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Coordination geometries describe how the neighbours of a central particle are arranged around it. Such geometries can be thought to lie in an abstract topological space; a model of this space could provide a mathematical basis for…

Mathematical Physics · Physics 2023-06-28 John Çamkıran , Fabian Parsch , Glenn D. Hibbard

Molecular conformation generation aims to generate three-dimensional coordinates of all the atoms in a molecule and is an important task in bioinformatics and pharmacology. Previous methods usually first predict the interatomic distances,…

Artificial Intelligence · Computer Science 2023-01-02 Jinhua Zhu , Yingce Xia , Chang Liu , Lijun Wu , Shufang Xie , Yusong Wang , Tong Wang , Tao Qin , Wengang Zhou , Houqiang Li , Haiguang Liu , Tie-Yan Liu

Molecular representation learning has attracted much attention recently. A molecule can be viewed as a 2D graph with nodes/atoms connected by edges/bonds, and can also be represented by a 3D conformation with 3-dimensional coordinates of…

Machine Learning · Computer Science 2022-07-20 Jinhua Zhu , Yingce Xia , Lijun Wu , Shufang Xie , Tao Qin , Wengang Zhou , Houqiang Li , Tie-Yan Liu

In the first work of this series [physics/0204035] it was shown that the conformational space of a molecule could be described to a fair degree of accuracy by means of a central hyperplane arrangement. The hyperplanes divide the espace into…

Computational Physics · Physics 2008-12-13 Jacques Gabarro-Arpa

A molecule's 2D representation consists of its atoms, their attributes, and the molecule's covalent bonds. A 3D (geometric) representation of a molecule is called a conformer and consists of its atom types and Cartesian coordinates. Every…

Projective geometry provides the preferred framework for most implementations of Euclidean space in graphics applications. Translations and rotations are both linear transformations in projective geometry, which helps when it comes to…

Computational Geometry · Computer Science 2007-05-23 Chris Doran , Anthony Lasenby , Joan Lasenby

A tutorial of the Mathematica package CGAlgebra, for conformal geometric algebra calculations is presented. Using rule-based programming, the 5-dimensional conformal geometric algebra is implemented and defined functions simplify the…

Mathematical Software · Computer Science 2022-07-01 E. Alejandra Ortiz-Duran , Jose L. Aragon

Estimating 3D geometry from monocular colonoscopy images is challenging due to non-Lambertian surfaces, moving light sources, and large textureless regions. While recent 3D geometric foundation models eliminate the need for multi-stage…

Image and Video Processing · Electrical Eng. & Systems 2025-12-01 Zhiyi Jiang , Yifu Wang , Xuelian Cheng , Zongyuan Ge

Deep learning is changing many areas in molecular physics, and it has shown great potential to deliver new solutions to challenging molecular modeling problems. Along with this trend arises the increasing demand of expressive and versatile…

Machine Learning · Computer Science 2023-12-27 Jun Zhang , Yao-Kun Lei , Yaqiang Zhou , Yi Isaac Yang , Yi Qin Gao

We generalize the background gauge in the Matrix model to propose a new gauge which is useful for discussing the conformal symmetry. In this gauge, the special conformal transformation (SCT) as the isometry of the near-horizon geometry of…

High Energy Physics - Theory · Physics 2016-08-25 Hiroyuki Hata , Sanefumi Moriyama

In a previous work a procedure was decribed for dividing the $3 \times N$-dimensional conformational space of a molecular system into a number of discrete cells, this partition allowed the building of a combinatorial structure from data…

Computational Physics · Physics 2011-05-17 Jacques Gabarro-Arpa

Molecular property prediction, crucial for early drug candidate screening and optimization, has seen advancements with deep learning-based methods. While deep learning-based methods have advanced considerably, they often fall short in fully…

Biomolecules · Quantitative Biology 2024-07-01 Taojie Kuang , Yiming Ren , Zhixiang Ren

In previous works it was shown that protein 3D-conformations could be encoded into discrete sequences called dominance partition sequences (DPS), that generated a linear partition of molecular conformational space into regions of molecular…

Computational Physics · Physics 2009-12-09 Jacques Gabarro-Arpa

Geometric algebra is an optimal frame work for calculating with vectors. The geometric algebra of a space includes elements that represent all the its subspaces (lines, planes, volumes, ...). Conformal geometric algebra expands this…

Computer Vision and Pattern Recognition · Computer Science 2013-06-07 Eckhard Hitzer

Qualifying the discrepancy between 3D geometric models, which could be represented with either point clouds or triangle meshes, is a pivotal issue with board applications. Existing methods mainly focus on directly establishing the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Siyu Ren , Junhui Hou , Xiaodong Chen , Hongkai Xiong , Wenping Wang

We study how to generate molecule conformations (i.e., 3D structures) from a molecular graph. Traditional methods, such as molecular dynamics, sample conformations via computationally expensive simulations. Recently, machine learning…

Machine Learning · Computer Science 2021-04-01 Minkai Xu , Shitong Luo , Yoshua Bengio , Jian Peng , Jian Tang

In this article, we have described the Rao distance (due to C.R. Rao) and ideas of conformal mappings on 3D objects with angle preservations. Three propositions help us to construct distances between the points within the 3D objects in…

Statistics Theory · Mathematics 2021-10-20 Arni S. R. Srinivasa Rao , Steven G. Krantz

The Monte Carlo simulation of the dynamics of complex molecules produces trajectories with a large number of different configurations to sample configuration space. It is expected that these configurations can be classified into a small…

Computational Physics · Physics 2007-05-23 Christoph Best , Hans-Christian Hege

This paper solves the problem of computing conformal structures of general 2-manifolds represented as triangle meshes. We compute conformal structures in the following way: first compute homology bases from simplicial complex structures,…

Graphics · Computer Science 2007-05-23 Xianfeng Gu , Shing-Tung Yau

The identification of the interfacial molecules in fluid-fluid equilibrium is a long-standing problem in the area of simulation. We here propose a new point of view, making use of concepts taken from the field of computational geometry,…

Soft Condensed Matter · Physics 2009-04-30 Florencio Balboa Usabiaga , Daniel Duque
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