-09 Jonathan Klawitter , Simone Linz

Finding dense subgraphs is a fundamental algorithmic tool in data mining, community detection, and clustering. In this problem, one aims to find an induced subgraph whose edge-to-vertex ratio is maximized. We study the directed case of this…

Data Structures and Algorithms · Computer Science 2023-11-21 Slobodan Mitrović , Theodore Pan

We present near-optimal algorithms for detecting small vertex cuts in the CONGEST model of distributed computing. Despite extensive research in this area, our understanding of the vertex connectivity of a graph is still incomplete,…

Data Structures and Algorithms · Computer Science 2023-06-21 Merav Parter , Asaf Petruschka

A distributed network is modeled by a graph having $n$ nodes (processors) and diameter $D$. We study the time complexity of approximating {\em weighted} (undirected) shortest paths on distributed networks with a $O(\log n)$ {\em bandwidth…

Data Structures and Algorithms · Computer Science 2014-05-23 Danupon Nanongkai

We show the existence of an exact mimicking network of $k^{O(\log k)}$ edges for minimum multicuts over a set of terminals in an undirected graph, where $k$ is the total capacity of the terminals, as well as a method for computing a…

Data Structures and Algorithms · Computer Science 2021-03-09 Magnus Wahlström

Phylogenetic networks generalise phylogenetic trees and allow for the accurate representation of the evolutionary history of a set of present-day species whose past includes reticulate events such as hybridisation and lateral gene transfer.…

Populations and Evolution · Quantitative Biology 2018-09-05 Joan Carles Pons , Charles Semple , Mike Steel

The maximum/minimum bisection problems are, given an edge-weighted graph, to find a bipartition of the vertex set into two sets whose sizes differ by at most one, such that the total weight of edges between the two sets is…

Data Structures and Algorithms · Computer Science 2020-09-17 Tesshu Hanaka , Yasuaki Kobayashi , Taiga Sone