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The existence of travelling waves for a model of concentration waves of bacteria is investigated. The model consists in a kinetic equation for the biased motion of cells following a run-and-tumble process, coupled with two…

Analysis of PDEs · Mathematics 2016-07-05 Vincent Calvez

A fully parabolic chemotaxis model of Keller-Segel type with local sensing is considered. The system features a signal-dependent asymptotically non-degenerate motility function, which accounts for a repulsion-dominated chemotaxis. Global…

Analysis of PDEs · Mathematics 2024-11-19 Jie Jiang , Philippe Laurençot

The phenomenon where cells with elongated protrusions, such as neurons, communicate by contacting other cells and arrange themselves appropriately is termed cell sorting through haptotaxis. This phenomenon is described by partial…

Analysis of PDEs · Mathematics 2026-01-01 Hiroshi Ishii , Hideki Murakawa , Yoshitaro Tanaka

Convergence of solutions to a partially diffusive chemotaxis system with indirect signal production and phenotype switching is shown in a two-dimensional setting when the switching rate increases to infinity, thereby providing a rigorous…

Analysis of PDEs · Mathematics 2024-10-10 Philippe Laurençot , Christian Stinner

We present a discrete model of chemotaxis whereby cells responding to a chemoattractant are seen as individual agents whose movement is described through a set of rules that result in a biased random walk. In order to take into account…

Analysis of PDEs · Mathematics 2020-03-27 Federica Bubba , Tommaso Lorenzi , Fiona R Macfarlane

The flux limited Keller-Segel (FLKS) system is a macroscopic model describing bacteria motion by chemotaxis which takes into account saturation of the velocity. The hyper-bolic form and some special parabolic forms have been derived from…

Analysis of PDEs · Mathematics 2018-01-23 Benoît Perthame , Nicolas Vauchelet , Zhian Wang

The purpose of this work is the study of \textit{chemotaxis} and how to model it through the equations of Keller-Segel. \textit{Chemotaxis} is a natural process which induces the organisms to direct their movement according to certain…

Analysis of PDEs · Mathematics 2021-11-24 Alejandro Fernández-Jiménez

It is of great biological interest to understand the molecular origins of chemotactic behavior of E. coli by developing population-level models based on the underlying signaling pathway dynamics. We derive macroscopic models for E.coli…

Analysis of PDEs · Mathematics 2016-05-06 Weiran Sun , Min Tang

We study the Keller-Segel model of chemotaxis and develop a composite particle-grid numerical method with adaptive time stepping which allows us to accurately resolve singular solutions. The numerical findings (in two dimensions) are then…

Analysis of PDEs · Mathematics 2013-02-20 Ibrahim Fatkullin

We show that the Keller-Segel model in one dimension with Neumann boundary conditions and quadratic cellular diffusion has an intricate phase transition diagram depending on the chemosensitivity strength. Explicit computations allow us to…

Analysis of PDEs · Mathematics 2019-04-29 Jose A. Carrillo , Xinfu Chen , Qi Wang , Zhian Wang , Lu Zhang

Kinetic-transport equations are, by now, standard models to describe the dynamics of populations of bacteria moving by run-and-tumble. Experimental observations show that bacteria increase their run duration when encountering an increasing…

Analysis of PDEs · Mathematics 2015-03-16 Benoît Perthame , Min Tang , Nicolas Vauchelet

Directed cell motion in response to an external chemical gradient occurs in many biological phenomena such as wound healing, angiogenesis, and cancer metastasis. Chemotaxis is often characterized by the accuracy, persistence, and speed of…

Cell Behavior · Quantitative Biology 2019-06-19 Julien Varennes , Hye-ran Moon , Soutick Saha , Andrew Mugler , Bumsoo Han

A Keller-Segel model describes macroscopic dynamics of bacterial colonies and biological cells. Bacteria secret chemical which attracts other bacteria so that they move towards chemical gradient creating nonlocal attraction between…

Pattern Formation and Solitons · Physics 2010-05-18 Pavel M. Lushnikov

The interactions between diffusing molecules and membrane-bound receptors drive numerous cellular processes. In this work, we develop a spatial model of molecular interactions with membrane receptors by homogenizing the cell membrane and…

Quantitative Methods · Quantitative Biology 2025-01-24 Anil Cengiz , Sean D Lawley

We consider a simplified chemotaxis model of tumor angiogenesis, described by a Keller-Segel system on the two dimensional infinite cylindrical domain $(x, y) \in \mathbb{R} \times {\mathbf S^{\lambda}}$, where $ \mathbf S^{\lambda}$ is the…

Analysis of PDEs · Mathematics 2019-03-12 Myeongju Chae , Kyudong Choi

Chemotaxis is a directed cell movement in response to external chemical stimuli. In this paper, we propose a simple model for the origin of chemotaxis - namely how a directed movement in response to an external chemical signal may occur…

Analysis of PDEs · Mathematics 2023-06-30 Yishu Gong , Alexander Kiselev

One of simplest examples of navigation found in nature is run-and-tumble chemotaxis. Tumbles reorient cells randomly, and cells can drift toward attractants or away from repellents by biasing the frequency of these events. The post-tumble…

Soft Condensed Matter · Physics 2017-09-14 Julius B. Kirkegaard , Raymond E. Goldstein

We prove uniqueness in the class of integrable and bounded nonnegative solutions in the energy sense to the Keller-Segel (KS) chemotaxis system. Our proof works for the fully parabolic KS model, it includes the classical parabolic-elliptic…

Analysis of PDEs · Mathematics 2012-12-07 J. A. Carrillo , S. Lisini , E. Mainini

We consider the Neumann problem for a coupled chemotaxis-haptotaxis model of cancer invasion with/without kinetic source in a 2D bounded and smooth domain. For a large class of cell kinetic sources including zero source and sub-logistic…

Analysis of PDEs · Mathematics 2020-01-08 Tian Xiang , Jiashan Zheng

We consider the stationary Keller-Segel system from chemotaxis in a ball and we show the existence of a solution concentrating at the boundary of the ball.

Analysis of PDEs · Mathematics 2012-11-09 Angela Pistoia , Giusi Vaira