English
Related papers

Related papers: Latent Causal Modeling for 3D Brain MRI Counterfac…

200 papers

Deep learning models have revolutionized the field of medical image analysis, offering significant promise for improved diagnostics and patient care. However, their performance can be misleadingly optimistic due to a hidden pitfall called…

Image and Video Processing · Electrical Eng. & Systems 2025-05-12 Dewinda Julianensi Rumala

Diffusion models have shown great promise for image generation, beating GANs in terms of generation diversity, with comparable image quality. However, their application to 3D shapes has been limited to point or voxel representations that…

Computer Vision and Pattern Recognition · Computer Science 2022-12-16 Gimin Nam , Mariem Khlifi , Andrew Rodriguez , Alberto Tono , Linqi Zhou , Paul Guerrero

Purpose. Brain Magnetic Resonance Images (MRIs) are essential for the diagnosis of neurological diseases. Recently, deep learning methods for unsupervised anomaly detection (UAD) have been proposed for the analysis of brain MRI. These…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Marcel Bengs , Finn Behrendt , Julia Krüger , Roland Opfer , Alexander Schlaefer

Clinical decision-making relies heavily on causal reasoning and longitudinal analysis. For example, for a patient with Alzheimer's disease (AD), how will the brain grey matter atrophy in a year if intervened on the A-beta level in…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Yujia Li , Han Li , ans S. Kevin Zhou

The mainstream of data-driven abstractive summarization models tends to explore the correlations rather than the causal relationships. Among such correlations, there can be spurious ones which suffer from the language prior learned from the…

Computation and Language · Computer Science 2023-08-25 Lu Chen , Ruqing Zhang , Wei Huang , Wei Chen , Jiafeng Guo , Xueqi Cheng

Deep generative models have demonstrated remarkable success in medical image synthesis. However, ensuring conditioning faithfulness and high-quality synthetic images for direct or counterfactual generation remains a challenge. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Fangrui Huang , Alan Wang , Binxu Li , Bailey Trang , Ridvan Yesiloglu , Tianyu Hua , Wei Peng , Ehsan Adeli

Counterfactual medical image generation effectively addresses data scarcity and enhances the interpretability of medical images. However, due to the complex and diverse pathological features of medical images and the imbalanced class…

Computer Vision and Pattern Recognition · Computer Science 2025-04-25 Weizhi Nie , Zichun Zhang , Weijie Wang , Bruno Lepri , Anan Liu , Nicu Sebe

Causal structure discovery methods are commonly applied to structured data where the causal variables are known and where statistical testing can be used to assess the causal relationships. By contrast, recovering a causal structure from…

Computation and Language · Computer Science 2024-10-10 Gaël Gendron , Jože M. Rožanec , Michael Witbrock , Gillian Dobbie

In the medical domain, acquiring large datasets is challenging due to both accessibility issues and stringent privacy regulations. Consequently, data availability and privacy protection are major obstacles to applying machine learning in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Wenwu Tang , Khaled Seyam , Bin Yang

Data augmentation is essential for medical research to increase the size of training datasets and achieve better results. In this work, we experiment three GAN architectures with different loss functions to generate new brain MRIs. The…

Image and Video Processing · Electrical Eng. & Systems 2020-02-10 Antoine Delplace

Generative data augmentation with latent diffusion models is a promising strategy for addressing class imbalance in medical imaging, yet current approaches focus on perceptual fidelity and domain-specific autoencoder fine-tuning while…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Mischa Dombrowski , Felix Nützel , Bernhard Kainz

Machine learning in drug discovery has been focused on virtual screening of molecular libraries using discriminative models. Generative models are an entirely different approach that learn to represent and optimize molecules in a continuous…

Quantitative Methods · Quantitative Biology 2020-11-17 Matthew Ragoza , Tomohide Masuda , David Ryan Koes

Despite advances in deep learning, robustness under domain shift remains a major bottleneck in medical imaging settings. Findings on natural images suggest that deep neural models can show a strong textural bias when carrying out image…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Seoin Chai , Daniel Rueckert , Ahmed E. Fetit

Objective. Standard Magnetic Resonance Imaging (MRI) reconstruction pipelines discard phase information captured during acquisition, despite evidence that it encodes tissue properties relevant to tumor diagnosis. Current machine learning…

Image and Video Processing · Electrical Eng. & Systems 2026-04-17 Marco Schlimbach , Moritz Rempe , Jessica Mnischek , Lukas T. Rotkopf , Jens Weingarten , Jens Kleesiek , Kevin Kröninger

High-precision medical diagnosis relies not only on static imaging features but also on the implicit diagnostic memory experts instantly invoke during image interpretation. We pinpoint a fundamental cognitive misalignment in medical VLMs…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Chunzheng Zhu , Jiaqi Zeng , Junyu Jiang , Jianxin Lin , Yijun Wang

Supervised learning techniques have proven their efficacy in many applications with abundant data. However, applying these methods to medical imaging is challenging due to the scarcity of data, given the high acquisition costs and intricate…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Kevin Arias , Edwin Vargas , Kumar Vijay Mishra , Antonio Ortega , Henry Arguello

Sound and complete algorithms have been proposed to compute identifiable causal queries using the causal structure and data. However, most of these algorithms assume accurate estimation of the data distribution, which is impractical for…

Machine Learning · Computer Science 2024-10-29 Md Musfiqur Rahman , Murat Kocaoglu

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

Healthcare requires AI that is predictive, reliable, and data-efficient. However, recent generative models lack physical foundation and temporal reasoning required for clinical decision support. As scaling language models show diminishing…

Machine Learning · Computer Science 2025-11-21 Mohammad Areeb Qazi , Maryam Nadeem , Mohammad Yaqub

Body composition analysis provides valuable insights into aging, disease progression, and overall health conditions. Due to concerns of radiation exposure, two-dimensional (2D) single-slice computed tomography (CT) imaging has been used…

Computer Vision and Pattern Recognition · Computer Science 2025-01-23 Lianrui Zuo , Xin Yu , Dingjie Su , Kaiwen Xu , Aravind R. Krishnan , Yihao Liu , Shunxing Bao , Fabien Maldonado , Luigi Ferrucci , Bennett A. Landman