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We study the asymptotic behaviors of stochastic cell fate decision between proliferation and differentiation. We propose a model of a self-replicating Langevin system, where cells choose their fate (i.e. proliferation or differentiation)…

Statistical Mechanics · Physics 2017-07-12 Hiroki Yamaguchi , Kyogo Kawaguchi , Takahiro Sagawa

Microorganisms live in environments that inevitably fluctuate between mild and harsh conditions. As harsh conditions may cause extinctions, the rate at which fluctuations occur can shape microbial communities and their diversity, but we…

Populations and Evolution · Quantitative Biology 2021-10-14 Shota Shibasaki , Mauro Mobilia , Sara Mitri

The observation that phenotypic variability is ubiquitous in isogenic populations has led to a multitude of experimental and theoretical studies seeking to probe the causes and consequences of this variability. Whether it be in the context…

Populations and Evolution · Quantitative Biology 2022-02-18 Ethan Levien , Jiseon Min , Jane Kondev , Ariel Amir

An ecosystem is a nonlinear dynamical system, its orbits giving rise to the observed complexity in the system. The diverse components of the ecosystem interact in discrete time to give rise to emergent features that determine the trajectory…

Dynamical Systems · Mathematics 2015-07-29 Sudeepto Bhattacharya , L. M. Saha

Resource-based competition between microorganisms species in continuous culture has been studied extensively both experimentally and theoretically, mostly for bacteria through Monod and and Contois "constant yield" models, or for…

Optimization and Control · Mathematics 2012-08-09 Pierre Masci , Frédéric Grognard , Eric Benoît , Olivier Bernard

We study species abundance in the empirical plant-pollinator mutualistic networks exhibiting broad degree distributions, with uniform intra-group competition assumed, by the Lotka-Volterra equation. The stability of a fixed point is found…

Populations and Evolution · Quantitative Biology 2022-01-25 Hyun Woo Lee , Jae Woo Lee , Deok-Sun Lee

In evolutionary game dynamics, reproductive success increases with the performance in an evolutionary game. If strategy $A$ performs better than strategy $B$, strategy $A$ will spread in the population. Under stochastic dynamics, a single…

Populations and Evolution · Quantitative Biology 2009-03-06 Philipp M. Altrock , Arne Traulsen

In small systems, quantitative discrepancies between stochastic and deterministic descriptions of chemical kinetics can be significant, with their magnitude depending on the specific reaction network. Here, we study the Finke-Watzky…

Chemical Physics · Physics 2025-10-07 Tomasz Bednarek , Jakub Jędrak

Evolutionary game dynamics describes the spreading of successful strategies in a population of reproducing individuals. Typically, the microscopic definition of strategy spreading is stochastic, such that the dynamics becomes deterministic…

Populations and Evolution · Quantitative Biology 2015-05-13 Philipp M. Altrock , Arne Traulsen

We discuss stochastic dynamics of populations of individuals playing games. Our models possess two evolutionarily stable strategies: an efficient one, where a population is in a state with the maximal payoff (fitness) and a risk-dominant…

Populations and Evolution · Quantitative Biology 2007-05-23 Jacek Miekisz

Species introductions to new habitats can cause a decline in the population size of competing native species and consequently also in their genetic diversity. We are interested in why these adverse effects are weak in some cases whereas in…

Populations and Evolution · Quantitative Biology 2013-01-03 Meike J. Wittmann , Martin Hutzenthaler , Wilfried Gabriel , Dirk Metzler

We investigate the stochastic dynamics of entities which are confined to a set of islands, between which they migrate. They are assumed to be one of two types, and in addition to migration, they also reproduce and die. Systems which fall…

Statistical Mechanics · Physics 2014-04-02 George W. A. Constable , Alan J. McKane

Generalizing the cyclically competing three-species model (often referred to as the rock-paper-scissors game), we consider a simple system of population dynamics without spatial structures that involves four species. Unlike the previous…

Populations and Evolution · Quantitative Biology 2011-01-06 Sara O. Case , Clinton H. Durney , Michel Pleimling , R. K. P. Zia

According to the competitive exclusion principle, in a finite ecosystem, extinction occurs naturally when two or more species compete for the same resources. An important question that arises is: when coexistence is not possible, which…

Populations and Evolution · Quantitative Biology 2017-08-16 Marcelo Martins de Oliveira , Ronald Dickman

The influence of competition and additional food on prey-predator dynamics has attracted considerable interest from mathematical biology researchers in recent times. In this study, we consider an additional food provided prey-predator model…

Dynamical Systems · Mathematics 2025-05-01 D Bhanu Prakash , D K K Vamsi

A key goal of systems biology is the predictive mathematical description of gene regulatory circuits. Different approaches are used such as deterministic and stochastic models, models that describe cell growth and division explicitly or…

Molecular Networks · Quantitative Biology 2012-10-12 Rahul Marathe , Veronika Bierbaum , David Gomez , Stefan Klumpp

The purpose of this Note is twofold: First, we introduce the general formalism of evolutionary genetics dynamics involving fitnesses, under both the deterministic and stochastic setups, and chiefly in discrete-time. In the process, we…

Quantitative Methods · Quantitative Biology 2015-05-14 Thierry Huillet

Living species, ranging from bacteria to animals, exist in environmental conditions that exhibit spatial and temporal heterogeneity which requires them to adapt. Risk-spreading through spontaneous phenotypic variations is a known concept in…

Populations and Evolution · Quantitative Biology 2020-04-03 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

We consider the effect of network structure on the evolution of a population. Models of this kind typically consider a population of fixed size and distribution. Here we consider eco-evolutionary dynamics where population size and…

Populations and Evolution · Quantitative Biology 2023-04-05 Karan Pattni , Wajid Ali , Mark Broom , Kieran J Sharkey

Ants are social insects. When the existing nest of an ant colony becomes uninhabitable, the hunt for a new suitable location for migration of the colony begins. Normally, multiple sites may be available as the potential new nest site.…

Adaptation and Self-Organizing Systems · Physics 2021-05-04 Smriti Pradhan , Swayamshree Patra , Debashish Chowdhury
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