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Computational pathology needs whole-slide image (WSI) foundation models that transfer across diverse clinical tasks, yet current approaches remain largely slide-centric, often depend on private data and expensive paired-report supervision,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Yousef Kotp , Vincent Quoc-Huy Trinh , Christopher Pal , Mahdi S. Hosseini

Advancements in artificial intelligence have driven the development of numerous pathology foundation models capable of extracting clinically relevant information. However, there is currently limited literature independently evaluating these…

This study addresses the essential task of medical image segmentation, which involves the automatic identification and delineation of anatomical structures and pathological regions in medical images. Accurate segmentation is crucial in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Seyedeh Sahar Taheri Otaghsara , Reza Rahmanzadeh

Intensive care unit (ICU) data are highly irregular, heterogeneous, and temporally fragmented, posing challenges for generalizable clinical prediction. We present PULSE-ICU, a self-supervised foundation model that learns event-level ICU…

Machine Learning · Computer Science 2025-12-01 Sejeong Jang , Joo Heung Yoon , Hyo Kyung Lee

Fully supervised segmentation methods require a large training cohort of already segmented images, providing information at the pixel level of each image. We present a method to automatically segment and model pathologies in medical images,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-22 Simon Andermatt , Antal Horváth , Simon Pezold , Philippe Cattin

We propose a deep autoencoder with graph topology inference and filtering to achieve compact representations of unorganized 3D point clouds in an unsupervised manner. Many previous works discretize 3D points to voxels and then use…

Computer Vision and Pattern Recognition · Computer Science 2020-02-19 Siheng Chen , Chaojing Duan , Yaoqing Yang , Duanshun Li , Chen Feng , Dong Tian

We share our recent findings in an attempt to train a universal segmentation network for various cell types and imaging modalities. Our method was built on the generalized U-Net architecture, which allows the evaluation of each component…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Tianqi Guo , Yin Wang , Luis Solorio , Jan P. Allebach

Noninvasive optical imaging modalities can probe patient's tissue in 3D and over time generate gigabytes of clinically relevant data per sample. There is a need for AI models to analyze this data and assist clinical workflow. The lack of…

Computed tomography (CT) and clinical numeric data are essential modalities for cancer evaluation, but building large-scale multimodal training datasets for developing medical foundation models remains challenging due to the structural…

Computer Vision and Pattern Recognition · Computer Science 2025-01-24 Daeun Jung , Jaehyeok Jang , Sooyoung Jang , Yu Rang Park

Foundation models, large-scale, pre-trained deep-learning models adapted to a wide range of downstream tasks have gained significant interest lately in various deep-learning problems undergoing a paradigm shift with the rise of these…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Bobby Azad , Reza Azad , Sania Eskandari , Afshin Bozorgpour , Amirhossein Kazerouni , Islem Rekik , Dorit Merhof

Pathology foundation models learn morphological representations through self-supervised pretraining on large-scale whole-slide images, yet they do not explicitly capture the underlying molecular state of the tissue. Spatial transcriptomics…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Minsoo Lee , Jonghyun Kim , Juseung Yun , Sunwoo Yu , Jongseong Jang

The recent surge of foundation models in computer vision and natural language processing opens up perspectives in utilizing multi-modal clinical data to train large models with strong generalizability. Yet pathological image datasets often…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Yunkun Zhang , Jin Gao , Mu Zhou , Xiaosong Wang , Yu Qiao , Shaoting Zhang , Dequan Wang

Image models are central to all image processing tasks. The great advancements in digital image processing would not have been made possible without powerful models which, themselves, have evolved over time. In the past decade, patch-based…

Image and Video Processing · Electrical Eng. & Systems 2019-12-10 Davood Karimi

Artificial Intelligence (AI) has the potential to revolutionize diagnosis and segmentation in medical imaging. However, development and clinical implementation face multiple challenges including limited data availability, lack of…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Zelong Liu , Andrew Tieu , Nikhil Patel , Georgios Soultanidis , Louisa Deyer , Ying Wang , Sean Huver , Alexander Zhou , Yunhao Mei , Zahi A. Fayad , Timothy Deyer , Xueyan Mei

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Unsupervised anomaly detection has gained significant attention in the field of medical imaging due to its capability of relieving the costly pixel-level annotation. To achieve this, modern approaches usually utilize generative models to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Rui Xu , Yunke Wang , Bo Du

We propose a novel system for unsupervised skeleton-based action recognition. Given inputs of body keypoints sequences obtained during various movements, our system associates the sequences with actions. Our system is based on an…

Computer Vision and Pattern Recognition · Computer Science 2019-12-02 Kun Su , Xiulong Liu , Eli Shlizerman

Understanding the biological mechanisms of disease is crucial for medicine, and in particular, for drug discovery. AI-powered analysis of genome-scale biological data holds great potential in this regard. The increasing availability of…

The majority of AI models in imaging and vision are customized to perform on specific high-precision task. However, this strategy is inefficient for applications with a series of modular tasks, since each requires a mapping into a disparate…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Jing Li , Oskar Bartosz , Chengyu Wang , Michal Wnuczynski , Dilshan Godaliyadda , Michael Polley

Autoencoders are unsupervised deep learning models used for learning representations. In literature, autoencoders have shown to perform well on a variety of tasks spread across multiple domains, thereby establishing widespread…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Maneet Singh , Shruti Nagpal , Mayank Vatsa , Richa Singh , Afzel Noore