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Persistence and permanence are properties of dynamical systems that describe the long-term behavior of the solutions, and in particular specify whether positive solutions approach the boundary of the positive orthant. Mass-action systems…

Dynamical Systems · Mathematics 2011-03-03 Gheorghe Craciun , Fedor Nazarov , Casian Pantea

Many physical systems--from mechanical lattices and electrical circuits to biological tissues and architected metamaterials--can be understood as networks transmitting physical quantities. We present a unified mathematical framework for…

Soft Condensed Matter · Physics 2025-08-07 José M. Ortiz-Tavárez , William Stephenson , Xiaoming Mao

This paper studies the robustness of a PDE backstepping delay-compensated boundary controller for a reaction-diffusion partial differential equation (PDE) with respect to a nominal delay subject to stochastic error disturbance. The…

Optimization and Control · Mathematics 2024-01-22 Dandan Guan , Jie Qi , Mamadou Diagne

Previous studies have inferred robust stability of reaction networks by utilizing linear programs or iterative algorithms. Such algorithms become tedious or computationally infeasible for large networks. In addition, they operate like…

Optimization and Control · Mathematics 2023-02-13 M. Ali Al-Radhawi

Active agents with time-delayed interactions arise naturally in various real-world systems, such as biological systems, transportation networks and robotic swarms. Such systems are typically modeled as Delay Differential Equations (DDEs)…

Dynamical Systems · Mathematics 2025-09-03 Yu Wang , Andreas Amann , Jinde Cao , Jürgen Kurths , Serhiy Yanchuk

This paper studies the relations among system parameters, uniqueness, and stability of equilibria, for kinetic systems given in the form of polynomial ODEs. Such models are commonly used to describe the dynamics of nonnegative systems, with…

Molecular Networks · Quantitative Biology 2016-11-14 Antonio A. Alonso , Gabor Szederkenyi

The spatially distributed reaction networks are indispensable for the understanding of many important phenomena concerning the development of organisms, coordinated cell behavior, and pattern formation. The purpose of this brief discussion…

Optimization and Control · Mathematics 2013-05-15 Marko Seslija , Jacquelien M. A. Scherpen , Arjan van der Schaft

We consider Markov jump processes on a graph described by a rate matrix that depends on various control parameters. We derive explicit expressions for the static responses of edge currents and steady-state probabilities. We show that they…

Statistical Mechanics · Physics 2024-08-28 Timur Aslyamov , Massimiliano Esposito

We present a systematic mathematical analysis of the qualitative steady-state response to rate perturbations in large classes of reaction networks. This includes multimolecular reactions and allows for catalysis, enzymatic reactions,…

Dynamical Systems · Mathematics 2017-11-22 Bernhard Brehm , Bernold Fiedler

Autocatalytic Sets are reaction networks theorised as networks at the basis of life. Their main feature is the ability of spontaneously emerging and self-reproducing. The Reflexively and Food-generated theory provides a formal definition of…

Molecular Networks · Quantitative Biology 2020-10-19 Alessandro Ravoni

We consider a class of non-linear dynamics on a graph that contains and generalizes various models from network systems and control and study convergence to uniform agreement states using gradient methods. In particular, under the…

Dynamical Systems · Mathematics 2016-08-10 Herbert Mangesius , Jean-Charles Delvenne , Sanjoy K. Mitter

We consider a continuous-time stochastic model of spiking neurons. In this model, we have a finite or countable number of neurons which are vertices in some graph $G$ where the edges indicate the synaptic connection between them. We focus…

Probability · Mathematics 2020-10-27 Morgan André , Léo Planche

For chemical reaction networks described by a master equation, we define energy and entropy on a stochastic trajectory and develop a consistent nonequilibrium thermodynamic description along a single stochastic trajectory of reaction…

Statistical Mechanics · Physics 2009-11-11 Tim Schmiedl , Udo Seifert

This work addresses multistationarity of fully open reaction networks equipped with mass action kinetics. We improve upon the existing results relating existence of positive feedback loops in a reaction network and multistationarity; and we…

Molecular Networks · Quantitative Biology 2025-11-11 Shenghao Yao , AmirHosein Sadeghimanesh , Matthew England

We consider global dynamics of reaction systems as introduced by Ehrenfeucht and Rozenberg. The dynamics is represented by a directed graph, the so-called transition graph, and two reaction systems are considered equivalent if their…

Combinatorics · Mathematics 2018-08-07 Daniela Genova , Hendrik Jan Hoogeboom , Nataša Jonoska

Delays are an important phenomenon arising in a wide variety of real world systems. They occur in biological models because of diffusion effects or as simplifying modeling elements. We propose here to consider delayed stochastic reaction…

Optimization and Control · Mathematics 2020-04-27 Corentin Briat , Mustafa Khammash

We study general linear transport-reaction systems on an arbitrary dimensional hypercube with periodic boundary conditions. Transport-reaction systems are often used to model the finite speed movement and interaction of particles, bacteria…

Analysis of PDEs · Mathematics 2022-10-04 Benedikt Geiger

A reaction network is a chemical system involving multiple reactions and chemical species. Stochastic models of such networks treat the system as a continuous time Markov chain on the number of molecules of each species with reactions as…

Probability · Mathematics 2007-05-23 Karen Ball , Thomas G. Kurtz , Lea Popovic , Greg Rempala

The connection between network topology and stability remains unclear. General approaches that clarify this relationship and allow for more efficient stability analysis would be desirable. Inspired by chemical reaction networks, I…

Chaotic Dynamics · Physics 2013-09-27 Ali Kinkhabwala

A chemical reaction network (CRN) is composed of reactions that can be seen as interactions among entities called species, which exist within the system. Endowed with kinetics, CRN has a corresponding set of ordinary differential equations…

Dynamical Systems · Mathematics 2021-04-20 Bryan S. Hernandez , Ralph John L. De la Cruz