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Deep learning forms a hierarchical network structure for representation of multiple input features. The adaptive structural learning method of Deep Belief Network (DBN) can realize a high classification capability while searching the…
In this paper we address the problem of protein classification starting from a multi-view 2D representation of proteins. From each 3D protein structure, a large set of 2D projections is generated using the protein visualization software…
Link prediction plays an important role in network analysis and applications. Recently, approaches for link prediction have evolved from traditional similarity-based algorithms into embedding-based algorithms. However, most existing…
This paper proposes a novel deep reinforcement learning (RL) architecture, called Value Prediction Network (VPN), which integrates model-free and model-based RL methods into a single neural network. In contrast to typical model-based RL…
Deep learning has deeply influenced protein science, enabling breakthroughs in predicting protein properties, higher-order structures, and molecular interactions. This paper introduces DeepProtein, a comprehensive and user-friendly deep…
Model reprogramming adapts pretrained models to downstream tasks by modifying only the input and output spaces. Visual reprogramming (VR) is one instance for vision tasks that adds a trainable noise pattern (i.e., a visual prompt) to input…
Click-through rate prediction is an essential task in industrial applications, such as online advertising. Recently deep learning based models have been proposed, which follow a similar Embedding\&MLP paradigm. In these methods large scale…
Accurately predicting individual neurons' responses and spatial functional properties in complex visual tasks remains a key challenge in understanding neural computation. Existing whole-brain connectome models of Drosophila often rely on…
The deep reinforcement learning (DRL) based Volt-VAR optimization (VVO) methods have been widely studied for active distribution networks (ADNs). However, most of them lack safety guarantees in terms of power injection uncertainties due to…
This study considers multiple reconfigurable intelligent surfaces (RISs)-aided multiuser downlink systems with the goal of jointly optimizing the transmitter precoding and RIS phase shift matrix to maximize spectrum efficiency. Unlike prior…
Federated Learning (FL) is a distributed learning technique that maintains data privacy by providing a decentralized training method for machine learning models using distributed big data. This promising Federated Learning approach has also…
We describe a machine learning method for predicting the value of a real-valued function, given the values of multiple input variables. The method induces solutions from samples in the form of ordered disjunctive normal form (DNF) decision…
Message-passing graph neural networks (MPNNs) and structural features (SFs) are cornerstones for the link prediction task. However, as a common and intuitive mode of understanding, the potential of visual perception has been overlooked in…
Learning effective protein representations is critical in a variety of tasks in biology such as predicting protein functions. Recent sequence representation learning methods based on Protein Language Models (PLMs) excel in sequence-based…
We present a novel dual-head deep learning architecture for protein-protein interaction modeling that enables simultaneous prediction of binding affinity ($\Delta G$) and mutation-induced affinity changes ($\Delta\Delta G$) using only…
Large Vision-Language Models (LVLMs) or multimodal large language models represent a significant advancement in artificial intelligence, enabling systems to understand and generate content across both visual and textual modalities. While…
The temporal dynamics of a complex system such as a social network or a communication network can be studied by understanding the patterns of link appearance and disappearance over time. A critical task along this understanding is to…
A random vector functional link network (RVFL) is widely used as a universal approximator for classification and regression problems. The big advantage of RVFL is fast training without backpropagation. This is because the weights and biases…
Despite significant progress in static protein structure collection and prediction, the dynamic behavior of proteins, one of their most vital characteristics, has been largely overlooked in prior research. This oversight can be attributed…
We discuss probabilistic methods for predicting protein functions from protein-protein interaction networks. Previous work based on Markov Randon Fields is extended and compared to a general machine-learning theoretic approach. Using actual…