English
Related papers

Related papers: Protein sequence classification using natural lang…

200 papers

To understand how well a large language model captures certain semantic or syntactic features, researchers typically apply probing classifiers. However, the accuracy of these classifiers is critical for the correct interpretation of the…

Computation and Language · Computer Science 2023-12-19 Sergey A. Saltykov

Word vectors and Language Models (LMs) pretrained on a large amount of unlabelled data can dramatically improve various Natural Language Processing (NLP) tasks. However, the measure and impact of similarity between pretraining data and…

Computation and Language · Computer Science 2019-05-20 Xiang Dai , Sarvnaz Karimi , Ben Hachey , Cecile Paris

The use of LLMs for natural language processing has become a popular trend in the past two years, driven by their formidable capacity for context comprehension and learning, which has inspired a wave of research from academics and industry…

Computation and Language · Computer Science 2024-04-09 Faren Yan , Peng Yu , Xin Chen

Understanding how individuals with Parkinson's disease (PD) describe cognitive experiences in their daily lives can offer valuable insights into disease-related cognitive and emotional changes. However, extracting such information from…

Computation and Language · Computer Science 2025-11-13 Varada Khanna , Nilay Bhatt , Ikgyu Shin , Sule Tinaz , Yang Ren , Hua Xu , Vipina K. Keloth

The application of Natural Language Processing (NLP) has achieved a high level of relevance in several areas. In the field of software engineering (SE), NLP applications are based on the classification of similar texts (e.g. software…

Software Engineering · Computer Science 2021-12-02 Eliane Maria De Bortoli Fávero , Dalcimar Casanova

Recent studies in Learning to Rank have shown the possibility to effectively distill a neural network from an ensemble of regression trees. This result leads neural networks to become a natural competitor of tree-based ensembles on the…

Machine Learning · Computer Science 2024-10-28 F. M. Nardini , C. Rulli , S. Trani , R. Venturini

Deep neural-network-based language models (LMs) are increasingly applied to large-scale protein sequence data to predict protein function. However, being largely black-box models and thus challenging to interpret, current protein LM…

Quantitative Methods · Quantitative Biology 2024-08-06 Mai Ha Vu , Rahmad Akbar , Philippe A. Robert , Bartlomiej Swiatczak , Victor Greiff , Geir Kjetil Sandve , Dag Trygve Truslew Haug

Motivation: Protein embedding, which represents proteins as numerical vectors, is a crucial step in various learning-based protein annotation/classification problems, including gene ontology prediction, protein-protein interaction…

Genomics · Quantitative Biology 2024-05-21 Jiayu Shang , Cheng Peng , Yongxin Ji , Jiaojiao Guan , Dehan Cai , Xubo Tang , Yanni Sun

Supervised fine-tuning (SFT) is a standard approach for adapting large language models to specialized domains, yet its application to protein sequence modeling and protein language models (PLMs) remains ad hoc. This is in part because…

Machine Learning · Computer Science 2025-12-11 Amin Tavakoli , Raswanth Murugan , Ozan Gokdemir , Arvind Ramanathan , Frances Arnold , Anima Anandkumar

Vision-language models (VLMs) have made significant progress in image classification by training with large-scale paired image-text data. Their performances largely depend on the prompt quality. While recent methods show that visual…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Xiangyan Qu , Gaopeng Gou , Jiamin Zhuang , Jing Yu , Kun Song , Qihao Wang , Yili Li , Gang Xiong

Model pruning technique is vital for accelerating large language models by reducing their size and computational requirements. However, the generalizability of existing pruning methods across diverse datasets and tasks remains unclear.…

Computation and Language · Computer Science 2025-03-04 Yizhuo Ding , Xinwei Sun , Yanwei Fu , Guosheng Hu

Fine-tuning Pre-trained protein language models (PLMs) has emerged as a prominent strategy for enhancing downstream prediction tasks, often outperforming traditional supervised learning approaches. As a widely applied powerful technique in…

Computation and Language · Computer Science 2024-04-24 Yang Tan , Mingchen Li , Bingxin Zhou , Bozitao Zhong , Lirong Zheng , Pan Tan , Ziyi Zhou , Huiqun Yu , Guisheng Fan , Liang Hong

We provide a thorough treatment of one-class classification with hyperparameter optimisation for five data descriptors: Support Vector Machine (SVM), Nearest Neighbour Distance (NND), Localised Nearest Neighbour Distance (LNND), Local…

Machine Learning · Computer Science 2022-08-04 Oliver Urs Lenz , Daniel Peralta , Chris Cornelis

This study addressed the complex task of sentiment analysis on a dataset of 119,988 original tweets from Weibo using a Convolutional Neural Network (CNN), offering a new approach to Natural Language Processing (NLP). The data, sourced from…

Computation and Language · Computer Science 2023-07-14 Yufei Xie , Rodolfo C. Raga

We propose a general method to break down a main complex task into a set of intermediary easier sub-tasks, which are formulated in natural language as binary questions related to the final target task. Our method allows for representing…

Computation and Language · Computer Science 2024-02-02 Felipe Urrutia , Cristian Buc , Valentin Barriere

Artificial neural networks (ANNs) have gained a well-deserved popularity among machine learning tools upon their recent successful applications in image- and sound processing and classification problems. ANNs have also been applied for…

Biomolecules · Quantitative Biology 2017-04-03 Balazs Szalkai , Vince Grolmusz

Pattern learning in an important problem in Natural Language Processing (NLP). Some exhaustive pattern learning (EPL) methods (Bod, 1992) were proved to be flawed (Johnson, 2002), while similar algorithms (Och and Ney, 2004) showed great…

Artificial Intelligence · Computer Science 2011-04-21 Libin Shen

Understanding the relationships between protein sequence, structure and function is a long-standing biological challenge with manifold implications from drug design to our understanding of evolution. Recently, protein language models have…

Quantitative Methods · Quantitative Biology 2024-01-29 Dexiong Chen , Philip Hartout , Paolo Pellizzoni , Carlos Oliver , Karsten Borgwardt

Efficient text classification is essential for handling the increasing volume of academic publications. This study explores the use of pre-trained language models (PLMs), including BERT, SciBERT, BioBERT, and BlueBERT, fine-tuned on the Web…

Computation and Language · Computer Science 2025-09-09 Zhyar Rzgar K Rostam , Gábor Kertész

The prediction of amyloidogenicity in peptides and proteins remains a focal point of ongoing bioinformatics. The crucial step in this field is to apply advanced computational methodologies. Many recent approaches to predicting…

Machine Learning · Computer Science 2025-08-19 Zohra Yagoub , Hafida Bouziane