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Treatment effect estimation is a fundamental problem in causal inference. We focus on designing efficient randomized controlled trials, to accurately estimate the effect of some treatment on a population of $n$ individuals. In particular,…

Machine Learning · Computer Science 2022-10-14 Raghavendra Addanki , David Arbour , Tung Mai , Cameron Musco , Anup Rao

Medical diagnosis assistant (MDA) aims to build an interactive diagnostic agent to sequentially inquire about symptoms for discriminating diseases. However, since the dialogue records used to build a patient simulator are collected…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Junfan Lin , Keze Wang , Ziliang Chen , Xiaodan Liang , Liang Lin

Randomized experiments are the preferred approach for evaluating the effects of interventions, but they are costly and often yield estimates with substantial uncertainty. On the other hand, in silico experiments leveraging foundation models…

In genomics, differential abundance and expression analyses are complicated by the compositional nature of sequence count data, which reflect only relative-not absolute-abundances or expression levels. Many existing methods attempt to…

Methodology · Statistics 2025-12-16 Won Gu , Francesca Chiaromonte , Justin D. Silverman

Fault diagnosis is critical in many domains, as faults may lead to safety threats or economic losses. In the field of online service systems, operators rely on enormous monitoring data to detect and mitigate failures. Quickly recognizing a…

Software Engineering · Computer Science 2022-06-14 Mingjie Li , Zeyan Li , Kanglin Yin , Xiaohui Nie , Wenchi Zhang , Kaixin Sui , Dan Pei

When constructing a model to estimate the causal effect of a treatment, it is necessary to control for other factors which may have confounding effects. Because the ignorability assumption is not testable, however, it is usually unclear…

Methodology · Statistics 2022-09-07 Spencer Woody , Carlos M. Carvalho , Jared S. Murray

Simulation studies allow us to explore the properties of statistical methods. They provide a powerful tool with a multiplicity of aims; among others: evaluating and comparing new or existing statistical methods, assessing violations of…

Applications · Statistics 2020-05-05 Alessandro Gasparini , Tim P. Morris , Michael J. Crowther

In the context of having an instrumental variable, the standard practice in causal inference begins by targeting an effect of interest and proceeds by formulating assumptions enabling its identification. We turn this around by adhering to…

Statistics Theory · Mathematics 2026-05-25 Carlos García Meixide , Mark J. van der Laan

In order to reduce the cost of experimental evaluation for agents, we introduce a computational theory of evaluation for mini agents: build evaluation model to accelerate the evaluation procedures. We prove upper bounds of generalized error…

Artificial Intelligence · Computer Science 2025-05-19 Hedong Yan

Reversible computation is key in developing new, energy-efficient paradigms, but also in providing forward-only concepts with broader definitions and finer frames of study.Among other fields, the algebraic specification and representation…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-26 Clément Aubert

Randomized controlled trials generate experimental variation that can credibly identify causal effects, but often suffer from limited scale, while observational datasets are large, but often violate desired identification assumptions. To…

Econometrics · Economics 2023-12-27 George Z. Gui

Attrition in survey and field experiments presents a challenge for social science research. Common approaches to deal with this problem -- such as complete case analysis, multiple imputation, and weighting methods -- rely on strong…

Methodology · Statistics 2026-04-13 Xiangyu Song

Causal discovery is to learn cause-effect relationships among variables given observational data and is important for many applications. Existing causal discovery methods assume data sufficiency, which may not be the case in many real world…

Machine Learning · Computer Science 2022-06-20 Zijun Cui , Naiyu Yin , Yuru Wang , Qiang Ji

System-oriented IR evaluations are limited to rather abstract understandings of real user behavior. As a solution, simulating user interactions provides a cost-efficient way to support system-oriented experiments with more realistic…

Information Retrieval · Computer Science 2022-03-25 Timo Breuer , Norbert Fuhr , Philipp Schaer

Confounding bias and selection bias bring two significant challenges to the validity of conclusions drawn from applied causal inference. The latter can stem from informative missingness, such as in cases of attrition. We introduce the…

Methodology · Statistics 2025-03-25 Johan de Aguas , Johan Pensar , Tomás Varnet Pérez , Guido Biele

Monte Carlo simulation studies are at the core of the modern applied, computational, and theoretical statistical literature. Simulation is a broadly applicable research tool, used to collect data on the relative performance of methods or…

Computation · Statistics 2026-01-21 Erik-Jan van Kesteren

As any scientific discipline, the software engineering (SE) research community strives to contribute to the betterment of the target population of our research: software producers and consumers. We will only achieve this betterment if we…

Software Engineering · Computer Science 2025-11-20 Julian Frattini , Hans-Martin Heyn , Robert Feldt , Richard Torkar

Investigating uncertainties in computer simulations can be prohibitive in terms of computational costs, since the simulator needs to be run over a large number of input values. Building an emulator, i.e. a statistical surrogate model of the…

Methodology · Statistics 2022-10-18 Ayao Ehara , Serge Guillas

The paper presents an investigation of estimating treatment effect using different matching methods. The study proposed a new method which is computationally efficient and convenient in implication-'largest caliper matching' and compared…

Applications · Statistics 2018-06-07 Sharif Mahmood

Causal inference is central to many areas of artificial intelligence, including complex reasoning, planning, knowledge-base construction, robotics, explanation, and fairness. An active community of researchers develops and enhances…

Artificial Intelligence · Computer Science 2019-11-05 Amanda Gentzel , Dan Garant , David Jensen