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The recent advancements in large foundation models have driven the success of open-set image segmentation, a task focused on segmenting objects beyond predefined categories. Among various prompt types (such as points, boxes, texts, and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Xiaoqi Wang , Clint Sebastian , Wenbin He , Liu Ren

Multi-rater annotations commonly occur when medical images are independently annotated by multiple experts (raters). In this paper, we tackle two challenges arisen in multi-rater annotations for medical image segmentation (called ambiguous…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Jinhong Wang , Yi Cheng , Jintai Chen , Hongxia Xu , Danny Chen , Jian Wu

In digital pathology, precise nuclei segmentation is pivotal yet challenged by the diversity of tissue types, staining protocols, and imaging conditions. Recently, the segment anything model (SAM) revealed overwhelming performance in…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Zhen Chen , Qing Xu , Xinyu Liu , Yixuan Yuan

The performance of deep segmentation models often degrades due to distribution shifts in image intensities between the training and test data sets. This is particularly pronounced in multi-centre studies involving data acquired using…

Image and Video Processing · Electrical Eng. & Systems 2021-08-03 Zhendong Liu , Van Manh , Xin Yang , Xiaoqiong Huang , Karim Lekadir , Víctor Campello , Nishant Ravikumar , Alejandro F Frangi , Dong Ni

Although new vision foundation models such as Segment Anything Model 2 (SAM2) have significantly enhanced zero-shot image segmentation capabilities, reliance on human-provided prompts poses significant challenges in adapting SAM2 to medical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Yang Xing , Jiong Wu , Yuheng Bu , Kuang Gong

Surgical image segmentation is highly challenging, primarily due to scarcity of annotated data. Generalist prompted segmentation models like the Segment-Anything Model (SAM) can help tackle this task, but because they require image-specific…

Computer Vision and Pattern Recognition · Computer Science 2025-07-16 Aditya Murali , Farahdiba Zarin , Adrien Meyer , Pietro Mascagni , Didier Mutter , Nicolas Padoy

Deep learning-based medical image segmentation typically requires large amount of labeled data for training, making it less applicable in clinical settings due to high annotation cost. Semi-supervised learning (SSL) has emerged as an…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Yichi Zhang , Bohao Lv , Le Xue , Wenbo Zhang , Yuchen Liu , Yu Fu , Yuan Cheng , Yuan Qi

Due to low tissue contrast, irregular object appearance, and unpredictable location variation, segmenting the objects from different medical imaging modalities (e.g., CT, MR) is considered as an important yet challenging task. In this…

Computer Vision and Pattern Recognition · Computer Science 2018-05-10 Jinquan Sun , Yinghuan Shi , Yang Gao , Lei Wang , Luping Zhou , Wanqi Yang , Dinggang Shen

Foundation models like the segment anything model require high-quality manual prompts for medical image segmentation, which is time-consuming and requires expertise. SAM and its variants often fail to segment structures in ultrasound (US)…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Assefa Seyoum Wahd , Banafshe Felfeliyan , Yuyue Zhou , Shrimanti Ghosh , Adam McArthur , Jiechen Zhang , Jacob L. Jaremko , Abhilash Hareendranathan

Referring image segmentation (RIS) aims to precisely segment referents in images through corresponding natural language expressions, yet relying on cost-intensive mask annotations. Weakly supervised RIS thus learns from image-text pairs to…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 Qiyuan Dai , Sibei Yang

The remarkable capabilities of the Segment Anything Model (SAM) for tackling image segmentation tasks in an intuitive and interactive manner has sparked interest in the design of effective visual prompts. Such interest has led to the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jorge Quesada , Zoe Fowler , Mohammad Alotaibi , Mohit Prabhushankar , Ghassan AlRegib

Foundation models have rapidly evolved and have achieved significant accomplishments in computer vision tasks. Specifically, the prompt mechanism conveniently allows users to integrate image prior information into the model, making it…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Handi Deng , Yucheng Zhou , Jiaxuan Xiang , Liujie Gu , Yan Luo , Hai Feng , Mingyuan Liu , Cheng Ma

Neural networks pre-trained on a self-supervision scheme have become the standard when operating in data rich environments with scarce annotations. As such, fine-tuning a model to a downstream task in a parameter-efficient but effective…

Computer Vision and Pattern Recognition · Computer Science 2022-11-18 Marc Fischer , Alexander Bartler , Bin Yang

Foundation models have shown strong performance in multi-object segmentation with visual prompts, yet histopathology images remain challenging due to high cellular density, heterogeneity, and the gap between pixel-level supervision and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yonghuang Wu , Wenwen Zeng , Xuan Xie , Chengqian Zhao , Guoqing Wu , Jinhua Yu

Cell segmentation is a fundamental task in microscopy image analysis. Several foundation models for cell segmentation have been introduced, virtually all of them are extensions of Segment Anything Model (SAM), improving it for microscopy…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Anwai Archit , Constantin Pape

Medical image segmentation is vital for clinical diagnosis, yet current deep learning methods often demand extensive expert effort, i.e., either through annotating large training datasets or providing prompts at inference time for each new…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Xingjian Li , Qifeng Wu , Adithya S. Ubaradka , Yiran Ding , Colleen Que , Runmin Jiang , Jianhua Xing , Tianyang Wang , Min Xu

Interactive segmentation model leverages prompts from users to produce robust segmentation. This advancement is facilitated by prompt engineering, where interactive prompts serve as strong priors during test-time. However, this is an…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Rushi Jiao , Yichi Zhang , Le Ding , Rong Cai , Jicong Zhang

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

The Segment Anything Model (SAM) has exhibited outstanding performance in various image segmentation tasks. Despite being trained with over a billion masks, SAM faces challenges in mask prediction quality in numerous scenarios, especially…

Computer Vision and Pattern Recognition · Computer Science 2024-01-25 Zhaozhi Xie , Bochen Guan , Weihao Jiang , Muyang Yi , Yue Ding , Hongtao Lu , Lei Zhang
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