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Generative models capture the true distribution of data, yielding semantically rich representations. Denoising diffusion models (DDMs) exhibit superior generative capabilities, though efficient representation learning for them are lacking.…

Machine Learning · Computer Science 2025-05-12 Limai Jiang , Yunpeng Cai

Artificial intelligence (AI) in healthcare, especially in medical imaging, faces challenges due to data scarcity and privacy concerns. Addressing these, we introduce Med-DDPM, a diffusion model designed for 3D semantic brain MRI synthesis.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-22 Zolnamar Dorjsembe , Hsing-Kuo Pao , Sodtavilan Odonchimed , Furen Xiao

Denoising Diffusion Probabilistic Models (DDPMs) exhibit remarkable capabilities in image generation, with studies suggesting that they can generalize by composing latent factors learned from the training data. In this work, we go further…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Justin Deschenaux , Igor Krawczuk , Grigorios Chrysos , Volkan Cevher

Generative modeling of discrete data underlies important applications spanning text-based agents like ChatGPT to the design of the very building blocks of life in protein sequences. However, application domains need to exert control over…

Denoising diffusion models (DDMs) have led to staggering performance leaps in image generation, editing and restoration. However, existing DDMs use very large datasets for training. Here, we introduce a framework for training a DDM on a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-08 Vladimir Kulikov , Shahar Yadin , Matan Kleiner , Tomer Michaeli

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Diffusion probabilistic models (DPM) have been widely adopted in image-to-image translation to generate high-quality images. Prior attempts at applying the DPM to image super-resolution (SR) have shown that iteratively refining a pure…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Axi Niu , Kang Zhang , Trung X. Pham , Jinqiu Sun , Yu Zhu , In So Kweon , Yanning Zhang

Nowadays, denoising diffusion probabilistic models have been adapted for many image segmentation tasks. However, existing end-to-end models have already demonstrated remarkable capabilities. Rather than using denoising diffusion…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Shi Zhenning , Dong Changsheng , Xie Xueshuo , Pan Bin , He Along , Li Tao

Facial expression generation is one of the most challenging and long-sought aspects of character animation, with many interesting applications. The challenging task, traditionally having relied heavily on digital craftspersons, remains yet…

Computer Vision and Pattern Recognition · Computer Science 2024-04-16 Kaifeng Zou , Sylvain Faisan , Boyang Yu , Sébastien Valette , Hyewon Seo

Generative adversarial networks (GANs) are frequently utilized in astronomy to construct an emulator of numerical simulations. Nevertheless, training GANs can prove to be a precarious task, as they are prone to instability and often lead to…

Instrumentation and Methods for Astrophysics · Physics 2023-11-14 Xiaosheng Zhao , Yuan-Sen Ting , Kangning Diao , Yi Mao

Diffusion models (DMs) have achieved state-of-the-art results for image synthesis tasks as well as density estimation. Applied in the latent space of a powerful pretrained autoencoder (LDM), their immense computational requirements can be…

Computer Vision and Pattern Recognition · Computer Science 2022-10-21 Jeremias Traub

Transformer-based diffusion models have demonstrated remarkable performance at generating high-quality samples. However, our theoretical understanding of the reasons for this success remains limited. For instance, existing models are…

Machine Learning · Computer Science 2026-04-14 Hongkang Li , Hancheng Min , Rene Vidal

Reducing the requirement for densely annotated masks in medical image segmentation is important due to cost constraints. In this paper, we consider the problem of inferring pixel-level predictions of brain lesions by only using image-level…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 Pedro Sanchez , Antanas Kascenas , Xiao Liu , Alison Q. O'Neil , Sotirios A. Tsaftaris

Recent advances in denoising diffusion probabilistic models have shown great success in image synthesis tasks. While there are already works exploring the potential of this powerful tool in image semantic segmentation, its application in…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Xinrong Hu , Yu-Jen Chen , Tsung-Yi Ho , Yiyu Shi

Diffusion models have recently exhibited remarkable abilities to synthesize striking image samples since the introduction of denoising diffusion probabilistic models (DDPMs). Their key idea is to disrupt images into noise through a fixed…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Zijian Zhang , Zhou Zhao , Jun Yu , Qi Tian

Deep generative models have demonstrated remarkable success in medical image synthesis. However, ensuring conditioning faithfulness and high-quality synthetic images for direct or counterfactual generation remains a challenge. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Fangrui Huang , Alan Wang , Binxu Li , Bailey Trang , Ridvan Yesiloglu , Tianyu Hua , Wei Peng , Ehsan Adeli

Semantic segmentation of medical images is pivotal in applications like disease diagnosis and treatment planning. While deep learning has excelled in automating this task, a major hurdle is the need for numerous annotated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Li Zhang , Basu Jindal , Ahmed Alaa , Robert Weinreb , David Wilson , Eran Segal , James Zou , Pengtao Xie

Patients undergoing a mechanical thrombectomy procedure usually have a multi-detector CT (MDCT) scan before and after the intervention. The image quality of the flat panel detector CT (FDCT) present in the intervention room is generally…

Image and Video Processing · Electrical Eng. & Systems 2025-08-28 Hélène Corbaz , Anh Nguyen , Victor Schulze-Zachau , Paul Friedrich , Alicia Durrer , Florentin Bieder , Philippe C. Cattin , Marios N Psychogios

Lung cancer has been one of the leading causes of cancer-related deaths worldwide for years. With the emergence of deep learning, computer-assisted diagnosis (CAD) models based on learning algorithms can accelerate the nodule screening…

Image and Video Processing · Electrical Eng. & Systems 2023-05-03 Xuan Zhao , Benjamin Hou

Denoising Diffusion Probabilistic Models (DDPMs) can generate high-quality samples such as image and audio samples. However, DDPMs require hundreds to thousands of iterations to produce final samples. Several prior works have successfully…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Luping Liu , Yi Ren , Zhijie Lin , Zhou Zhao