English

Visualizing Conformations in Molecular Dynamics

Computational Physics 2007-05-23 v1 Biological Physics Chemical Physics Biomolecules

Abstract

The Monte Carlo simulation of the dynamics of complex molecules produces trajectories with a large number of different configurations to sample configuration space. It is expected that these configurations can be classified into a small number of conformations representing essential changes in the shape of the molecule. We present a method to visualize these conformations by point sets in the plane based on a geometrical distance measure between individual configurations. It turns out that different conformations appear as well-separated point sets. The method is further improved by performing a cluster analysis of the data set. The point-cluster representation is used to control a three-dimensional molecule viewer application to show individual configurations and conformational changes. The extraction of essential coordinates and visualization of molecular shape is discussed.

Keywords

Cite

@article{arxiv.physics/9909049,
  title  = {Visualizing Conformations in Molecular Dynamics},
  author = {Christoph Best and Hans-Christian Hege},
  journal= {arXiv preprint arXiv:physics/9909049},
  year   = {2007}
}

Comments

13 pages, 8 figures, 1 color figure, LaTeX