Related papers: Multiview Random Vector Functional Link Network fo…
The classification performance of the random vector functional link (RVFL), a randomized neural network, has been widely acknowledged. However, due to its shallow learning nature, RVFL often fails to consider all the relevant information…
Multimodal protein features play a crucial role in protein function prediction. However, these features encompass a wide range of information, ranging from structural data and sequence features to protein attributes and interaction…
Neural networks have been successfully employed in various domains such as classification, regression and clustering, etc. Generally, the back propagation (BP) based iterative approaches are used to train the neural networks, however, it…
In this paper, we propose a deep learning framework based on randomized neural network. In particular, inspired by the principles of Random Vector Functional Link (RVFL) network, we present a deep RVFL network (dRVFL) with stacked layers.…
In this paper, we first introduce batch normalization to the edRVFL network. This re-normalization method can help the network avoid divergence of the hidden features. Then we propose novel variants of Ensemble Deep Random Vector Functional…
Protein representation learning is critical in various tasks in biology, such as drug design and protein structure or function prediction, which has primarily benefited from protein language models and graph neural networks. These models…
DNA-binding proteins are a class of proteins which have a specific or general affinity to DNA and include three important components: transcription factors; nucleases, and histones. DNA-binding proteins also perform important roles in many…
Identifying DNA- (DBPs) and RNA-binding proteins (RBPs) is crucial for the understanding of cell function, molecular interactions as well as regulatory functions. Owing to their high similarity, most of the existing approaches face…
Proteins are the basic building blocks of life. They usually perform functions by folding to a particular structure. Understanding the folding process could help the researchers to understand the functions of proteins and could also help to…
Predicting protein secondary structure is essential for understanding protein function and advancing drug discovery. However, the intricate sequence-structure relationship poses significant challenges for accurate modeling. To address…
Protein (receptor)--ligand interaction prediction is a critical component in computer-aided drug design, significantly influencing molecular docking and virtual screening processes. Despite the development of numerous scoring functions in…
Composed of amino acid chains that influence how they fold and thus dictating their function and features, proteins are a class of macromolecules that play a central role in major biological processes and are required for the structure,…
Randomized neural networks (NNs) are an interesting alternative to conventional NNs that are more used for data modeling. The random vector functional-link (RVFL) network is an established and theoretically well-grounded randomized learning…
Multi-View Representation Learning (MVRL) aims to derive a unified representation from multi-view data by leveraging shared and complementary information across views. However, when views are irregularly missing, the incomplete data can…
This paper is concerned with multi-view reinforcement learning (MVRL), which allows for decision making when agents share common dynamics but adhere to different observation models. We define the MVRL framework by extending partially…
Protein-RNA interactions are of vital importance to a variety of cellular activities. Both experimental and computational techniques have been developed to study the interactions. Due to the limitation of the previous database, especially…
This paper presents a deep learning-based framework for predicting the dynamic performance of suspension systems in multi-axle vehicles, emphasizing the integration of machine learning with traditional vehicle dynamics modeling. A…
The performance of video prediction has been greatly boosted by advanced deep neural networks. However, most of the current methods suffer from large model sizes and require extra inputs, e.g., semantic/depth maps, for promising…
Predicting accurate protein-ligand binding affinity is important in drug discovery but remains a challenge even with computationally expensive biophysics-based energy scoring methods and state-of-the-art deep learning approaches. Despite…
Stochastic processes that involve the creation of objects and relations over time are widespread, but relatively poorly studied. For example, accurate fault diagnosis in factory assembly processes requires inferring the probabilities of…