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Model merging offers a scalable alternative to multi-task learning but often yields suboptimal performance on classification tasks. We attribute this degradation to a geometric misalignment between the merged encoder and static…

Machine Learning · Computer Science 2026-02-03 Fanshuang Kong , Richong Zhang , Zhijie Nie , Hang Zhou , Ziqiao Wang , Qiang Sun , Chunming Hu

Zeroth-order optimization (ZO) has been a powerful framework for solving black-box problems, which estimates gradients using zeroth-order data to update variables iteratively. The practical applicability of ZO critically depends on the…

Optimization and Control · Mathematics 2026-03-03 Ruiyang Jin , Yuke Zhou , Yujie Tang , Jie Song , Siyang Gao

Coarse-graining (CG) of molecular simulations simplifies the particle representation by grouping selected atoms into pseudo-beads and drastically accelerates simulation. However, such CG procedure induces information losses, which makes…

Machine Learning · Computer Science 2022-06-20 Wujie Wang , Minkai Xu , Chen Cai , Benjamin Kurt Miller , Tess Smidt , Yusu Wang , Jian Tang , Rafael Gómez-Bombarelli

A parameterization strategy for molecular models on the basis of force fields is proposed, which allows a rapid development of models for small molecules by using results from quantum mechanical (QM) ab initio calculations and thermodynamic…

Chemical Physics · Physics 2009-04-22 Bernhard Eckl , Jadran Vrabec , Hans Hasse

Learning representations through deep generative modeling is a powerful approach for dynamical modeling to discover the most simplified and compressed underlying description of the data, to then use it for other tasks such as prediction.…

Machine Learning · Computer Science 2022-03-01 Bahar Azari , Deniz Erdoğmuş

Accurate rotation estimation is at the heart of robot perception tasks such as visual odometry and object pose estimation. Deep neural networks have provided a new way to perform these tasks, and the choice of rotation representation is an…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Valentin Peretroukhin , Matthew Giamou , David M. Rosen , W. Nicholas Greene , Nicholas Roy , Jonathan Kelly

We present a new approach to 3D object representation where a neural network encodes the geometry of an object directly into the weights and biases of a second 'mapping' network. This mapping network can be used to reconstruct an object by…

Machine Learning · Computer Science 2020-04-07 Eric Mitchell , Selim Engin , Volkan Isler , Daniel D Lee

Unsupervised contrastive learning for indoor-scene point clouds has achieved great successes. However, unsupervised learning point clouds in outdoor scenes remains challenging because previous methods need to reconstruct the whole scene and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Runjian Chen , Yao Mu , Runsen Xu , Wenqi Shao , Chenhan Jiang , Hang Xu , Zhenguo Li , Ping Luo

Considering recent advancements and successes in the development of efficient quantum algorithms for electronic structure calculations --- alongside impressive results using machine learning techniques for computation --- hybridizing…

Quantum Physics · Physics 2018-10-24 Rongxin Xia , Sabre Kais

Many settings in machine learning require the selection of a rotation representation. However, choosing a suitable representation from the many available options is challenging. This paper acts as a survey and guide through rotation…

Machine Learning · Computer Science 2025-03-26 A. René Geist , Jonas Frey , Mikel Zhobro , Anna Levina , Georg Martius

Ground-state 3D geometries of molecules are essential for many molecular analysis tasks. Modern quantum mechanical methods can compute accurate 3D geometries but are computationally prohibitive. Currently, an efficient alternative to…

Chemical Physics · Physics 2023-05-24 Zhao Xu , Yaochen Xie , Youzhi Luo , Xuan Zhang , Xinyi Xu , Meng Liu , Kaleb Dickerson , Cheng Deng , Maho Nakata , Shuiwang Ji

The field of geometric deep learning has had a profound impact on the development of innovative and powerful graph neural network architectures. Disciplines such as computer vision and computational biology have benefited significantly from…

Machine Learning · Computer Science 2023-04-28 Alex Morehead , Jianlin Cheng

Accurately predicting response properties of molecules such as the dynamic polarizability and hyperpolarizability using quantum mechanics has been a long-standing challenge with widespread applications in material and drug design. Classical…

Chemical Physics · Physics 2020-09-01 Xiaoxia Cai , Wei-Hai Fang , Heng Fan , Zhendong Li

Abstracting complex 3D shapes with parsimonious part-based representations has been a long standing goal in computer vision. This paper presents a learning-based solution to this problem which goes beyond the traditional 3D cuboid…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Despoina Paschalidou , Ali Osman Ulusoy , Andreas Geiger

Momentum-based gradients are essential for optimizing advanced machine learning models, as they not only accelerate convergence but also advance optimizers to escape stationary points. While most state-of-the-art momentum techniques utilize…

Machine Learning · Computer Science 2025-05-20 Wei Zhang , Arif Hassan Zidan , Afrar Jahin , Yu Bao , Tianming Liu

The ongoing energy crisis has underscored the urgent need for energy-efficient materials with high energy utilization efficiency, prompting a surge in research into organic compounds due to their environmental compatibility, cost-effective…

Chemical Physics · Physics 2025-07-24 Qi Ou , Hongshuai Wang , Minyang Zhuang , Shangqian Chen , Lele Liu , Ning Wang , Zhifeng Gao

Machine-learning of atomic-scale properties amounts to extracting correlations between structure, composition and the quantity that one wants to predict. Representing the input structure in a way that best reflects such correlations makes…

Chemical Physics · Physics 2021-02-02 Michael J. Willatt , Félix Musil , Michele Ceriotti

Molecule pretraining has quickly become the go-to schema to boost the performance of AI-based drug discovery. Naturally, molecules can be represented as 2D topological graphs or 3D geometric point clouds. Although most existing pertaining…

Machine Learning · Computer Science 2025-02-10 Shengchao Liu , Weitao Du , Zhiming Ma , Hongyu Guo , Jian Tang

The latest research of the proportionality of atomic weights of chemical elements made it possible to obtain 3 x 3 matrices for the calculation of information coefficients of proportionality Ip that can be used for 3D modeling of the…

General Physics · Physics 2012-07-20 Mikhail M. Labushev

Gradient-based algorithms, popular strategies to optimization problems, are essential for many modern machine-learning techniques. Theoretically, extreme points of certain cost functions can be found iteratively along the directions of the…

Quantum Physics · Physics 2021-04-07 Keren Li , Pan Gao , Shijie Wei , Jiancun Gao , Guilu Long
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